Actinopolyspora erythraea: CDG81_06950
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Entry
CDG81_06950 CDS
T05020
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
aey
Actinopolyspora erythraea
Pathway
aey00290
Valine, leucine and isoleucine biosynthesis
aey00660
C5-Branched dibasic acid metabolism
aey01100
Metabolic pathways
aey01110
Biosynthesis of secondary metabolites
aey01210
2-Oxocarboxylic acid metabolism
aey01230
Biosynthesis of amino acids
Module
aey_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
aey00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
CDG81_06950 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
CDG81_06950 (leuC)
Enzymes [BR:
aey01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
CDG81_06950 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
CDG81_06950 (leuC)
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GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ASU78087
UniProt:
A0A099D7A3
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Position
1530695..1532095
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AA seq
466 aa
AA seq
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MGSTLAEKVWNEHLVRRGTGDEPDLLYIDLHLVHEVTSPQAFEGLRLADRPVRRPDLTLA
TEDHNVPTDGAELPIADPVSRTQVETLRKNCADFGVRLHPMGDSEQGIVHVVGPQLGLTQ
PGTTVVCGDSHTSTHGAFGALAFGIGTSEVEHVLATQTLPLRPFRTMAVNIEGTLRPGVT
SKDVILAVIAKIGTGGGQGYVLEYRGSAVESMTMEARMTMCNMSIEAGARAGMIAPDETT
FAYLEGRPHAPRGADWDEAVAYWRSLRTDDDAVYDAEVTIDADELTPFVTWGTNPGQGLP
LGERVPDPETISDEESRAATEKALEYMGLRAGTPLRDISVDTVFLGSCTNGRIEDLRTAA
GILRDRKVADDVRMLVVPGSMRVRQQAEEERLHEVFEAAGAEWRQAGCSMCLGMNPDQLT
PGERSASTSNRNFEGRQGKGGRTHLVSPVVAAATAVRGTLSSPEDL
NT seq
1401 nt
NT seq
+upstream
nt +downstream
nt
atgggtagcacgctcgccgagaaggtatggaacgagcacctggtgcgtcgcggtacgggg
gacgagccggacctgctctacatcgacctccatctcgtgcacgaggtgaccagcccgcag
gccttcgaggggctgcggttggccgaccgtcccgtacgtcggccggatctgacgttggcg
accgaggaccacaacgtgcccaccgacggcgcggagttgcccatcgccgacccggtgtcg
cgcacgcaggtggaaacgctgcgcaagaactgcgccgacttcggggtacggcttcatccc
atgggggattccgagcagggaatcgtccacgtggtcgggccccaactagggctgacccaa
cccgggaccaccgtggtgtgcggcgacagccacacctcgacgcacggggctttcggtgcg
ctcgccttcgggatcggaacctcggaggtcgagcacgtactggccacccagacgctgccg
ctgcggccgttccgcaccatggccgtcaacatcgaggggacactccgccccggagtgacg
agcaaggacgtcattctcgcggtcatcgccaagatcggaaccggtggcggtcagggctac
gtgctggagtaccgcggctcggccgtggagtccatgacgatggaagcccgcatgaccatg
tgcaacatgtccatcgaagccggtgccagggcgggcatgatagccccggacgagaccacc
ttcgcttacctcgagggacgtccgcacgcgcctcgcggggcggactgggacgaggccgtg
gcgtactggaggtcgttgcgcaccgatgacgacgcggtctacgacgccgaggtgacgatc
gacgcggacgagctcacgccgttcgtgacctgggggaccaatcccggccaggggcttccg
ctcggggagcgggtccccgacccggagaccatctccgacgaggagtcccgagcggccacc
gagaaggcactggagtacatgggcctgcgcgccggcaccccgttgcgcgacatctcggtg
gacaccgtgttcctcggctcctgcaccaacggtcggatcgaggacctgcgcaccgcggca
gggatactgcgtgaccgaaaggtcgccgatgacgtccgcatgctggtggtcccggggtcc
atgcgcgttcgccagcaggccgaggaggagaggctgcacgaggtgttcgaggcggcgggg
gccgagtggcgccaggcggggtgctcgatgtgtctgggcatgaacccggaccagctcacg
ccgggggagcgctcggcctcgacctccaaccggaacttcgagggcagacagggcaagggt
gggcgtacgcacctcgtttcccccgtcgtggcggcggcgacggccgtgcgcggcacgctt
tcctcgccggaggacctgtag
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