Actinoplanes friuliensis: AFR_00725
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Entry
AFR_00725 CDS
T02892
Name
(GenBank) phosphoribosylformylglycinamidine synthase II
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
afs
Actinoplanes friuliensis
Pathway
afs00230
Purine metabolism
afs01100
Metabolic pathways
afs01110
Biosynthesis of secondary metabolites
Module
afs_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
afs00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
AFR_00725
Enzymes [BR:
afs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
AFR_00725
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Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
FGAR-AT_PurM_N-like
DUF2099
Motif
Other DBs
NCBI-ProteinID:
AGZ38434
UniProt:
U5VNR3
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All DBs
Position
156932..159679
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AA seq
915 aa
AA seq
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MTTQHDTATSGAPAPPGVPNQPPAGAKPSGFAATDVLINQFDGGPDTVERALNTSDELQP
HAELGLKDDEYDRIRQILGRRPTASELAMYSIMWSEHCSYKSSKVHLRQFGEKAPKNTRM
LAGIGENAGVVQISDELAVTFKVESHNHPSFVEPYQGAATGVGGIVRDILAMGARPVAVM
DPLRFGAADHPDTARVLPGVVAGIGGYGNCLGLPNIGGEIVFDPCYQGNPLINALSIGVL
PVERLQKKEAAGVGNVVVLLGARTGRDGIGGVSVLASATFDEGAEQRRPSVQVGDPFMEK
LLIESCLELYDAGLVVGIQDLGGAGLTCALTETAAAAGTGMRVYLERVPLREASMSPTEI
LASESQERMLLIVAPEKLDEVLKVADKWGVWATNIGEVTPSETDGQPGRLLISWNDHIVV
DVPPGSLADDGPVYARPIREPADLILLQADRAETLPRPSTPDELRETVLRMIASPNLCDK
SWVTEQYDRYVLGNTVLAQPEDAGVLRIDERTGLGVALSVDGNGRYARLDPYEGARLALA
EAYRNVAVTGADPVAVTDCLNFGSPEDPAVMWQFAEAVRGLADGCQQLGIPVTGGNVSFY
NQTGAAAIHPTPVVGVLGIFADVAKRTPMGFPPPPTAEGDLLFLLGDTECELSGSEWAWV
THGHLGGRPPKVDLAHEQNLGRLMAQASEREHIVAAHDLSDGGLAQVLVESCLRRNVGAR
ITLPEQDAATTPFVWLFSESAGRALVAVPRGHDKAFVALAAEHNVACVQIGVTAEEPVLE
VHNEFTIGLDELREAFTATMRNLFGSPAEGIIRPAVAAAASEPVASVDEPASDIGASDTG
PSITLEISEPAAPEAIPSEPVSSDAASSDAVSSEAASSDVDEPAEKPEAQETGPAAEVAD
IPAAPAAAEKPENKD
NT seq
2748 nt
NT seq
+upstream
nt +downstream
nt
atgaccacccagcacgacacggcgaccagcggcgctccggcgccaccgggggtcccgaac
cagccgccggcgggcgccaagccgagcggcttcgctgccacggacgtgctgatcaaccag
ttcgacgggggtcccgacaccgtcgagcgggcgctcaacacgagcgacgagctgcagccg
cacgccgagctcggcctcaaggacgacgagtacgaccggatccgccagatcctcggccgc
cgtcccaccgcctccgagctggcgatgtactcgatcatgtggagcgagcactgctcctac
aagtcgagcaaggtgcacctgcgccagttcggtgagaaggccccgaagaacacccgcatg
ctcgccggcatcggtgagaacgcgggtgtcgtgcagatctccgacgagctcgccgtcacc
ttcaaggtcgagtcgcacaaccacccgagcttcgtcgagccctaccagggtgcggcgacg
ggtgtcggcggcatcgtccgcgacatcctcgccatgggcgcccgcccggtcgccgtgatg
gacccgctgcgtttcggcgccgcggaccaccccgacaccgcgcgtgtgctgcccggcgtc
gtcgccggcatcggtggttacggcaactgcctcggcctgcccaacatcggcggcgagatc
gtcttcgacccgtgttaccagggcaaccccctgatcaacgccctgagcatcggcgtgctg
ccggtcgagcgcctccagaagaaagaggcggccggcgtcggcaacgttgttgtcctgctc
ggtgcgcgtacgggccgtgacggcatcggcggcgtctccgtgctcgcctcggcgaccttc
gacgaaggtgccgaacagcgccgcccgtcggtgcaggtcggcgacccgttcatggagaag
ctgctcatcgagagctgcctcgagctgtacgacgccggtctggtcgtcggcatccaggac
ctcggcggtgccggcctgacctgcgccctcaccgagaccgcggccgccgcgggcaccggc
atgcgggtctacctggagcgcgtgccgctccgcgaggcctccatgtcgccgaccgagatc
ctggccagcgagtcccaggagcgcatgctcctgatcgtcgcgcccgagaagctcgacgag
gtcctcaaggtcgccgacaagtggggcgtctgggcgaccaacatcggcgaggtcaccccc
agcgagaccgacggccagcccggccgcctgctgatcagctggaacgaccacatcgtcgtg
gacgtgccgcccggctcgctcgccgacgacggccccgtctacgcccggccgataagggaa
cccgccgacctgatcctgctgcaggccgaccgcgccgagaccctcccgcgtccgtccacg
ccggacgagctccgcgagaccgttctgcgcatgatcgcgtcgccgaacctctgcgacaag
agctgggtcaccgagcagtacgaccgctacgtgctcggcaacaccgtgctcgcccagccc
gaggacgccggcgtgctgcgcatcgacgagcgcaccggcctcggggttgcactctccgtc
gacggcaacggccggtacgcccggctcgacccgtacgagggtgcgcggctggcgctggcc
gaggcgtaccgcaacgtcgctgtcaccggcgccgacccggtcgccgtcaccgactgcctc
aacttcggctcacccgaggacccggcagtcatgtggcagttcgccgaggccgtccgcggt
ctcgccgacggctgccagcagctcggcatcccggtcaccggcggcaacgtcagcttctac
aaccagacgggcgccgccgcgatccacccgacccccgtggtcggtgtgctcggcatcttc
gccgacgtggccaagcgcaccccgatgggcttcccgccgccgccgaccgcggaaggcgac
ctgctcttcctgctcggcgacaccgagtgcgaactgtccggctccgaatgggcctgggtc
acccacggccacctcggcggacgcccgccgaaggtcgacctggcacacgagcagaacctc
ggccgcctgatggcgcaggcctccgagcgcgagcacatcgtcgcagcgcacgacctctcc
gacggcggtctcgcccaggtcctggtcgagtcctgcctccggcgcaacgtcggcgcccgc
atcacgctccccgagcaggacgcggccaccaccccgttcgtctggctgttcagcgagtcg
gccggccgcgccctcgtcgccgtcccacgcggccacgacaaggcgttcgtggcgctcgcc
gccgagcacaacgtcgcctgcgtgcagatcggcgtcaccgccgaggagcccgtgctcgag
gtgcacaacgagttcacgatcggcctggacgagctgcgcgaggccttcacggccacgatg
cgcaacctgttcggcagcccggccgagggcatcatccgcccggccgtcgcggctgctgcg
tctgagcccgtcgcctcggtggacgagcccgcatcggacatcggcgcatcggataccggc
ccgtcgatcacgctggagatcagcgagccggcggcacccgaggcgatcccgtccgagccc
gtttcatccgacgctgcctcctccgacgctgtttcgtccgaggctgcttcgtccgacgtg
gacgagcctgccgagaagcccgaggcgcaggagaccggtccggccgccgaggtggccgac
atcccggccgctccggccgccgcggagaagcccgaaaacaaggactga
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