Acidithiobacillus ferriphilus: K1Y48_09360
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Entry
K1Y48_09360 CDS
T07843
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
afp
Acidithiobacillus ferriphilus
Pathway
afp00230
Purine metabolism
afp01100
Metabolic pathways
afp01110
Biosynthesis of secondary metabolites
Module
afp_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
afp00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
K1Y48_09360 (purL)
Enzymes [BR:
afp01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
K1Y48_09360 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
UEP58528
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Position
1853396..1857247
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AA seq
1283 aa
AA seq
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MLLLRGPAALSAFRVQHLLRILVAGGVPVQSAVAQYVHLVDLGAPLMSAEMGVLAALLHY
GEPAEGDAEDAEEVCVVPRLGTISPWSSKATDIAGHCGLGAVRRIERGVSYRVHKIGDAA
FSAAELQAMSRLLHDPMTESVLPDWAAAEALFARPEPASLIRIPLHKEGRAALRAANASL
GLALAPAELDYLFDYFSGLGRDPSDAELMMFAQANSEHCRHKVFNAAFRLDGQDQALSLF
AMIRETHRLHPQGTLSAYKDNAAVMAGGALSQPFAVGASGEYAVAEERTAILMKVETHNH
PTAISPFPGAATGSGGEIRDEGATGRGGKPKAGLTGFSVSHLRIPGYIQSWESNPYGKSA
RIRSALDIMREGPLGAAAFNNEFGRPAIAGYFRVFECDQDGLHRGYHKPIMLAGGLGQIR
PLLVEKKPLPEGAKVLVIGGPAMLIGLGGGAASSVTSGAGDEQLDFASVQRGNPEMQRRA
QEVIERCIALGENSPILSIHDVGAGGLSNAIPELLHDGGRGGHLQLRAVPNEEQAMSPMQ
IWSNEAQERYVLAVAAADLPRFTEICARERCPWAVLGEATAEDALILEDSLFHDRPVDMT
LSAMLGCPPRMERDSRHVQPDLRPLDLSGADLRAAAYAVLRHPSVASKEFLITIGDRSVG
GLIHRDQMVGPWQVPVADCGVTAADFWNNHGEAMAIGERAPVAVLNPAASARLAIAEALT
NLFAADIAALGDIKLSANWMAAADHPGEDAALYDAVRAAALELCPALDLAIPVGKDSLSM
RSIWREEGVEKAVVSPLSVIISAFAPVADLRKNWTPQWSAQPDTDLWLVDLGRGRLGASI
LAQALGQMGDSTPDLDAPELLRGLFTALQTLRMRELVLAYHDRSDGGLWATLCEMSFASR
CGADIQLPSGADSWSFLFAEEPGVVIQTPAAQRAQIMQIFADAGLAGRAQVTGQVKSDQW
RLYVEQDGQSVLNEAVADLLRTWAETSKRMQALRDDPLCAQEAFAVVAAEETPLFSRLTF
TPQMPMMQTGARPRVAILREQGVNGQIEMAAAFHRAGFAAVDVHMSDLAAGRHRLGDFQA
MAACGGFSYGDVLGAGAGWAKSILFHDRLRDDFTAFFADTSRLALGVCNGCQMLAELRDI
IPGAAHWPRFARNRSEQFEARLAMVEVVDSPSLLFAGMAGTYAPIVIAHGEGRAHFAGDQ
PVVAPVTMRFVDAQGQPAVQYPANPNGSPQGVTGLCNEDGRVSILMPHPERVVRSLQMSW
RPPGWGEATPWMQIFVNARKALG
NT seq
3852 nt
NT seq
+upstream
nt +downstream
nt
atgctgctgcttcgcggtcctgcggcgctgtccgcttttcgtgtgcaacacttgctacgc
atcctcgttgccgggggggttcccgtccagagcgcagtcgctcaatacgtccatctggtt
gatctcggcgcacccctgatgtcggcagaaatgggggtgctggcggctttgctgcattac
ggggagcctgctgaaggagacgcagaggacgcagaggaagtctgtgtggtgccccgtctc
gggaccatctcaccatggtccagcaaggcgacggatattgccggacactgtggattgggt
gcggtgcggcgtatcgaacgaggcgtttcatatcgcgtgcacaaaattggcgatgcggct
ttcagcgcggcggagttacaggcgatgagccggcttctgcacgatcccatgaccgagtcg
gtgttgccggactgggcggcggcagaggcactttttgcccgtccggaacccgcgtcactg
atccgcattcccctgcacaaagaggggcgagccgctttgcgcgcggccaatgccagcttg
ggtctcgcgctcgctccggcggaactggattatctttttgattatttttccggtttggga
cgcgatcccagtgatgccgagttgatgatgtttgcgcaggccaattccgaacactgtcgg
cacaaggtattcaatgcggccttccggctggatggccaggatcaggccctcagccttttc
gccatgattcgcgaaactcaccgcctgcatccgcagggtaccctttccgcctataaggac
aacgccgcggtcatggcgggcggcgcgctgagccagcctttcgcggtgggcgcgtcggga
gaatatgccgtggcggaagagcgcaccgccatcctgatgaaagtcgaaacccacaaccat
ccgacagccatttcgccctttcccggagccgccacggggagtggcggcgagatccgcgac
gagggcgccaccgggcggggcggcaagcccaaggcgggtttgaccggcttctcggtgtca
catctgcggattcccggctatatccagtcatgggagtcgaacccttacggaaagtcggcg
cgtatccgctcggcgctggacatcatgcgcgaaggccccctgggtgctgcggccttcaac
aacgaattcggccgcccggccatcgccggttatttccgggtcttcgaatgtgatcaggat
gggctgcaccgcggctaccataaacccatcatgctggctggcggtctggggcagattcgc
cccctgctggtggagaagaagcctctaccggaaggcgccaaggtgctggttatcggcggg
ccggccatgctcatcggtctgggtggtggcgccgcttccagtgtgaccagcggggcaggg
gatgagcaactggattttgcctcggtgcagcgcggcaatccggaaatgcagcgccgggcc
caggaagtgatcgagcgttgtattgctctgggagagaattcacctattttgtccatccat
gatgtcggggcgggcgggctctccaacgccattcccgagttgttgcacgatggtggtcgt
ggcggccatctgcaactgcgggcggtgcccaatgaagaacaggccatgtcgcccatgcag
atctggagtaatgaggcgcaggagcgttatgtgctggccgtggcggcagcagacctgccg
cgtttcacggagatctgcgcccgcgagcgctgcccctgggcggtcctgggagaagccacg
gcggaggatgccctgattctggaggattccctgttccatgaccggccggtggatatgacc
ctcagcgccatgctgggctgcccgccgcgcatggagcgggacagtcggcatgtgcaaccc
gatttgcggccgctggacttgtctggcgccgacctgcgcgctgccgcctatgccgtcctg
cgccatccttcggtagccagcaaggaattcctgatcaccatcggtgaccgcagtgtcggc
ggcttgattcatcgcgaccagatggtggggccctggcaggtgccggtggccgattgcggc
gttacggcagcggacttctggaataaccacggcgaggccatggccattggcgagcgcgcc
ccggtggcggtgttgaatcccgcggccagcgcccggctggccattgccgaagcccttacc
aacctttttgccgccgatatagccgcgctgggcgatatcaagctctcggccaactggatg
gcggcggcagatcatcctggagaagacgcggcgctctatgacgcggtacgtgccgcggca
ctggaactctgtccggcgctggacctggccatcccggtgggcaaagattccctgtccatg
cgcagcatctggcgggaggagggcgtggaaaaagccgttgtgtcaccgctgtcggtaatc
atctcggcctttgcgcctgtggcggatttgcggaagaactggacccctcagtggtctgcg
caacctgatacggatctctggctggtggatttggggcgtggccgtctgggtgcttccatt
ctggcccaggctctggggcagatgggcgacagtacgcctgatctggatgccccggagttg
ctccgtggcctgttcaccgcattgcagactttgcgcatgcgggaactggtgctcgcctat
catgaccgctccgatggcggcctctgggcgaccctctgcgaaatgtctttcgccagccgt
tgtggggcggacattcaactgccttcgggggcggatagctggtccttccttttcgccgag
gaaccaggagtggttattcagaccccggccgcccagcgcgcgcaaataatgcagattttt
gccgatgccggcctcgctggacgggctcaggtcacgggtcaggtaaaatccgatcagtgg
cgtttgtacgtggagcaggatggccaatccgtcctgaacgaagctgtcgccgatctgctg
cgcacctgggcggagaccagtaagcggatgcaggccttgcgcgatgatccgctgtgcgct
caagaggcctttgctgtggtggccgcagaggaaacgccattgttctcccgtctgaccttc
accccgcagatgccgatgatgcagaccggggccaggccccgcgtggctatcctccgggag
cagggtgtaaacggccagatcgagatggcggcggctttccatcgtgccggttttgccgcc
gtggacgtgcatatgagcgaccttgcggccggtcgtcaccgcttgggagacttccaggcg
atggccgcttgcggcggcttctcctacggagatgtgctgggcgccggtgcgggctgggcc
aaatcgatccttttccatgatcgtctgcgggatgattttaccgccttctttgccgatacc
tcgcgcctggccctgggcgtttgtaatggctgtcagatgttggcggagctgcgcgacatt
atccccggcgcggcgcactggccgcgcttcgcgcgcaaccgctcggagcagttcgaagcg
cggctggccatggtcgaggtcgtggattctccgtcgctgttgttcgcgggtatggcgggc
acctacgcgcctatcgttatcgcccacggcgaaggccgggcgcacttcgccggggatcag
ccggtggtggcgcccgttaccatgcgctttgtggatgcccagggacagcctgcggtgcag
tatccagccaatcccaacggctccccgcaaggcgttaccggcctctgtaatgaggacggc
agggtctccatcctcatgccgcacccggagcgggtcgtgcgcagtttacagatgagctgg
cggccgccggggtggggtgaggctacaccatggatgcagatttttgtgaacgcacggaag
gcgttggggtaa
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