Acidithiobacillus ferrooxidans ATCC 23270: AFE_2354
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Entry
AFE_2354 CDS
T00810
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
afr
Acidithiobacillus ferrooxidans ATCC 23270
Pathway
afr00230
Purine metabolism
afr01100
Metabolic pathways
afr01110
Biosynthesis of secondary metabolites
Module
afr_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
afr00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
AFE_2354 (purL)
Enzymes [BR:
afr01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
AFE_2354 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Zn_ribbon_PRDM4
Motif
Other DBs
NCBI-ProteinID:
ACK79628
UniProt:
B7J6C0
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All DBs
Position
complement(2098914..2102765)
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AA seq
1283 aa
AA seq
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MLLLRGSAALSAFRVQHLLRILVAEGFPVQSAVAQYVHLMDLGAPLRSAEMGVLTALLRY
GEPAEGDAEDAQEVCVVPRLGTISPWSSKATDIAGHCGLGAVRRIERGVSYRLRKVGGAA
FSVAELQAMSGLLHDPMTESVLPDWAAAEAIFAHPEPAALVRIPLRKEGRAALLSANNRM
GLALAPAELDYLFDYFSGLGRDPSDAELMMFAQANSEHCRHKVFNAAFRLDGQDQALSLF
AMVRETHRLHPQGTLSAYKDNAAVMAGGALSRPFAVSASGAYAVAEERTAILMKVETHNH
PTAISPFPGAATGSGGEIRDEGATGRGGKPKAGLTGFSVSHLRIPGYIQSWESNPYGKPA
RIRSALDIMREGPLGAAAFNNEFGRPAIAGYFRVFECDQDGLHRGYHKPIMLAGGLGQIR
PLLVEKKPLPEGAKVLVIGGPAMLIGLGGGAASSVASGAGDEQLDFASVQRGNPEMQRRA
QEVIERCIALGEDSPILSIHDVGAGGLSNAIPELLHDGGRGGRLQLRAVPNEEQAMSPMQ
IWSNEAQERYVLAVAAADLPRFTEICARERCPCAVLGEATAADALILEDSLLHDRPVDMA
LSALLGCPPRMERDSRHVQPDLRPLDLSGADLRAAAYAVLRHPSVASKEFLITIGDRSVG
GLIHRDQMVGPWQVPVADCGVTAADFWNDHGEAMAIGERAPVAVLNPVASARLAIAEALT
NLFAADVAALGDIKLSANWMAAADHPGEDAALYDAVRAAALELCPALDLAIPVGKDSLSM
RTIWREEGVEKTVVSPLSVIISAFAPVADLRKSWTPQWSAQPDTDLWLVDLGCGRLGASI
LAQTLGQMGDSTPDLDAPELIRGLFSALQALRVQELVLAYHDRSDGGLWATLCEMSFASR
CGADIQLPSRADRWSFLFAEEPGVVIQTPAAQREHIMQIFADAGLAGRAQVIGQVKAEHW
RLQIQQDGQSVLNEAVAELLHVWAETSYRMQALRDDPLCAQESFAMVASPDAPLFSRLSF
CPQMPMIQSGARPRVAILREQGVNGQIEMAAAFHRAGFTAVDVHMSDLAAGRHRLPDFQA
MAACGGFSYGDVLGAGAGWAKSILFHDRLRDDFAAFFADTSRLALGVCNGCQMLAELRDI
IPGAAHWPRFARNRSEQFEARLAMVEVVDSPSLLFAGMAGTYAPIVIAHGEGRAHFAGDQ
PGSGPVTMRFVDAQGQPAVQYPANPNGSPQGVTGLCNEDGRVSILMPHPERVVRSLQLSW
RPPEWGEATPWMQIFVNARKALG
NT seq
3852 nt
NT seq
+upstream
nt +downstream
nt
atgctgctgcttcgcggctctgcggcgctgtccgcctttcgtgtgcaacacttgctgcgc
atcctcgtcgccgagggctttcccgtccagagcgcagtcgctcaatacgtccatctgatg
gatctcggcgcgcccctgaggtcggcagaaatgggggtgctgacggctttgctgcgttac
ggggaacctgctgaaggagatgcagaggacgcccaggaagtttgcgtggtgccccgcctc
gggaccatctcgccatggtccagcaaggcgacggatattgccggacactgtggattgggt
gcggtgcggcgtattgaacgaggggtttcgtatcgcttgcgcaaagtcggcggtgcggcc
ttcagcgtggcggagttacaggcgatgagcgggcttttgcacgatcccatgaccgagtcg
gtgttgccggactgggcggcggcagaggccatttttgcccacccagaacccgcagcgctg
gtccgcattcctctgcgcaaagagggacgtgccgccttgctttcggccaataaccgtatg
gggctcgctctcgctccggcggaactggattatctgtttgattatttttccggcttgggc
cgcgatcccagtgatgccgagctgatgatgtttgcgcaggccaactccgagcattgtcgg
cacaaggtgttcaatgcggccttccggctggatggccaggatcaggccctcagcctcttc
gccatggttcgcgaaacgcaccgtctgcatccgcagggtacgctatctgcctataaggac
aatgccgcggtcatggcgggtggcgcgctcagtcggcctttcgcggtgagcgcgtcggga
gcgtatgccgtagcggaagagcgcaccgccatcctgatgaaagtggaaacccacaaccat
ccgacggccatttcgccttttcccggagcggccacggggagtggcggcgagattcgcgac
gagggcgccaccgggcggggcgggaagcccaaggcgggtttgactggattctcggtatcg
catctgcggattcccggctatatccagtcatgggagtcgaatccttacggaaagccggcg
cgtatccgctccgcgctggacatcatgcgcgaaggccctctgggtgctgcggccttcaac
aacgaattcggccgcccggccattgccggctatttccgggtcttcgaatgtgatcaggac
gggctgcaccgcggctaccacaaacccatcatgctcgccggcggtctggggcagattcgc
cccttgctggtggagaagaagcctctgccggaaggtgccaaggtgctggttatcggcggc
ccggccatgctcatcggtctgggtggtggcgccgcatccagtgtggccagcggggcaggg
gacgagcaactggattttgcctcggtgcagcgcggcaatccggaaatgcagcgccgggcc
caggaagtgatcgagcgctgtattgccctgggagaggattcccccattttatccatccat
gatgtcggggcgggcgggctctccaacgccattcccgagttgttgcacgatggtggtcgt
ggcggccgtctgcaactgcgggcggtacccaatgaagaacaggccatgtcacccatgcag
atctggagtaatgaggcgcaggagcgttatgtgctggccgtggcggcagcagacttgccg
cgtttcacggagatctgcgcccgcgagcgctgcccctgtgcagtcctgggagaagccacg
gcggcggacgccctgattctggaggattccctgctccatgaccggccggtggatatggcc
ctcagcgccctgctgggttgcccgccgcgcatggagcgggacagtcggcatgtgcagccc
gatttgcgaccgctggatctgtccggcgccgacctgcgcgctgccgcctatgccgtcctg
cgccatccctcggtggccagcaaggaattcctcatcaccatcggtgaccgcagcgtcggc
ggcctgattcaccgcgaccagatggtggggccatggcaggtgccggtggccgattgcggc
gttactgccgcggacttctggaatgaccacggcgaggccatggccatcggcgaacgtgcc
ccggtggcggtattgaatcctgtagccagtgcccggttggccattgccgaagccctcacc
aatctttttgccgccgatgtggccgcgctgggagatatcaaactctcggccaactggatg
gcggcggcggatcatccaggagaagacgcggcgctctatgacgcggtacgtgctgcggca
ctggagctctgtccggcgctggaccttgccatcccggtgggcaaagactccctatccatg
cgcactatctggcgagaggagggcgtggaaaagaccgtcgtgtcgcccctgtcggtgatc
atctcggccttcgcgcccgtggcggatttgcggaagagctggacccctcaatggtctgct
caacccgatacggatctctggctggtggacttggggtgcggccggctcggcgcttccatt
ctggcccagactttggggcagatgggcgatagtacgcctgatctggatgctcccgagttg
attcgaggcctgttctccgcattgcaggcgttgcgtgtgcaggaactggtgctggcctac
catgatcgctccgacggtggtctctgggcgaccctctgcgaaatgtctttcgccagccgt
tgtggggcggacattcaactgccttcgagggcggatcgctggtccttcctttttgccgag
gaaccgggagtggtcattcagaccccagccgcccagcgcgagcacataatgcagattttt
gccgatgccggcctcgctggacgggctcaggtcattggtcaggtaaaggccgaacactgg
cgtttacaaatacagcaggacggccaatccgttctgaatgaagctgtagctgaactactg
catgtctgggcggagaccagctaccggatgcaggccctgcgcgatgatccgctttgtgcc
caggagtcctttgctatggtggccagcccagatgcgccgctgttttctcgcctgtccttt
tgcccgcagatgccgatgattcagagcggggccaggccccgcgtggcgatcctccgggag
cagggtgtcaatggtcagatcgagatggcggcggctttccatcgtgccggttttaccgcc
gtggacgtgcatatgagcgaccttgcggccggtcgtcatcgcttaccggatttccaggca
atggccgcttgcggcggcttttcctacggagatgtgctgggcgccggtgcgggctgggcc
aaatcgatccttttccatgatcgtctgcgggacgatttcgccgccttctttgccgatacc
tcgcgcctcgccctgggcgtttgcaatggctgtcagatgttggcagagttgcgcgatatt
atccccggcgcagcgcactggccgcgttttgcacgcaatcgctcggagcagttcgaagcg
cggctggccatggtcgaggtcgtggattcgccgtcgctgttatttgcgggtatggcgggc
acttatgcgcccatcgttattgcccacggcgaagggcgggcgcacttcgccggggatcag
cctggctcaggacctgttaccatgcgctttgtggatgcccagggacagccggcagtgcag
tatccagccaatcccaacggctccccgcaaggcgttaccggtctctgtaatgaggacggt
cgggtgtctatcctcatgcctcatcccgaacgggtggtgcgtagcctgcagctgagctgg
cggccgccggagtggggtgaggctacaccctggatgcagatttttgtcaacgcgcggaag
gcgttgggataa
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