Aptenodytes forsteri (emperor penguin): 103906613
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Entry
103906613 CDS
T08527
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
afor
Aptenodytes forsteri (emperor penguin)
Pathway
afor00270
Cysteine and methionine metabolism
afor00480
Glutathione metabolism
afor01100
Metabolic pathways
afor01240
Biosynthesis of cofactors
afor04216
Ferroptosis
Module
afor_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
afor00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
103906613 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
103906613 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
103906613 (GCLC)
Enzymes [BR:
afor01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
103906613 (GCLC)
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Ortholog
Paralog
GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
103906613
NCBI-ProteinID:
XP_009286831
LinkDB
All DBs
Position
Unknown
AA seq
664 aa
AA seq
DB search
MSENKTEEHGAKPLTSSSCGSAVSIFNYRLMELENLRGSGLRASQQKALHITAGPARGFQ
SQYPCDAFPCTTSAFTWQVEYMLVKFDHENKKVRLVLCGEEVLQTLQDKGEKVNPNHPTL
WRPEYGSYMIEGTPGQPYGGTMSEFNTVQDNMRKRRQEAASVLKENEAVCTVTSFPRLGC
PGFTLPEYKPTPVEGGASKSLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKN
TPSPFIETFPNDDGEAAKAAKPDYIYMDAMGFGMGNCCLQVTFQACSIFEARYLYDQLAT
ICPIVMALSAASPFYRGYVSDIDCRWGVISASVDDRTREERGLEPLKNNHYRISKSRYDS
IDSYLSECGEKYNDIDLTIDKDIYEHLIQEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDD
ANESDHFENIQSTNWQTMRFKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRV
ILSYKLDFLIPLSKVDENMKMAQKRDAVRQGMFYFRKDICKGGNAVVDGCGSAQNGTGTD
AEEYTLMSIDTIINGKEGVFPGLIPILNSYLENMEVDVDTRCTILNYLKLIKKRASGELM
TVARWMREFIAQHPDYKQDSVITDEMNYSLIWKCNQIAQGQAECPELLGVGFNKKQSGNK
TGSL
NT seq
1995 nt
NT seq
+upstream
nt +downstream
nt
atgtcggaaaacaaaactgaggagcatggtgcaaaacctctgacaagttctagctgtgga
agcgccgtctcaatttttaactacaggttgatggagttagaaaatctcagaggcagcggt
ttgagagcctcccagcaaaaggctctgcatatcaccgccggtccagccaggggttttcaa
agccagtacccttgtgatgcatttccatgtacaacttctgcttttacgtggcaggtggaa
tatatgttagtaaaatttgaccatgagaataagaaagtgcgcttggtgctctgcggtgag
gaagttcttcaaaccctgcaagacaagggggagaaggtaaaccccaaccacccaacactc
tggcgaccagaatatggaagctatatgattgaagggacacctgggcagccgtatggggga
accatgtctgaattcaacactgtgcaagacaacatgaggaaaagacggcaagaggccgct
tctgtgctcaaagaaaatgaggctgtttgcactgtgacgtcatttccaaggttagggtgt
cctgggtttacactgccagaatataagccaacgccagtagaaggaggagcttcaaaatcc
ctcttttttccagatgaagccatcaataaacatcctagatttagtacactgaccagaaac
attcggcaccgaagaggagagaaggttgtgataaatgtaccaatatttaaagataagaac
acgccatcaccatttatcgaaacatttcctaatgatgatggagaagcagcaaaggcagct
aaaccagactatatatacatggatgctatgggttttggaatgggaaactgttgtcttcag
gtaacgttccaggcttgcagcatttttgaagcaaggtatctctatgatcagctagccacg
atctgtcccattgtgatggcgttgagcgctgcatctccattctacagaggctacgtgtct
gatattgactgtcgctggggagtaatctctgcatctgtagatgatcgaacacgagaagag
agggggctagaaccactgaagaacaaccattatagaatcagtaaatccagatatgattcc
atagacagttatctatctgaatgtggtgagaaatacaatgacattgatttgacaatagac
aaagatatctacgagcacctaatacaggaaggtattgaccaccttttggcacagcatatt
gcacacttgttcattcgagacccattgactttgtttgaggagaaaatacatctagatgat
gcaaatgaatccgaccattttgagaatattcagtctacaaactggcagacaatgaggttt
aagccacctcctccaaattcagatattggatggagagtggaattcagacctatggaggtc
cagttaacagactttgaaaactctgcatatgttgtgtttgtggtattgctaaccagagtg
attctgtcatataaactggattttctcattcctttgtccaaggtggatgaaaacatgaag
atggcccagaaaagagatgctgtccggcagggaatgttttacttcagaaaagatatttgc
aaaggtggaaacgctgttgtggatggatgtggctctgcacagaatgggacaggcaccgat
gcagaagagtacaccttaatgagcattgatacaattatcaatgggaaggaaggagtcttt
cctggtttgatcccaattttgaattcctatcttgaaaacatggaagtggatgtggacaca
aggtgcaccatcctaaactacttgaagctaataaaaaagagagcatctggagaattaatg
acggttgctcgatggatgagggaatttatcgcacagcacccagactacaagcaagatagc
gtgataactgatgaaatgaattatagccttatttggaaatgcaaccaaatcgcacaaggc
caggcagagtgtcctgaactactgggggtaggatttaataagaaacaaagtggaaacaaa
actggctctttgtaa
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