Alcaligenes faecalis JQ135: AFA_00775
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Entry
AFA_00775 CDS
T05446
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
afq
Alcaligenes faecalis JQ135
Pathway
afq00290
Valine, leucine and isoleucine biosynthesis
afq00660
C5-Branched dibasic acid metabolism
afq01100
Metabolic pathways
afq01110
Biosynthesis of secondary metabolites
afq01210
2-Oxocarboxylic acid metabolism
afq01230
Biosynthesis of amino acids
Module
afq_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
afq00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
AFA_00775 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AFA_00775 (leuC)
Enzymes [BR:
afq01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
AFA_00775 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
AFA_00775 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
ASR88110
UniProt:
A0AB33CN63
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Position
complement(179554..180966)
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AA seq
470 aa
AA seq
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MSTVRTLFQKLWDTHRVAAVDNEHDLIYIDRQLLYEVTSPQAFESLRLAGRSVRRPDTAL
TTVDHNVPTRRRNQRLEDPLAQAQIDQMEINSREFGLRYFGLDDERQGIIHVIGPEQGMT
LPGSSIVAGDSHTSTHGAFAALAFGIGTSEVEHVLATQCLATKRMRSLQIDVQGELPATS
TAKDLILHIIAHMGTDGGRDCAIEFTGPAIRALSMEGRMTLCNMAIEAGARIGLVAVDDK
TLDYVRGRPLAPKGQAWDKAEQYWRTLISDEGCQYDQRLQIDAAQVAPTVTWGTSPDMAA
AIDQLVPDPLAAATGKQADAQRALNYMDLQAGQPLAGLAVDRVFIGSCTNARIEDLRSAA
AMVKGKRVASTVRQALVVPGSGLVRRQAEQEGLDQVFTQAGFEWREPGCSMCLGMNEDRL
NPGERCASTSNRNFEGRQGALGRTHLMSPAMAAAAAIAGHLVDIRHWDAV
NT seq
1413 nt
NT seq
+upstream
nt +downstream
nt
atgagcacggtccgtaccctttttcaaaagctctgggatacacatcgcgttgcggcggta
gacaatgagcatgatctgatctacatagaccgccagttgttgtacgaagtcaccagtccg
caagccttcgagagtttgcgcttggccggacgctcggtgcgtcgccccgacaccgcgctg
acgacggtggaccacaacgtgcccacccgccgccgcaatcagcgtctggaagatccgttg
gcccaagcgcagatcgaccagatggaaatcaatagccgggagtttggcctgcgctacttt
gggctggatgacgagcgccaaggcatcatccacgtgatcggacccgaacagggcatgacc
ttgcccggttccagcattgtggctggcgattcccacaccagcacacatggcgcgtttgcc
gccttggcctttggcattggcacctccgaggtggagcatgttctggccacgcagtgcctg
gccacaaagcgcatgcgcagcctgcaaatagacgtgcaaggcgaactgcctgccaccagc
accgccaaggatctgatcctgcacatcattgcccacatgggcacggacggcgggcgggac
tgtgccattgaatttaccggtccggccatccgggccttgtccatggaagggcgcatgacc
ttgtgcaatatggcgatcgaagcgggtgcccgtattggcttggtcgccgtggacgacaag
accctggactatgtgcgcggccgtcccttggcaccgaaaggacaggcatgggacaaggcg
gaacaatactggcgcacgctgatcagcgatgagggttgccaatacgatcagcgcctgcaa
atcgacgccgcacaagtcgcccccaccgtgacctggggcacgtcccccgatatggcggcg
gccatcgaccagcttgtgcctgatccattagcagccgccacgggtaaacaggctgatgct
caacgcgccttgaactatatggatttgcaggccggccaaccgctggcaggcctcgccgta
gatcgggtgtttattggctcctgtaccaacgctcgcattgaagacctgcgtagcgctgcg
gccatggtcaaaggcaagcgagtagccagcacggtgcggcaagccttggtggtccccggc
tcgggactggtacgccgtcaggccgagcaggaaggcttggaccaggtattcacgcaagcc
ggttttgaatggcgcgagccgggctgctccatgtgcctgggcatgaacgaagaccgtctg
aatccgggcgagcgctgcgcctccacctccaaccgtaacttcgagggcaggcagggcgcc
ttgggacgcacacacctgatgagccccgccatggctgctgccgccgcaattgcaggccat
cttgtcgatatccgccactgggacgccgtatga
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