Aspergillus fumigatus: AFUA_5G04080
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Entry
AFUA_5G04080 CDS
T01017
Name
(RefSeq) oxidosqualene:lanosterol cyclase
KO
K01852
lanosterol synthase [EC:
5.4.99.7
]
Organism
afm
Aspergillus fumigatus
Pathway
afm00100
Steroid biosynthesis
afm01100
Metabolic pathways
afm01110
Biosynthesis of secondary metabolites
Module
afm_M00102
Ergocalciferol biosynthesis, FPP => ergosterol/ergocalciferol
Brite
KEGG Orthology (KO) [BR:
afm00001
]
09100 Metabolism
09103 Lipid metabolism
00100 Steroid biosynthesis
AFUA_5G04080
Enzymes [BR:
afm01000
]
5. Isomerases
5.4 Intramolecular transferases
5.4.99 Transferring other groups
5.4.99.7 lanosterol synthase
AFUA_5G04080
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
SQHop_cyclase_C
SQHop_cyclase_N
Prenyltrans
Pec_lyase
Motif
Other DBs
NCBI-GeneID:
3505512
NCBI-ProteinID:
XP_747936
UniProt:
Q4WES9
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All DBs
Position
5:1084167..1086564
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AA seq
751 aa
AA seq
DB search
MTGGPIASWRTAAQGHLTPDENGDLKTDYSRWRLLDDRGRQTWHYLESDEENEKWPQSVA
DKHFLGLPTVTPLAPAATNRMFAIHELPELPKAKTPLQCAENGLEFFSKLQLPPGNWACE
YGGPMFLLPGLIITYYVTNTPIPPEYATEIKRYLFARQHPEDGGWGLHIEAHSSVFGTCM
NYVALRLIGVSEDDPRMIKARGLLHKFGGAIYGPHWAKFWLSVLGVMEWECVNPVPPELW
LLPDWVPFTPWRWWIHIRQVFLPMSYLWSKKFTHPLDPLTKQLRQELYTQPYDSISFANH
RNSIHAADNYYPKTWLLNLINQLLVSVWNPYFRIPALVKRAEEWTWELIRMEDENTDYAG
LGPVSNPMNMVACYLHDGPDSYSVRRHRERLNDYMWMKNEGMLMNGTNGVQVWDTAFITQ
AIVVAGFADDPKWRPMLTKALEFLEDHQLRENVPDQEKCYRQHRKGAWPFSNKTQGYTVS
DCTAEGLRSTIQLQEMHNYPRLISVERLKDSVDCLLLMQNPSGGFTEYETTRGSEKLEWL
NAAEVFGGIMIGYDYPECTTASVTALSLFSRFYPDYRADEIKAAKDKAVKYIKRVQRPDG
SWYGSWGICFTYAAMFALESLASVGETYETSEYARRGCEFLLSKQKEDGGWGESYLSSEK
HVYVQHEKSQVVQTAWACLALMEAEYPHKEPLQKAMKLLMSRQQPNGEWLQESIEGVFNQ
SCMISYPNYKFYWPIRALGLYSRKFGNEELM
NT seq
2256 nt
NT seq
+upstream
nt +downstream
nt
atgacgggaggcccaattgcgtcgtggagaactgcagctcagggtcacttgactcctgac
gagaacggagacctcaaaacagactattcaagatggagattgttagatgatcggggccgt
cagacctggcattacttggaatccgatgaagaaaacgaaaaatggcctcaatctgtcgct
gacaagcattttctggggctccctacagtaacacctctcgcccctgccgccacgaaccgc
atgtttgccattcacgaacttccagagctgccgaaagcaaaaactccactgcaatgtgcc
gagaatggcctagagtttttctccaaattgcaacttcctccaggcaattgggcctgtgag
tatggaggcccaatgttcttgctcccaggccttattatcacgtactacgtgaccaacact
ccgattccgccggagtatgcgactgagattaaaaggtatctctttgctcgtcagcacccg
gaggacggcggctggggcttgcacattgaggcacatagctctgtctttggaacttgcatg
aactacgtcgcgctgcgcttgatcggtgtcagcgaagacgaccctcgtatgatcaaagcc
cgtgggctcttacataagtttggcggtgccatatatggccctcactgggcgaaattctgg
ctcagtgtcctcggtgtcatggaatgggagtgtgtcaaccccgttccgcctgagctttgg
ctgcttccggattgggttccctttacaccttggcggtggtggatccatatacgtcaagtg
ttcttgcccatgtcgtacctatggtccaagaagttcacccatccgctggatccgctcacg
aaacagttgcgtcaggagctgtacactcagccttacgactctatcagctttgcaaaccac
cggaactcgattcatgcagccgataattactaccccaagacttggcttttgaacctgatc
aaccaacttctcgtctctgtgtggaacccctatttccgaattcctgcgttggtaaaacgc
gcagaggaatggacctgggagttgattagaatggaagacgagaatacggactatgcaggc
ttgggccctgtgagcaacccgatgaacatggtagcttgttatctccatgatgggccagac
agctattcagttcgtcgccatcgtgagcgtctgaatgattacatgtggatgaagaatgaa
ggcatgttgatgaatggaaccaacggggttcaagtgtgggataccgctttcataacgcaa
gcaattgtcgttgccgggttcgcagatgaccccaagtggcgaccaatgctcaccaaagca
ttggagttccttgaagaccatcaacttcgggagaacgtcccagatcaagaaaagtgttac
cgccaacaccgaaaaggcgcgtggccgttcagtaacaagacacaaggctatacagttagt
gattgcacagcggagggcttgcgatccacaatccaactacaggagatgcacaactatcca
aggctgatctccgtggaacgactaaaagacagtgttgactgcttacttctgatgcaaaat
ccctctggcgggttcaccgagtacgaaaccactcgtggctccgagaagctggagtggctc
aatgctgcggaagtgtttggcggaatcatgatcggttatgattatcccgaatgtaccact
gcttctgtcaccgcgctttcgcttttcagcagattttaccctgactaccgggccgacgag
atcaaggctgcgaaagacaaagccgtgaaatatatcaaacgcgtgcagagaccggatggg
agctggtacggatcttggggaatctgcttcacctatgcggccatgtttgccctggaaagc
ctggccagtgtcggggaaacctacgagaccagcgagtatgcgcggcgtggctgcgagttc
ctcctctccaagcaaaaggaggatggaggatggggtgaatcctatctcagcagtgaaaag
catgtgtacgttcaacatgaaaagtcccaagtagtgcaaactgcttgggcttgtcttgca
ctaatggaggcggaatatccacacaaggagccactgcagaaagccatgaagctgctcatg
tcacggcagcaaccaaacggggagtggttgcaagaatccattgagggcgttttcaaccaa
tcttgcatgatatcgtatcccaactacaagttctactggcccattcgagccctgggcctt
tatagccgcaaattcggcaacgaagaactgatgtga
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