Aliarcobacter faecis: AFAEC_0621
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Entry
AFAEC_0621 CDS
T06664
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase, bacterial type
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
afc
Aliarcobacter faecis
Pathway
afc00290
Valine, leucine and isoleucine biosynthesis
afc00620
Pyruvate metabolism
afc01100
Metabolic pathways
afc01110
Biosynthesis of secondary metabolites
afc01210
2-Oxocarboxylic acid metabolism
afc01230
Biosynthesis of amino acids
Module
afc_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
afc00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
AFAEC_0621 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AFAEC_0621 (leuA)
Enzymes [BR:
afc01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
AFAEC_0621 (leuA)
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GFIT
Motif
Pfam:
HMGL-like
HCS_D2
LeuA_dimer
IPMS_D2
Motif
Other DBs
NCBI-ProteinID:
QKF72811
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Position
595536..597086
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AA seq
516 aa
AA seq
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MDKNKIIVFDTTLRDGEQSPGCSMNTEEKIRVALQLEKLGVDVIEAGFAAASPGDFDAVT
QIAKIVKNSTICSLSRAVENDIKQAGLAVASASKHRIHTFIATSPIHMKYKLKMSPEEVI
KRAIHAVEYAKTFVDDVEFSCEDAGRSEISFLKEVMDAVISAGAKTINLPDTVGYRLPTE
LGAMIKELSEYAKDRAIISVHNHNDLGLATANTLAAVLNGARQIEVTINGLGERAGNSAL
EEAVMAIKVRKDVFGDLYTNINTPEIYATSRLVATITGVEPQQNKAIVGKNAFAHESGIH
QDGVLKHQETYEIMRPEDVGVIKDSTLILGKHSGRAAFKDKIAQLGFDSVSDEELNSAFE
RFKVLADKKKDITDDDVRMLITDEALNHDKIYELVGLQISDCSSGMPMAAVSIKFEDKII
KDAGLGDGTMDAIFKTIDRLTGYSGELKDYKVISVSEGKNALAKVTTRVSFENSQSFVGH
GLSIDTMLATANAYIGALNSYLSQKNRLTKNCGHQV
NT seq
1551 nt
NT seq
+upstream
nt +downstream
nt
atggataaaaataaaattattgtatttgatactactttaagagatggagaacaaagtcca
ggttgttctatgaatactgaagagaaaataagagttgcattgcagttagaaaaattggga
gttgatgttatagaagctggttttgcagctgcaagtcctggtgattttgatgctgttact
caaatagcaaaaattgtaaaaaattcaactatttgttcattaagtagagctgttgagaat
gatataaaacaagctggattagcagttgcaagtgcttcaaaacatagaattcatacattt
atagcaacatcaccaatccatatgaaatataagttaaaaatgagtccagaagaagttata
aaaagagctatacatgcagttgagtatgcaaaaacttttgtagatgatgtagaatttagc
tgcgaagatgctggaagaagtgaaatatctttcttaaaagaggttatggatgcagttata
agtgcaggtgcaaaaacaataaacttaccagatactgttggatatagattaccaacagaa
ttaggggctatgattaaagagttaagtgaatatgcgaaagatagagctattatttctgta
cataatcacaatgatttaggtttagcaacggccaatactttagccgcagttttaaatgga
gctagacaaatcgaagttacaataaatggtttaggagaaagagctggaaactctgcttta
gaagaggcagttatggctataaaagtgagaaaagatgtatttggagatttatatacaaat
ataaatacaccagaaatttatgcaacttcaagattggttgctacaattacaggtgttgag
ccacaacaaaataaagctattgttgggaaaaatgcttttgcacatgaaagtggaatccat
caagatggtgttttaaaacatcaagaaacatatgaaattatgagacctgaagatgttgga
gttattaaagatagtactttgattttaggaaaacatagtggaagagcggcatttaaagat
aaaattgcacaattaggttttgatagtgttagtgatgaagagttaaatagtgcatttgag
agatttaaagttttagctgataagaaaaaagatataacagatgatgatgtaagaatgtta
attactgatgaagctttgaatcatgataaaatctatgagttagttggtttacaaataagt
gactgttcaagtggaatgccaatggcagcagtaagcataaaatttgaagataaaattatc
aaagatgcaggtttgggagatggtacaatggatgctatttttaaaacgattgatagactt
acaggatatagtggagagttaaaagattataaagtaatttctgttagtgaagggaaaaat
gctttagcaaaagtaacaacaagagttagctttgaaaatagtcaatcttttgtaggacat
ggtttaagtattgatactatgctagcaactgcaaatgcttatattggagctttaaattca
tatctttctcaaaaaaatagacttacaaaaaactgtgggcatcaggtataa
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