Acidimicrobium ferrooxidans: Afer_0598
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Entry
Afer_0598 CDS
T00956
Name
(GenBank) Mur ligase middle domain protein
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
afo
Acidimicrobium ferrooxidans
Pathway
afo00300
Lysine biosynthesis
afo00550
Peptidoglycan biosynthesis
afo01100
Metabolic pathways
afo01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
afo00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
Afer_0598
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
Afer_0598
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
Afer_0598
Enzymes [BR:
afo01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
Afer_0598
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Paralog
Gene cluster
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
ACU53552
UniProt:
C7LXU4
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Position
603468..605048
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AA seq
526 aa
AA seq
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MSSVAGTLGIVIGLASWVGALRWLRVAQREHYIPGRIWLFVRLWLRESPASIVIAVVGFF
GAVSAWSSALPRIPHLIAGAVAAAASIAAPIGLGLRGRTSPLALTWRLRRLALVVVMVDL
VVVGVGIAVGEPLGAAVSAGWLSPLLVDLALRITAPLERRLMGRFVDEATSRLRRVRPRV
VGITGSFGKTTTKGYVAALVEGTYRTLATPASFNNRGGLARAINEHLTSDVEVFVAEMGM
FGPGEIAELVSWVRPEISVITAIGPVHLERLGSEAAIVRAKLEIVETARVVVLNVDYPRL
ALAANALEQEGARRVVRVSAISLEADVAVKPNDEGEVVVYAHGAKIAKAALADVVAGNLA
CAVAVALELGVAPEDIAERLGRIKPAPNRLVAGVSPTSGVEVLDDTYNANPMGARRALDA
LGARRDGGGRRVVVTPGMIELGRRQYLENFKFAKAAAQVASHIIVVGRTNRRALEAGADE
GRDEPGSTLQELRWAPDREHAVALVREMLEPGDVVLYENDLPDHYP
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
gtgagtagcgtcgccggcactctcggaatcgtcatcgggctcgcctcctgggtgggggcg
ctccggtggctccgcgtcgcccaacgcgagcactacatcccgggtcgcatctggctcttc
gtgcgactgtggttgcgtgagtccccggcgtccatcgtcattgcggtggtcgggttcttt
ggggcggtgtctgcgtggagctcggcactgccgcggatccctcacctcatcgcaggagcg
gtcgcggcggccgcgagcatcgcggcgccgatcggcctcggtcttcgcgggcgcacgagc
ccgttggccctcacctggcgcctgcgtcgactggcgctcgtcgtcgtgatggtcgatctc
gtcgtggtcggcgtcggtatcgcggttggcgagccgctcggtgcggccgtgagcgccggc
tggctctcgccgctcctcgtggatctcgcactgcgcatcaccgcgccgctcgagcgcagg
ctgatgggccgcttcgtcgacgaggcgacgtctcggctcaggcgtgttcgcccgcgcgtc
gtcggtatcaccggatcgttcggcaagaccacgacgaagggctacgttgcggccctcgtc
gaggggacgtatcgcacgctcgcgacgcccgcgtcgttcaacaaccgcgggggtctcgct
cgcgccatcaatgagcatctcacatccgacgtcgaggtcttcgttgccgagatgggcatg
ttcggacccggcgagatcgccgagctcgtctcgtgggtcaggccggagatcagtgtcatc
accgccatcggcccggtccacctcgaacggctcggatccgaggcggccatcgtgcgagcg
aagctcgaaatcgtcgagacggctcgggtggtggtgctcaacgtggactatccgcgcttg
gcgctggctgcgaacgcgctggagcaggagggcgcgaggcgggtcgttcgggtgtcggcg
atctcgctcgaggcggacgtcgcggtcaagcccaacgacgagggcgaggtcgtcgtctac
gcgcacggcgcgaagatcgccaaggcggcgctcgccgacgtcgtggccggcaacctcgcc
tgcgcggtcgccgtcgcgctcgagctgggggtggcgccggaggacatcgccgagcggctc
ggacgcatcaagccagcgcccaaccggctcgtcgccggcgtctcgccgacctcgggcgtc
gaggtcctcgacgacacctacaacgcgaacccgatgggtgcgcgccgggcactcgatgcg
ctcggcgcgcgccgtgacggtggagggcggcgcgtggtagtgacgccgggcatgatcgag
ctcgggcgccgtcagtacctggagaacttcaagttcgccaaggccgcggctcaggttgct
tcgcacatcatcgtcgtcggacgcaccaatcgacgagccctcgaggccggtgccgacgag
gggcgggacgaacccggctcgacgctccaggagctacgatgggctcccgatcgggagcat
gcggtcgcgctggtccgcgagatgctggagccgggcgacgtcgtcctgtacgagaacgac
cttcccgaccactacccgtag
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