Aspergillus fumigatus: AFUA_1G05720
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Entry
AFUA_1G05720 CDS
T01017
Name
(RefSeq) c-14 sterol reductase
KO
K00222
Delta14-sterol reductase [EC:
1.3.1.70
]
Organism
afm
Aspergillus fumigatus
Pathway
afm00100
Steroid biosynthesis
afm01100
Metabolic pathways
afm01110
Biosynthesis of secondary metabolites
Module
afm_M00102
Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Brite
KEGG Orthology (KO) [BR:
afm00001
]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
AFUA_1G05720
Enzymes [BR:
afm01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.70 Delta14-sterol reductase
AFUA_1G05720
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Gene cluster
GFIT
Motif
Pfam:
ERG4_ERG24
DUF1295
DUF6020
ALIX_LYPXL_bnd
Motif
Other DBs
NCBI-GeneID:
3507579
NCBI-ProteinID:
XP_750321
UniProt:
Q4WJJ9
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Position
1:complement(1646266..1648281)
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AA seq
518 aa
AA seq
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MKLRNTGQMAFRSPFSNLHVRRSSHKPSHPAFVRQNRSMHYYFRDALNIGAFGIIFGLPC
LLYAFTFFCNDISGCPAPSLLHPSTLSIDKLEQEVGWPEDGIKALYDTQVTMWVLSYYLL
SLLMQVFLPGTEVEGTELACGGRLKYKFNAFLSAVLILSGCAVGTYLYGTEFALWTFLWD
NYVQVITANLIICTAIAIFVYLRSFSVPAPGQLNPELRQLAPGGHTGNVLYDFFIGRELN
PRIKLPIPFVGETARTIDIKVWCEMRPGLLGWIILDLSNIAHQYRTYGYITDSIVLTTAF
QAFYVLDALYMEPALLTTMDVIMDGFGFMLSFGDMVWVPFLYNFQTRYLSVYPSELGLSG
ILIVLAVTAAGYVIFRGANNQKNRFRTDPNDPRVKHLKYIETKTGSKLLISGWWGCARHI
NYLGDWIMSWSYCLPTGVAGYAIIESINPASGEMQKQAVQTPESRGWGMIFTYFYMIYFG
VLLLHRERRDEEKCKRKYGADWNRYTSLVRSRIIPGIY
NT seq
1557 nt
NT seq
+upstream
nt +downstream
nt
atgaagctgcgtaatacgggccaaatggcatttcggtcgccattctccaatctccacgtg
cggagaagctcccacaaaccatcccatcccgcttttgtcaggcagaatcgttctatgcat
tattatttcagggatgcgctgaatattggagctttcggaatcatttttggcctaccctgt
ctgctctacgcattcaccttcttctgcaacgatatctcgggttgtcccgcgccgtcgctt
ctgcacccatcgacactgtcaattgataagctggaacaagaggtcggctggccggaggat
ggaatcaaggctctctatgatactcaggttaccatgtgggttctgagctattacttgcta
agtctgctcatgcaggtgttcctccctggcacagaagttgaaggtaccgagctggcgtgt
ggggggagactcaagtacaaatttaatgcattcctgtcggctgtcttgatcctgtcagga
tgtgcggtaggcacgtacttgtacggcacggaattcgcgctatggactttcctctgggac
aactatgtgcaggtgatcactgccaacctgatcatctgtactgccatcgcgatcttcgtt
tacctccgaagcttctcggttcccgctcctggtcaattgaaccccgagctccggcaactg
gcgccaggcgggcacacaggcaacgtcctgtatgacttcttcattggccgggagcttaac
ccccggatcaagctgcccattccgttcgtgggtgagacggcgcggacgattgacattaag
gtgtggtgtgagatgagacctggcttgcttggatggatcattctggatttgtcgaatatc
gcccatcaataccgcacatatggctacatcaccgattcgatcgtcttgaccactgcgttc
caggccttctatgtccttgatgccctttacatggaaccggctcttttgaccaccatggat
gtcatcatggacgggttcggtttcatgctctccttcggcgacatggtttgggttccgttc
ctctacaacttccaaaccagatacctcagtgtctacccctccgagctcggcctaagtggg
atcctcatcgtcttggccgtcacagccgcggggtatgtgattttccgtggtgccaacaac
cagaaaaaccgcttccgcaccgacccaaatgaccctcgcgtgaagcacctcaagtacatc
gagacgaagaccggctccaagctgctcatttccggctggtggggttgcgctcgtcacatc
aactaccttggcgactggatcatgtcttggtcctactgccttccaacgggcgttgcaggg
tatgcgattattgagagtattaacccggcttctggtgagatgcagaagcaggctgtccag
acgccggaatctcgcggctggggaatgattttcacatacttttacatgatctacttcggt
gtcctgcttcttcaccgcgagaggcgtgatgaggaaaagtgcaagcggaagtatggtgcc
gactggaaccgctatacgtctctggtacgcagcagaatcatcccaggcatctactag
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