KEGG   Aeromonas sp. CA23: CK910_12590
Entry
CK910_12590       CDS       T10911                                 
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
  KO
K00166  2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:1.2.4.4]
Organism
aero  Aeromonas sp. CA23
Pathway
aero00280  Valine, leucine and isoleucine degradation
aero00640  Propanoate metabolism
aero00785  Lipoic acid metabolism
aero01100  Metabolic pathways
aero01110  Biosynthesis of secondary metabolites
aero01210  2-Oxocarboxylic acid metabolism
Module
aero_M00036  Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:aero00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00640 Propanoate metabolism
    CK910_12590 (pdhA)
  09105 Amino acid metabolism
   00280 Valine, leucine and isoleucine degradation
    CK910_12590 (pdhA)
  09108 Metabolism of cofactors and vitamins
   00785 Lipoic acid metabolism
    CK910_12590 (pdhA)
Enzymes [BR:aero01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.4  With a disulfide as acceptor
    1.2.4.4  3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
     CK910_12590 (pdhA)
SSDB
Motif
Pfam: E1_dh DXP_synthase_N TPP_enzyme_C HTH_41
Other DBs
NCBI-ProteinID: ATL99229
UniProt: A0AAU8X3N3
LinkDB
Position
2686066..2687160
AA seq 364 aa
MTHVDIPFLRYLDEEGRPVATLPTWLDKAILHTFYRNMVMVRSYDKKAIALQRTGKLGTF
PSHLGAEAVGIGVGLAMQAQDVYVPYYRDMPTLYVRGVPMEKNLQYWGGDERGCVFYKAD
GELSEDLPICVPIATQITHAAGIAAAFKLRNQPRVAVVTIGDGGTSKGDFLEGLNCAGVW
HLPMVMIINNNQWAISVPRKLQSSAPTLAQKGIGAGVRSIQVDGNDVVAVYDATRIAVER
ARTGKGPTLIEAISYRLGDHTTADDATRYRDAAEVEAAWAREPVKRLRQFMAGQGWWDEH
QEQALLAEASREVDRAVAAYEGTAPQAPETLLDYQFAELPKDYRGQRQRIIAKGMQRHAG
EERS
NT seq 1095 nt   +upstreamnt  +downstreamnt
atgacccatgtcgacatccctttccttcgttacctcgatgaggaagggcgcccggtcgcg
acactgccgacctggctggacaaggcgatactgcacactttctaccgcaacatggtgatg
gtgcgcagctatgacaagaaagcaatcgcgctgcagcgaaccggcaaactcggcaccttt
ccctcccatctgggagcagaggcggtcgggataggcgtcggtctcgccatgcaggcgcag
gatgtctatgtgccctactaccgggacatgcccaccctctacgtgcggggcgtgcccatg
gagaaaaacctgcaatattggggcggggatgaacggggctgtgtcttttacaaggccgat
ggcgagctgtcggaggacctgcccatctgcgtgcccatcgccacccagatcacccatgcc
gccggcatagcggcggccttcaagttgcgcaaccagcctcgcgtcgccgtggtcaccata
ggcgacggcggcacctccaagggcgactttctggaggggctcaactgtgccggagtctgg
catctgcccatggtgatgatcatcaacaacaaccagtgggccatctcggtgccgcgcaag
ttgcagtcgagtgcgcccaccctggcccagaaagggataggggccggggtacgcagcatt
caggtcgacggcaacgatgtggtggccgtctatgatgccacccgcatcgccgtggagcgg
gcgcgcaccggcaagggcccgaccctcatagaggcgatcagctatcgactgggggatcac
accacggccgacgatgcgacccgctatcgcgatgccgccgaagtggaagccgcctgggcc
agggagccggtcaagcggctgcgccagttcatggccggacagggctggtgggacgaacat
caggagcaggcgctgctggccgaggcgagccgggaggtcgatcgcgccgtggctgcctat
gaaggcacggccccgcaggcaccggaaaccctgctcgactatcagtttgccgagttgccc
aaggattatcgcggccagcgccagcgcatcatcgccaagggcatgcagcgtcacgccggg
gaggaacgctcatga

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