Acidithiobacillus ferrooxidans ATCC 23270: AFE_0662
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Entry
AFE_0662 CDS
T00810
Symbol
ilvD-2
Name
(GenBank) dihydroxy-acid dehydratase
KO
K01687
dihydroxy-acid dehydratase [EC:
4.2.1.9
]
Organism
afr
Acidithiobacillus ferrooxidans ATCC 23270
Pathway
afr00290
Valine, leucine and isoleucine biosynthesis
afr00770
Pantothenate and CoA biosynthesis
afr01100
Metabolic pathways
afr01110
Biosynthesis of secondary metabolites
afr01210
2-Oxocarboxylic acid metabolism
afr01230
Biosynthesis of amino acids
Module
afr_M00019
Valine/isoleucine biosynthesis, pyruvate => valine / 2-oxobutanoate => isoleucine
afr_M00570
Isoleucine biosynthesis, threonine => 2-oxobutanoate => isoleucine
Brite
KEGG Orthology (KO) [BR:
afr00001
]
09100 Metabolism
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AFE_0662 (ilvD-2)
09108 Metabolism of cofactors and vitamins
00770 Pantothenate and CoA biosynthesis
AFE_0662 (ilvD-2)
Enzymes [BR:
afr01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.9 dihydroxy-acid dehydratase
AFE_0662 (ilvD-2)
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Gene cluster
GFIT
Motif
Pfam:
ILVD_EDD_N
ILV_EDD_C
Motif
Other DBs
NCBI-ProteinID:
ACK80919
UniProt:
B7J5V8
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Position
592517..594358
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AA seq
613 aa
AA seq
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MQPGERLLLGLSHARPYTADTNQTVSVPLLGTRPRCHRGWHPRDASPCRTCHEDLMRSDM
IKKGFERTPHRALLKACGVTDQDMDKPFIGVANSFIDIIPGHVHLQEFGRIVKENIRAAG
GVPFEFNTIGVDDGIIMGHDGMRYSLPSRELIADSIETVVQAHHLDALICIPNCDKIVPG
MIMGALRCDVPTVFVSGGPMEAGHLSDGTAIDLVTAFEAVGQFKRGQITQIRLKEIEDKA
CPTCGSCSGMFTANSMNCLMEVLGIALPGNGTILATAAARRDLVRQAADRVVALAMAGGP
TMRQLVDFDAIDNAFILDMAMGGSTNTVLHTLAIAREAGLDYPLARLNDLAQKVAYLAKI
SPALSTVHIEDIGRAGGIPAILHEVHKRNPDVLHLDKPTVSGQSLREIVSAAAVKDSRII
HLASDPISPTGGLRVVFGNLAPEGGIVKIGAVLPAMRKFSGPAKIFESMETAADGILAGE
VKGGDVVVIRYEGPKGGPGMPEMLTPTANIMGMGLGESVALITDGRFSGATRGACIGHIS
PEAAEGGPIGLLKDGDMISLDLDNGKIHVDLSDEELAERRKHWVPIEKPLKSPWLRRYRK
LVTNAANGAILES
NT seq
1842 nt
NT seq
+upstream
nt +downstream
nt
ttgcagcccggcgagcgtctacttcttggcctgtctcacgctaggccctatactgcggat
actaaccagacggtcagtgtgcctttactcggcacacggccacgctgccatcgtgggtgg
catccacgcgatgcatccccttgccgaacttgccacgaggacctcatgcgctccgatatg
atcaaaaagggttttgaacgcactcctcaccgcgccctgctcaaggcctgcggtgtcacc
gaccaggatatggataagcccttcatcggagtggccaactcgttcatcgacattattccc
ggccatgtgcatttgcaggagttcggacgcatcgtcaaggagaacatccgtgcggcaggg
ggtgtgcccttcgagttcaataccatcggtgtggatgacggcatcatcatggggcacgac
ggtatgcgttactcgctcccgagccgtgagctgattgcggactccatcgagacggtggtg
caggcccatcatctggacgcgctcatctgtatccccaactgcgacaagatcgtgcccggt
atgatcatgggcgcgctgcgctgtgacgtccccacggtgttcgtctccggcggccctatg
gaggccggtcatctgtctgacggaacggcgatcgatctggtgacggcctttgaggcggtc
ggccagttcaagcgcgggcagatcacccaaatccgtctcaaagagatcgaggacaaggcc
tgtccgacttgcggctcctgctccggcatgttcacggccaacagtatgaactgcctgatg
gaggtcctcggtatcgcgctgccgggcaacggtaccatcctggcgacggcggcggcgcgc
cgcgacttggtgcggcaggctgcggatcgtgtggtggccctggccatggcgggcggcccg
accatgcggcaactggtggatttcgatgccatcgataatgcgttcatactggatatggcc
atgggcggttccaccaacacggtgctgcacaccctggccatcgcccgggaggccggtctg
gattatcccctggcgcggctgaacgatctggcgcagaaggtggcctaccttgccaagata
tcgcccgccctgtccacggtgcatatcgaggacatcggccgtgccggtggtatcccggcc
atcctccatgaggtccacaagcgcaaccccgatgtgctgcatctggataagccgacagtg
agtggtcagagcctgcgcgagatcgtatcggcggcggcggtcaaggatagcaggatcatc
catctggccagcgatcccatttcacccaccggcggcctgcgggtggtctttggcaatctc
gcgccggaaggcggtatcgtcaaaatcggtgcggtattgcccgcgatgcgcaagttctcc
gggccagcgaagatttttgagagtatggaaacggcggcagacggtattcttgccggtgag
gtcaagggcggtgatgtggtggtgatccgttacgaaggcccgaagggtggccccggaatg
ccggagatgctgacgcctaccgccaacatcatgggtatgggcctgggcgaaagtgtggca
ttgattaccgacggccgtttcagtggagcaactcgcggggcctgtatcggccacatctcc
ccggaggcggcggagggcggccccatcggtctgttgaaagatggtgacatgatttctctt
gacctcgacaacggcaaaattcatgtcgacctgagtgacgaggaattggccgaacgccgc
aaacattgggtgccgatagaaaagcccctgaagtcaccgtggttgcgccgttatcgtaag
ctggtgactaacgccgccaacggcgcgatcctggagtcctga
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