Aythya fuligula (tufted duck): 116487647
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Entry
116487647 CDS
T07966
Symbol
GCLC
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
aful
Aythya fuligula (tufted duck)
Pathway
aful00270
Cysteine and methionine metabolism
aful00480
Glutathione metabolism
aful01100
Metabolic pathways
aful01240
Biosynthesis of cofactors
aful04216
Ferroptosis
Module
aful_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
aful00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
116487647 (GCLC)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
116487647 (GCLC)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
116487647 (GCLC)
Enzymes [BR:
aful01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
116487647 (GCLC)
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GFIT
Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
116487647
NCBI-ProteinID:
XP_032040625
UniProt:
A0A6J3CQI4
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Position
3:94231087..94263157
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AA seq
636 aa
AA seq
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MGLLSQGSPLSWEETRRHAEHVRKHGILQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRLLLCGEEVLQTLQDKGEKINPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAVCTVTSFPRLGCPGFTVPEYKPTPVEGGASKSLFFPDEAI
NKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKAAKPDYIYMD
AMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYVSDIDCRWGV
ISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTIDKDIYEHLI
KEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENMKVAQKRDAV
RQGMFYFRKDICKGGNVVVDGCGSAQNGTGTDTEEYILMSIDTIINGKEGVFPGLIPILN
SYLENMEVDVDTRCTILNYLKLIKKRASGELMTVARWMREFIAQHPDYKQDSVITDEMNY
SLIWKCNQIAQGQAECPELLGVGFNKKQSGSKTGSL
NT seq
1911 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgctgagctgggaggagacgcggcggcacgccgag
cacgtgcggaagcacggcatcctgcagttcctgcacatctaccgcgccctgcgcgaccgc
cacaaggacgtcctcaagtggggcgacgaggtggagtatatgctagtaaaatttgaccat
gagaataagaaagtacgcttactgctgtgtggcgaagaagttcttcagacgctgcaagac
aagggggagaagataaaccccaaccacccaacgctctggcgaccagaatatggaagctat
atgattgaagggacacctgggcagccatatggaggaaccatgtctgaattcaacactgta
caagacaacatgaggaaaaggaggcaagaggctgcctctgtgctgaaagaaaatgaggct
gtttgcactgtgacatcttttccaaggttagggtgtcctggatttacggtgccagaatat
aagccaacgccagtagaaggaggagcttcaaaatccctcttctttccagatgaagccatc
aataaacatcctaggtttagtacactgacaagaaatatccggcaccgaagaggagagaag
gttgtcataaatgtaccaatatttaaagataagaacacaccatcaccatttatcgaaaca
tttcccaacgatgatggagaagcagcaaaagcagctaaaccagactatatctatatggat
gctatgggttttggaatgggcaactgctgtcttcaggtgacattccaggcttgcagcatt
tctgaagcgaggtatctctatgatcagctagccacaatctgtcccattgtgatggcattg
agtgctgcatctccgttctacagaggctatgtgtctgatattgattgtcgctggggagta
atctctgcatctgtagatgatcgaacacgagaagagagggggctggagccactgaagaac
aaccattatagaatcagtaaatccagatatgattccatagacagttatctatctgaatgt
ggtgagaaatacaatgacattgatttgacaatagacaaagatatctacgagcacctaata
aaggaaggtattgaccaccttttggcacagcatattgcacacttgttcattcgagaccca
ctgactttgtttgaggagaaaatacatcttgatgatgcaaatgaatctgatcattttgag
aacatacagtctacaaactggcagacaatgagatttaagccacctcctccaaattcggat
ataggatggagagtggaattcaggcctatggaggtccagttaacagacttcgaaaactct
gcatacgttgtgtttgtggtactgctaaccagagtgattctgtcatacaaactggatttt
ctcattcctttgtccaaggtggatgaaaatatgaaggtggcccagaaaagagatgctgtc
cggcagggaatgttttacttcagaaaggatatttgcaaaggtggaaatgtcgtcgtggat
ggatgtggctctgcgcagaatgggacaggcacagacacagaagagtacatcttaatgagc
atcgatacaattatcaatgggaaggagggagtctttcctggtttgatcccaattttgaat
tcttaccttgaaaacatggaagtggacgtggacacaagatgcaccatcctaaactacctg
aagttaataaaaaagagagcatctggagagctgatgacagtcgcccgctggatgagggag
ttcatcgcacagcatccagactacaagcaagacagtgtgataacggatgagatgaattac
agccttatctggaagtgcaaccagatcgcacaaggccaggcggagtgccctgaactattg
ggggtaggatttaacaagaaacaaagcggaagcaaaaccggctccttgtaa
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