Acidithiobacillus ferrooxidans ATCC 53993: Lferr_2225
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Entry
Lferr_2225 CDS
T00758
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
afe
Acidithiobacillus ferrooxidans ATCC 53993
Pathway
afe00290
Valine, leucine and isoleucine biosynthesis
afe00620
Pyruvate metabolism
afe01100
Metabolic pathways
afe01110
Biosynthesis of secondary metabolites
afe01210
2-Oxocarboxylic acid metabolism
afe01230
Biosynthesis of amino acids
Module
afe_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
afe00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Lferr_2225
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Lferr_2225
Enzymes [BR:
afe01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Lferr_2225
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Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ACH84428
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All DBs
Position
complement(2199359..2200900)
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AA seq
513 aa
AA seq
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MRPAKEHLIIFDTTLRDGEQSPGAAMTRDEKLRIAKALERLRVDVIEAGFPAASNGDFVA
VQAIAAAVKDSRICALARARDEDIRRAGEAIAGAAAGRIHTFIATSPVHMQAKLRMSPDE
VLERAVAAVKLAREYCDDVEFSPEDAGRSEEDFLCRVIEAVIDAGARTINIPDTVGYNLP
DRFGQLVANLRRRVPNADRAIFSVHCHNDLGLAVANSLSAVLHGARQVECTINGLGERAG
NAALEEIVMAVRTRADVFSCDTRIDATQIVPTSKLVSTITGFPIQPNKAIVGANAFAHES
GIHQDGVLKHRETYEIMRAEDVGWAANRMTLGKLSGRAAVRARLEALGIHLDKDVLDTVF
TRFKELADRKAEIFDEDLQALVNEDLQEEQAERYRLGYLRVCSEMGTHPEARVEVLVEGV
AKTAAAVGGGPVDAAFKAIEAVVASGVQLLLYSVNAITTGTDAQGEVTVRLQQDGRIVNG
QGADTDIVLASAKAYLSALNRLQQPQGRRHPQI
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgcgtccagctaaagaacatttgatcattttcgacaccaccttgcgcgatggcgagcaa
tcgccgggcgcggccatgacgcgcgacgagaaactgcgcatcgccaaggccctggagcgc
ttgcgcgtggacgtcatcgaggcgggcttccccgccgccagcaacggcgattttgttgca
gtgcaagcgattgctgctgcggtgaaggacagccgtatctgcgctctggcccgggcccgg
gacgaggacatccgccgcgccggggaggccatcgccggggcggcggcggggcgcatccat
accttcatcgccaccagtccggtacacatgcaggctaaattgcgcatgtcccccgacgag
gtcctggaacgggcggtggcggccgtgaagctcgcccgggagtattgcgacgacgtggag
ttttcgccggaggatgccgggcggtcggaggaggattttctctgccgggtcatcgaggcg
gtgatcgacgccggggcgcgcaccatcaatatcccggacacggtgggttacaaccttccg
gaccgctttgggcagctcgtcgccaatttgcgcaggcgcgtgcccaatgctgaccgggcg
atcttttcggtgcattgtcataacgatctgggcttggccgtggccaactccttgtcggcc
gtcctccacggcgcccgccaggtggagtgcaccatcaacggtctgggcgaacgggcgggc
aatgccgccctggaggagatcgtcatggcggtgcgcacccgcgccgatgtcttctcctgc
gacacccgcatcgacgccacccagatcgtgcccaccagcaagctggtgtccaccatcacc
ggtttcccgatccagcccaacaaggccattgtcggggccaacgcctttgcccacgagtcg
ggcatccatcaggacggtgtcctcaagcaccgggaaacctacgagatcatgcgcgccgag
gacgtgggctgggcggccaaccgcatgaccctgggcaagctctcgggccgggcggcggtg
cgggcgcgcctggaggccttgggcatccatctggacaaggatgtcctcgacacggtcttc
acgcgcttcaaggagttggccgaccgcaaggcggaaatcttcgatgaggatctgcaggcc
ctcgtcaacgaggatctgcaggaggagcaggcggaacgctatcgcctgggttacctgcgt
gtctgctcggagatgggcacccatcccgaagcccgggtggaagtcctggtggaaggcgtg
gccaagaccgccgcggccgtgggcggagggccggtagatgccgccttcaaggccatcgaa
gcggtggtggcaagcggtgtgcagttattgctgtattcggtcaatgccatcacgaccggc
accgacgcccaaggggaggtcacggtgcgcttgcagcaggatggccgcatcgtcaatggt
cagggggcggatacggacatcgtcctcgccagcgccaaggcctatctctcggccttgaac
cgcctgcaacagccccaagggcggcggcatccgcagatctag
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