Acidithiobacillus ferrooxidans ATCC 23270: AFE_2596
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Entry
AFE_2596 CDS
T00810
Symbol
leuA-1
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
afr
Acidithiobacillus ferrooxidans ATCC 23270
Pathway
afr00290
Valine, leucine and isoleucine biosynthesis
afr00620
Pyruvate metabolism
afr01100
Metabolic pathways
afr01110
Biosynthesis of secondary metabolites
afr01210
2-Oxocarboxylic acid metabolism
afr01230
Biosynthesis of amino acids
Module
afr_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
afr00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
AFE_2596 (leuA-1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
AFE_2596 (leuA-1)
Enzymes [BR:
afr01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
AFE_2596 (leuA-1)
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
ACK78411
UniProt:
B7J7R3
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All DBs
Position
complement(2304658..2306199)
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AA seq
513 aa
AA seq
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MRPAKEHLIIFDTTLRDGEQSPGAAMTRDEKLRIAKALERLRVDVIEAGFPAASNGDFVA
VQAIAAAVKDSRICALARARDEDIRRAGEAIAGAAAGRIHTFIATSPVHMQAKLRMSPDE
VLERAVAAVKLAREYCDDVEFSPEDAGRSEEDFLCRVIEAVIDAGARTINIPDTVGYNLP
DRFGQLVANLRRRVPNADRAIFSVHCHNDLGLAVANSLSAVLHGARQVECTINGLGERAG
NAALEEIVMAVRTRADVFSCDTRIDATQIVPTSKLVSTITGFPIQPNKAIVGANAFAHES
GIHQDGVLKHRETYEIMRAEDVGWAANRMTLGKLSGRAAVRARLEALGIHLDKDVLDTVF
TRFKELADRKAEIFDEDLQALVNEDLQEEQAERYRLGYLRVCSEMGTHPEARVEVLVEGV
AKTAAAVGGGPVDAAFKAIEAVVASGVQLLLYSVNAITTGTDAQGEVTVRLQQDGRIVNG
QGADTDIVLASAKAYLSALNRLQQPQGRRHPQI
NT seq
1542 nt
NT seq
+upstream
nt +downstream
nt
atgcgtccagctaaagaacatttgatcattttcgacaccaccttgcgcgatggcgagcaa
tcgccgggcgcggccatgacgcgcgacgagaaactgcgcatcgccaaggccctggagcgc
ttgcgcgtggacgtcatcgaggcgggcttccccgccgccagcaacggcgattttgttgca
gtgcaagcgattgctgctgcggtgaaggacagccgtatctgcgctctggcccgggcccgg
gacgaggacatccgccgcgccggggaggccatcgccggggcggcggcggggcgcatccat
accttcatcgccaccagtccggtacacatgcaggctaaattgcgcatgtcccccgacgag
gtcctggaacgggcggtggcggccgtgaagctcgcccgggagtattgcgacgacgtggag
ttttcgccggaggatgccgggcggtcggaggaggattttctctgccgggtcatcgaggcg
gtgatcgacgccggggcgcgcaccatcaatatcccggacacggtgggttacaaccttccg
gaccgctttgggcagctcgtcgccaatttgcgcaggcgcgtgcccaatgctgaccgggcg
atcttttcggtgcattgtcataacgatctgggcttggccgtggccaactccttgtcggcc
gtcctccacggcgcccgccaggtggagtgcaccatcaacggtctgggcgaacgggcgggc
aatgccgccctggaggagatcgtcatggcggtgcgcacccgcgccgatgtcttctcctgc
gacacccgcatcgacgccacccagatcgtgcccaccagcaagctggtgtccaccatcacc
ggtttcccgatccagcccaacaaggccattgtcggggccaacgcctttgcccacgagtcg
ggcatccatcaggacggtgtcctcaagcaccgggaaacctacgagatcatgcgcgccgag
gacgtgggctgggcggccaaccgcatgaccctgggcaagctctcgggccgggcggcggtg
cgggcgcgcctggaggccttgggcatccatctggacaaggatgtcctcgacacggtcttc
acgcgcttcaaggagttggccgaccgcaaggcggaaatcttcgatgaggatctgcaggcc
ctcgtcaacgaggatctgcaggaggagcaggcggaacgctatcgcctgggttacctgcgt
gtctgctcggagatgggcacccatcccgaagcccgggtggaagtcctggtggaaggcgtg
gccaagaccgccgcggccgtgggcggagggccggtagatgccgccttcaaggccatcgaa
gcggtggtggcaagcggtgtgcagttattgctgtattcggtcaatgccatcacgaccggc
accgacgcccaaggggaggtcacggtgcgcttgcagcaggatggccgcatcgtcaatggt
cagggggcggatacggacatcgtcctcgccagcgccaaggcctatctctcggccttgaac
cgcctgcaacagccccaagggcggcggcatccgcagatctag
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