Actinoplanes friuliensis: AFR_10845
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Entry
AFR_10845 CDS
T02892
Name
(GenBank) UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate/D-alanyl-D-alanyl ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
afs
Actinoplanes friuliensis
Pathway
afs00300
Lysine biosynthesis
afs00550
Peptidoglycan biosynthesis
afs01100
Metabolic pathways
afs01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
afs00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
AFR_10845
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
AFR_10845
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
AFR_10845
Enzymes [BR:
afs01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
AFR_10845
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
AGZ40458
UniProt:
U5VTY1
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Position
2345941..2347323
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AA seq
460 aa
AA seq
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MIPLTLADIAAAVRGTVCDGEPGTIVTAPVRHESARVEAGGLFAAFAGARVDGHTFAAEV
IAAGAAAVLASRPVGVPAVVVDDVRDAYALLAAEVVSRLPNLHRIGVTGSSGKTSAKDLL
GRVLGRLGPTVAPPGNPYVPETVLLATEETRFLIVELGARRVGDIAALMPVVRPTVGVVL
GVGSAHLGTFGGRDAIVAAKGELVEALPETGLAVLNADDAAVTAMAARTGARVVTFGRHR
SARVQAERVVLDGRARARFQLRTPVGTAEVALRLHGEHFVTAALAAAAVALEYTHDVWLI
ADALSTAAAVSPGRMRLTDRADGVTVLDDSYSADPESMAAGLRTLTALAAGRRRTVAVLG
QMTELGDASAAAHREIGRTAARLGVDVVITVGGSDAQTLAAAAGPDAVHVADGEAAAERL
DDVLQPGDVLLVKGSNVAELAAGYSVRSAPPSTGRVSPVR
NT seq
1383 nt
NT seq
+upstream
nt +downstream
nt
atgatccccctgacgctcgcggacatcgccgcggcggtacgaggcacggtctgtgacggc
gagcccggcacgatcgtgaccgcgcccgtccgccacgagtccgcgcgcgtcgaggccggc
ggtctgttcgccgccttcgccggggctcgtgtcgacggccacacgtttgccgccgaggtc
atcgccgccggagccgcggcggtcctcgcctcccgtccggtcggggtgccggccgtggtc
gtcgacgacgtccgcgacgcgtacgcgctgctcgccgccgaggtcgtctcgcgcctgccc
aatctgcaccgcatcggagtgaccggttcgtccggcaagacctcggccaaggacctgctc
ggccgggtcctcgggcggctcggcccgaccgtcgcgccgcccggcaacccctacgtgccg
gagaccgtgctgctcgccacggaggagacccgcttcctgatcgtcgagctgggagcgagg
cgcgtcggtgacatcgccgcgctgatgccggtggtgcggcccacggtcggggttgtcctg
ggcgtcggcagcgcacacctcggcacgttcggcgggcgcgacgcgatcgtggcggccaag
ggtgagctggtcgaggcgctgccggagaccggcctggcggtgctcaacgccgacgacgcc
gcggtgaccgcgatggcggcccgcaccggcgcccgggtcgtcaccttcggacggcaccgc
tcggcgcgcgtccaggccgaacgtgtggtgctcgacggccgggcccgcgcccggttccag
ctgcggacaccggtcggcaccgcggaggtggccctgcgcctgcacggcgagcacttcgtc
accgcggcgctggccgcggcggccgtggccctcgaatacacccacgacgtgtggctgatc
gcggacgcgctgagcacggcggcggcggtctcgccgggacggatgcggctgaccgaccgc
gcggacggtgtcacggtgctcgacgactcgtacagcgccgaccccgaatcgatggcggcc
ggcctgcgcacgctgaccgcgctggctgctgggcggcgccgcacggtggcggtcctcggc
cagatgaccgagctgggcgacgcgtcggctgcggcgcaccgcgagatcggccgcacggcc
gcccgcctcggcgtcgacgtggtgatcacggttggcggcagcgacgcgcagacgctcgcg
gcggccgccgggccggacgctgtgcacgtggccgatggtgaagcagcagccgagcggctc
gatgacgtgctgcagcccggcgacgtgctgctggtcaagggctcgaacgtcgcggaactg
gccgccggctacagcgtccgcagtgccccgccgtcgacgggcagggtcagcccggtcaga
taa
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