Aeromonas sp. 1805: E5E96_00580
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Entry
E5E96_00580 CDS
T10912
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
aerz Aeromonas sp. 1805
Pathway
aerz00260
Glycine, serine and threonine metabolism
aerz00261
Monobactam biosynthesis
aerz00270
Cysteine and methionine metabolism
aerz00300
Lysine biosynthesis
aerz01100
Metabolic pathways
aerz01110
Biosynthesis of secondary metabolites
aerz01120
Microbial metabolism in diverse environments
aerz01230
Biosynthesis of amino acids
Module
aerz_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
aerz_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
aerz_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
aerz00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
E5E96_00580 (thrA)
00270 Cysteine and methionine metabolism
E5E96_00580 (thrA)
00300 Lysine biosynthesis
E5E96_00580 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
E5E96_00580 (thrA)
Enzymes [BR:
aerz01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
E5E96_00580 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
E5E96_00580 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
ACT_9
AA_kinase
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QJT15929
LinkDB
All DBs
Position
complement(140385..142844)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADAERFLRVADIAVNTHGQSQVALVLSAPAKVTNHLVALVEQTSRGMDA
SSTLFEINGIFSRLLAGLKAAYPALDDKALQARLTSELDQVERLMQGIRLLGLCPDNVQA
RILSRGENLSIAFMHELLRVRGLELDIIVPEQLLATDGGYLEAHVDIEASRLRFAAKGLR
SDCLYLMPGFTGGSDKGETVLLGRNGSDYSAAVLAACVDAECCEIWTDVEGCYNCDPRLV
PDAYLLKTLSYKEAMELSYFGAKVLHPKTIAPVAQFHIPCLIKNSFNPQGPGTLIGVEQG
DDDLKVKAISDLSGMCMFNVSGPGMKGMVGMAGRIFSAVSRAGVSIVLITQSSSEYSVSF
CIHSYDCDKTRKVLEREFELEFKNQLLDPLEIMQDLAIISLIGDGMRTSKGMAARFFTSL
AQASINIVAIAQGSSERSISAVVRDRKVAEAIKACHQNFFGSQQFIDLFVVGVGGVGAAL
VDQIARQQPVLAEQGTGLRVVGIANSRQMAVNKDGLNLANWREQLVEARDSFSLEAVQKL
VEESHLINPVIVDCTSSEAIAVQYADFLAAGFHVVTPNKKANTGSLDYYKALRRTARQTR
RKFLYETNVGAGLPVIENLQNLIKAGDKLRAFDGVLSGSLSFIFGKLDEGMAFSDATKIA
RGNGFTEPDPRDDLNGMDVARKLLILAREAGMALELSDVEVEQALPPGFDVSGDVEAFMA
RLPEADGWFRDQFAAAQAQGKVLRYVGSIEGGKCKVAIKAVGADEPLFKVKDGENALAFF
STYYQPIPLVLRGYGAGTEVTAAGVFADVLRTQNWKQEL
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgagagtgttgaagtttggcgggtcgtcactggccgatgcagagcgttttttacgggtc
gccgatatcgcggtgaatacccacggccaatcccaggttgccctggtgctgtcggcaccg
gccaaggtgaccaaccacctggtggcgctggtggaacagaccagccgtggcatggatgcc
agcagcaccttgttcgagatcaacggtatcttctcccgcctgctggcaggcttgaaggca
gcttatccggcgctggatgacaaggcgctgcaggctcgtctcaccagcgaactggatcag
gtggagcggctgatgcagggcatccgtctgctggggctctgcccggacaacgtgcaggcc
cgcatcctgagccggggcgagaacctctccatcgcctttatgcacgagctgctgcgggtg
cgcggcctcgagctggacatcatagtgccggagcagctgctggccaccgacggcggctat
ctggaggcgcacgtcgacatcgaagcctcccgcctgcgcttcgccgccaagggcctgcgc
tccgattgcctctacctgatgccgggcttcaccggtggcagcgacaagggcgagaccgtg
ctgctcggccgtaatgggtcggattactccgccgccgtgctggccgcctgtgtcgatgcc
gagtgctgcgagatctggaccgacgtcgagggctgctacaactgcgacccgcgcctggtg
ccagatgcctatctgctgaagaccctctcctacaaggaggcgatggagctctcctacttc
ggtgccaaggtactgcacccgaaaaccatcgcgccggtggcccagttccacatcccctgt
ctcatcaagaacagcttcaacccgcaggggccggggacgcttatcggcgtcgagcagggg
gatgacgacctgaaagtgaaggccatctcggatctctctggcatgtgcatgttcaacgtc
tccggccccggcatgaagggcatggtcggcatggccggccgcatcttctccgccgtctcc
cgcgccggggtcagcatcgtcctcatcacccagtcatcctccgagtacagcgtcagcttc
tgtatccacagctatgactgcgacaagacccgcaaggtgctggagcgcgagttcgagctc
gaattcaagaaccagctgctggatccgctggagatcatgcaggatctggcgatcatctcc
ctgatcggtgacggcatgcgcacttccaaggggatggcggcccgcttcttcacctcgctg
gcacaagcctccatcaatatcgtcgccatcgcccagggttcgagcgagcgctccatctcg
gcggtggtgcgagatcgcaaggtggcggaagccatcaaggcctgccaccagaacttcttc
ggcagccagcagttcatcgacttgttcgtggtcggcgtcggcggtgtcggcgcggccctg
gtggatcagattgcccgccagcagccggtattggccgaacagggcaccggcctgcgggta
gtgggcatcgccaacagccgccagatggcggtcaacaaggatgggctgaacctcgccaac
tggcgtgaacagctggtggaagcccgtgacagcttcagcctggaagcggtgcaaaagctg
gtggaagagagtcacctcatcaacccggtgatcgtcgattgcacctccagcgaggccatc
gccgtccagtacgctgacttcctcgccgccggcttccacgtggtcaccccgaacaagaag
gccaataccgggtcgctggattactacaaggcgctgcgccgcaccgcccgccagactcgt
cgcaagttcctgtacgagaccaacgtgggcgccggtctgccggtcatcgagaacctgcaa
aacctgatcaaggccggcgacaagctgcgcgccttcgacggcgtgctgtccggttcgctc
tcctttatcttcggcaagctggacgaagggatggccttctccgacgccaccaagattgcc
cgtggcaacggcttcaccgagccggatccccgcgatgatctcaacggcatggacgtggcc
cgcaagctgctcattctggcccgcgaggccggcatggcgctggagctctccgatgtggaa
gtggagcaggcattgccaccgggctttgatgtgagcggcgatgtggaagccttcatggcc
cgcctgccggaggctgacggctggttccgcgaccagtttgcggccgcgcaagctcagggc
aaggtgctgcgctacgtgggctccatcgagggtggcaagtgcaaggtcgccatcaaggcg
gtcggtgccgacgagccgctgttcaaggtcaaagacggggagaacgcgctcgccttcttc
tctacctactaccagccgatcccgctggtgctgcgcggctatggcgccggtaccgaagtg
accgccgcgggcgtctttgccgacgtgctgcgcacccagaactggaagcaggagttgtaa
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