Acidithiobacillus ferrooxidans ATCC 23270: AFE_2066
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Entry
AFE_2066 CDS
T00810
Symbol
folC
Name
(GenBank) folylpolyglutamate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
afr
Acidithiobacillus ferrooxidans ATCC 23270
Pathway
afr00790
Folate biosynthesis
afr01100
Metabolic pathways
afr01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
afr00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
AFE_2066 (folC)
Enzymes [BR:
afr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
AFE_2066 (folC)
6.3.2.17 tetrahydrofolate synthase
AFE_2066 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
BetR
LpxK
Motif
Other DBs
NCBI-ProteinID:
ACK79908
UniProt:
B7J4S6
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Position
complement(1815764..1817053)
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AA seq
429 aa
AA seq
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MALLADSLSDRVAELAGPPEQIVMGLERMRAALAALKMSARLPMPVMLVGGTNGKGSTVV
YLEAFYRQAGYRVGAYTSPHLWQFTERLRLDGRSAPESLWHQQLTEVAATVRQIPLTYFE
IATLAAVRMMLATRVDVAILEVGLGGRLDAVNAFTPDCSIVTTVDLDHQDWLGSDRAAIG
HEKAGIFRRGVPALYGDTEDPCASVLEAAVRADVPLQRLGRDFHIDPLHGKWSGFGHGKD
APPPLWEGAVQWANLALALAAVSLLQEKLPVSDAAVSAWTRLPQLPGRCQWLQPWGKDGP
DLLVDVAHNPQAARQLAALLAARKGSGRCHAVVGMLADKDIAGTLAPLLHWVDAWHVLEI
TDTPRAASMLQLRDTLRGLGATAVSADASMEQALERSRTTLATGDILLCFGSFHLVKQLP
MAWLLSDPS
NT seq
1290 nt
NT seq
+upstream
nt +downstream
nt
gtggcactgctggcggattctctcagcgaccgggtcgctgaactggccgggccacccgag
caaatcgtcatgggtctggagcgaatgcgggccgctctggcggcgctgaagatgtccgcg
cgtttgcccatgccggtaatgctggtgggtggcaccaatggcaagggctccacggtggtt
tatctggaggccttctatcgccaggcgggctatcgcgtcggcgcttataccagcccgcac
ctctggcagtttaccgaacgcctgcggctggatggccggtctgcacccgagtccctctgg
catcagcaactcacggaagtcgccgccacagtccgacagatcccgctcacctatttcgag
atcgcgaccctcgccgcggtacggatgatgcttgccaccagggtcgacgtggcgattctg
gaggtcggcctggggggacgtctggatgcggtcaacgcctttaccccggattgcagtatc
gtaaccaccgtggatctggaccatcaggactggctgggatccgatcgcgcagccatcggc
catgaaaaggcgggtatattccgtcgtggagtgcccgccctctatggggatacggaagac
ccctgtgcttcggtgctggaggcggcggtacgcgccgacgtgcccctgcagcggttgggt
cgggactttcatattgaccccctgcacgggaaatggtcaggatttgggcacgggaaagat
gcgcccccgcctttgtgggagggggccgtacaatgggccaatctggcgctggcgctggcg
gccgtgtcgttgttgcaggagaaattaccagtgtccgatgcggcggtttccgcatggacg
cggctgccgcaattgccgggccgctgtcaatggcttcagccctggggtaaggatggcccc
gatctgctggtggatgtcgcccacaacccgcaggcagcgcggcaactggcggcgttgctg
gcggcgcgaaagggctccgggcgatgtcacgccgtcgtcggcatgctcgccgacaaggat
atcgccgggacgctcgcgccactgctgcactgggtggatgcctggcatgtactggagatc
accgataccccgcgtgcggcgtcgatgctgcagctccgcgataccctccgggggctgggg
gcaacggcggtatcggcagatgccagcatggagcaggccctggagcggtcaagaacgacc
ctggcgaccggagatattttgctttgcttcggctcctttcatctcgtcaaacagttaccg
atggcgtggctgttgagcgacccgtcatga
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