Aeromonas sp. ASNIH5: C2U30_22280
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Entry
C2U30_22280 CDS
T05873
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
aes
Aeromonas sp. ASNIH5
Pathway
aes00280
Valine, leucine and isoleucine degradation
aes00640
Propanoate metabolism
aes00785
Lipoic acid metabolism
aes01100
Metabolic pathways
aes01110
Biosynthesis of secondary metabolites
aes01210
2-Oxocarboxylic acid metabolism
Module
aes_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aes00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
C2U30_22280 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
C2U30_22280 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
C2U30_22280 (pdhA)
Enzymes [BR:
aes01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
C2U30_22280 (pdhA)
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Motif
Pfam:
E1_dh
DXP_synthase_N
TPP_enzyme_C
HTH_41
Motif
Other DBs
NCBI-ProteinID:
AUT44126
UniProt:
A0A2I8D9Y5
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Position
4730730..4731818
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AA seq
362 aa
AA seq
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MTHVDIPFLRYLDEEGRPVATLPTWLDKAMLHTFYRNMVMVRSYDKKAIALQRTGKLGTF
PSHLGAEAVGIGVGLAMQSEDVYVPYYRDMPTLYVRGVPMEQNLQYWGGDERGSVFYKAD
GELSEDLPICVPIATQITHAAGIAAAFKLRNQPRVAVVTIGDGGTSKGDFLEGLNCAGVW
HLPMVMIINNNQWAISVPRKLQSSAPTLAQKGIGAGVRSLQVDGNDVVAVYEATRAAVER
ARSGKGPTLIEAVSYRLGDHTTADDATRYRDGAEVEAAWAREPVKRLRQFMFERGWWDEQ
QEQALLAEAGREVERAVAAYEAITPQAPETLLDYQFAELPKAYLAQRQRIIAKGMQQSGE
GL
NT seq
1089 nt
NT seq
+upstream
nt +downstream
nt
atgacccatgtcgacattcccttccttcgttacctcgatgaggaggggcgcccggtcgcg
acactgccgacttggctggacaaggcgatgctgcacaccttctaccgcaacatggtgatg
gtgcgcagttacgacaagaaagcgatagcactgcagcgaaccggcaaactcggcaccttt
ccctcccatctcggggcggaagcggtggggatcggggtcgggctcgccatgcagtcagag
gatgtctatgtgccctactaccgggacatgcccactctctacgtgaggggcgtgcccatg
gagcagaacctgcagtattggggcggggacgagcgtggcagcgtcttctacaaggccgat
ggcgagttgtcggaagacttgcccatctgcgttcccatcgccacccagatcacccatgct
gccggcatcgcggccgccttcaagctgcgcaaccagcccagggtcgccgtggtgaccatc
ggcgatggcggcacctccaagggagatttccttgaggggctcaactgtgccggtgtctgg
catctccccatggtgatgatcatcaacaacaaccagtgggccatctcggtgccgcgcaag
ttgcagtcgagcgcgcccaccctggcccagaagggtatcggggccggggtgcgcagcctc
caggtggacggcaatgacgtggtggctgtctatgaggcgacccgcgctgccgtcgagcgg
gctcgcagcggcaaggggccgacgcttatcgaagccgtcagctaccggctcggggatcac
accaccgccgatgatgcgactcgctatcgtgacggcgccgaggtggaagcggcctgggcc
agggaaccggtcaagcggctgcgccagttcatgtttgaacggggctggtgggatgagcag
caggaacaggcgctgctggcagaggcgggccgggaagtggaacgcgccgttgccgcctat
gaggccatcacgccccaggcgccggagaccctgctcgattaccagtttgccgagctgccg
aaggcctatcttgcccagcgccagcgcatcatcgccaagggcatgcagcagagcggggag
ggactatga
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