Aythya fuligula (tufted duck): 116488270 Help Entry 116488270         CDS       T07966                                  Symbol SYNE1 Name (RefSeq) LOW QUALITY PROTEIN: nesprin-1   KO K19326   nesprin-1 Organism aful  Aythya fuligula (tufted duck) Pathway aful04820   Cytoskeleton in muscle cells Brite KEGG Orthology (KO) [BR:aful00001]  09140 Cellular Processes   09142 Cell motility    04820 Cytoskeleton in muscle cells     116488270 (SYNE1)  09180 Brite Hierarchies   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:aful03036]     116488270 (SYNE1) Chromosome and associated proteins [BR:aful03036]  Eukaryotic type   Centrosome formation proteins    LINC complex     116488270 (SYNE1) SSDB OrthologParalogGFIT Motif Pfam:  Spectrin Spectrin_SYNE1 SYNE1 CH Spectrin_SYNE1_2 SR_desmoplakin_3 Motif Other DBs NCBI-GeneID:  116488270 NCBI-ProteinID:  XP_032041638 UniProt:  A0A6J3CWC9 LinkDB All DBs Position 3:complement(52144900..52402245) Genome browser AA seq 8547 aa AA seqDB search MAHYKGAGSRNVTSLNLLPGSFQYRQDEQESVQKRTFTKWINSHLAKRNPPMLVNDLFED IKDGVMLIALLEVLSGQKLPCEQGRQLKRIHWVANIGTALKFLEGRRSVYRGSPIKLVNI NSTDIADGRPSIVLGLVWTIILYFQIEELTSNLPQLQSLSSSTSSVESVVSSETASPPSK RKVVTKVQGSARKALLKWIQYTAAKQVGIEIKDFGQSWRSGVAFHSIIHAIRPDLVDMDK VKGRSNRENLEEAFMLAETELGIPRLLDPEDVNVDKPDEKSIMTYVAQFLKYYPDLHHTV TDVQENDKEDRLMLRDLKVWAEQFERDLARAQVAETSLQEKYQSFKHFRVQYELKRKPIE LATQSLRKDGKLLLDQAIVKQAWDRVSSRLFDWHIQLDKSLPEPLGTIGAWLYRAEVVLR EEVGIQQAHEETANIIHRKLEQLKDLLKNIEGHKKTFHEIHRARSVNGVPVPPDQLEDMA DRFNFVVSSSELHLLKMEFLELKYRLLSLLVLAESKLKSWIIKYGRRESVELLLQNYISV IENSKFFEQYEVTYQILKRAAEVYAKANGSVEEVENVMKFMNETTAQWRNLSVEVRSVRS MLEEVIANWDRYSSTVAGLQAWLEDAEKMLNQPEPSKKDFFRHLPHWIQQHTAMNDAGNF LIETCDEAISRDLKQQLLLLNGRWRELFMQVKQYARADELDKMQKEYLDGVASLTAFVDE SNRKFSAPVEVSFLDVKMFVQDLENIKQKLPAMEAQYKMVTRTVQLVTKEVSQEEVHEML ATLTRIKEQISKVKEYSCALLYESQHLLSPLEELEKQITNFYESLEKVNEIISIQDPEKQ PTILLKQKAQDLVAYQENCKKALSLIERNSQSILQCVASSETLQHFHQSTFQKKVTQVQI TFQNMIRKAGEWRKNIEANSRLMKKFEESRAELEKVIQIANCCLKEKGNPEELLRKHSEF FNQLDQRVLNAFLKACDELTDILPEQEQHSLQEAVRKLHRQWKDLQTEAPYHLIHLKIEV QKNKLLVTVEECKAELVRQNKVLTREGKERMIEEHMLFFGDKGSYHLCEKRLQRIEELCQ KLPVSDPVRATLESSQRILKELKSQIDSTYAKLTEHSDTWKGYKNRFSELANWISSTERE LKKIKESVSDTAKYEQFKSSVGEIRQHINKQGENHSWLKSRLAVLTSICTDTEAKKTEDE LCKLSSDFKGLLDLLAEIEKTLGTLGDCVQYKEEVKSAIEELINNSKEAQAEAEKILDTE SLLQAQQLLFHHQQRTRRLRAKRQDVQQQIFQAKQLQIEGGLPSTMQEDLLKLEGTLENM QQTMEKREEQLQVTINKWEQFERDKETVVKYLNQASSALERILNFSSLESLSSELDQTKE LSKHAEAMTVQAENLVKNSSEIHLGSKNKQSLQQQAKSIQEQVKKVEVTLEEDLKSMEMV KNKWDLFGNNFEALSIWIAEKEKELEILETTSSPLDKQISQIKVINNEIDGKISGISKLE EEAESFSQFVTCGECAHIKAKLTHIKRYWEELRDHAQRLEGTITGNVSAQQKYEECLKQV QQSVSEFETKLAEPLTLCSSSLETYGALQDCMDLCHTVEKLGNTLASLSACARKVANKEK TAQEVTVLQQNYEKVLENAKEKQILLETLLARWQKQEKELSSFLAWLEGCEAAARPSEQY VSADRVKVAGELQSLQDLRADFEPHASVYASLLQLNESLFPTASKECVKAIKDKFKELDE RWKALPQTVDRRINLLQSLVAEHGQFDELLLSFSDWIKQFLAELQATSEINTADQVLAAS QNKNHLMEIESKKQQFRSLKEHLDKLCSFSCPEDQQTLQGKTEDCFQIFQEASQITSQRQ EALDQLQVFLGLHSASSGVLHQLRQTVEKTGNMDKAKSELLEKELHDVIQSLNKLETVAV SLDGSLTKAQYHLKHGNSEQRTSCRAVVDNLCLELEAVQNLLGTKQSEAEALATLRRSFM EHKEQLLKSIEDTEEKADKEGLREATLQALQQRLRVFNQLDEELSSHQHELQWLMDKAKQ IAQKDITLASEIDKEINHLESLWEDTEKVINEKKEQSCILIDLMKEYQSLRSTVMKVIDS ADSASVIKSIWKDHEDVKRTLLKHEAAKNNLSDKQKDLDTFTNKGKHLLAELKRIHNCDC TVVKTDMNSMVDKWLDVSERIEDNIDQLSVSVSLWDDILKIGKEMDGWCNKCISQLNEDI GNLSNSQRIEVILKDFQSQVKDKEQKLEQLSSKILELKDVTHSQEPPADLQFIELDLRQK LEHAKEMSETAKETLKDFSTQKMQLQNFIDQTTDWLTKVEDTLLSCAHNLDSEALNKVKE TQKDLQLQQGSIDSARENLNRLCRKYHSVELETLGGTVTSLIKKYEAVIQLCSRTQASLQ ESLEKHFLYSMQEFQEWFSDVKAAVKASSDRSGDSKAIEAKLHDLQVVMDSISEGRNKLD AACKEGESLYSCLPKPVVIHIQEQIAKSNENFHEFFKQCLNDKQALEACASHLGSFEDHY KKLSLWLHDMEERISTEALGESKQLIPEKKKEVQKVENFLEELLTSRESFDKLSQMAQAL NEEGHGAGREVRLASQHLTNYQNMVKTVKDKLRTCQLALQEHLTLEEALQSMWSWVKEVQ DKLASSESTVGSKATLEKRLTQIQEILLLKGDGEVKLNMAIGKGEQALRSSNEEGQKVIH TELQTLKDVWNDVINTSVNWQSCLESVISQWDEYLERKNQLEQWLEKLNHKVEQPLEPQI GLKEKFAQLDHFQAIVSEIEDHSGDLQQLIEKAAELHEKTEDVFFGEAAREELKTQFNDI ATVAKDKMKKVEDIVKDHLLYLDAVHEFTDWLHSAKEELHRWSDATGDTSTIQKKLAKIN ELVDSRQIGAGRLIRVETLAPAAKRSTTAGGCHVLTAEMQALQSDWKQWEESAFQSQQSL QDVLSQMALSEQEFAVQVAQLEEAVQRFSGLLATWSQSLTPLDGQHTDTEIVESWNKEKE MLDALVKSEHMIDEIKTQLNDLCRFSRDLSTYSSKVSGLIKEYNSLCLQASKGCQSKEQI LQQRFRTTFRDFQQWLVNAKIATAKCFDVPHNISEASESLQKIQEFLSESENGQHKLNQL ASKGELLCSILPKEKGKVIRDKSATAKEDWKKLISTLHQKESALENLKIQMKDFEATAEP LAEWLSTTEKMVQGSSSRLHDLPSKRREHQKLQSVLEEIRCHEHQLNRLKEKAQQLWEEQ AVSKSFMRRVSQLSSQYLTLSNLTKEKVSRMDRVVAEHQQFSHSIKDLQDWVADAVHMLE SYCHPTADKNVLDSRMLKLEGLLTVKQEKEIQMKMVLTRGESVLQNTSLEGVQVIEQQLN TLKDNWASLLSACIQCKSQLEGALSKWTSYQDDVCQFTSWMDKVEASMNASERQYAELRE KNAALSKAKLLNEEVLSHSSLLETIELKGSGMAEHYVTQLELQDLQERYKLLKDRMREAV TKAEGLLNLHQEYQRHLKTFEIWLEKEQEKLDCLLHLEGDVKKQEATLRDLQELQVHCAE GQALLNAAVHAREEVIPWGMPQIEDRALESVRQDWQVYQHRLSEARSQLNATVSRLRLME KKFQKVNDWLTDLEEKVAVRTSRQSSRATKETQLQQMKKWHEEITIYKDDVEEVGILAQQ ILEESLTTSRMGSQATQLTSRYQTLLLHVLEQIKFLEEEIRSMEESELAFSAYTNWYGAT NKNFRNVITKSDVLDKTAMEKKVQELELLLSDMDIGHSLLKSAREKGERAIKYMEENEVD QLRKEIGDHVEQLEELAGSIRKEHMTSEKCLQLAKEFSDKYKAQTQWLTEYQTMLHAPVE PKSELYEKKAQLSKYKSIQQTVLSHEPSIKSVTEKGEALFDLVNDVTLKSNILDLQSSYQ ELCSATKAYVDTLEARVKEHEDYNSDLQEGEKWLLHMSSRLVSPDLMESNNLEIITQQLA NHKAIMEEIAGFEDRLNNLKSKGDYLINQCTEHLQAKFKQNIQSHLQGTRDSYSAICSTA QRVYQSLEHELQKHVNHQDTLQQCQTWLSTIQSELKPSTWPPFSLADAVKQVKHFRALQE QANTYLDLLCSMCDLSDATVKSTATDIQQTKQMIEQQIMNSQYLAQGWEEIKQMKAELWI YFQDADQQLQNLKRRRAELELNVAQNMVLQVKEFNQKLQSKQSALTSVTEKINKLTQGQE SPEHKEIGQLNNQWLDLCLQAHSLLIQREEDLQRTGNYHDRMNVVEVFLEKLTKEWDNLA RSDAESTNMHLEALQKLALALQERRFALEEFKDQKQKMVEHLNLDDKELVKEQFGHFEHR WTQLEDLVKRKIQVSVSTLEEFSLVHSRFQELMEWAEEQQPSISEALKQSPPPDLAQSLL MDHLTICSELEAKQLVLKMLVKDADRVMTNLGLNERQELQKTLSDAQHHVDCLSDLVGQR RKHLNKALSEKTQFLMAVFQATNQIHQHEKKVTFPEHICLFPEDVNKQIRACKNAQANLK TYQNEVTGLWAQGRELMKEAMEQEKSEVLGKLQELQNVYDTVLQKCNQRLLELEKNIVSR KYFKEDLDKVCHWLKQADIVTFPEVNVMNSNSELYTQLSKYQQILEQSPEYENLLLALQR DGQEILPSLNEVDHSYLDEKLNILPQQFNTVTALAKDKFHKVRETIYARKEYASLIELTT KALTELEDQFINTDKAPAAVLAKEAVSLQQAYRDLLGEVVSLGAAVDELNQKKEAFRSTG QPWQPDEMLKLVTLYHKLKRQIEQKINLLEDTIEACQEHEKMCTQLEAQLEAVKKEQIKV NEEMLPIEEKLKIYHSLVGSLQDSGSLLKRITEHMEALSPQLDPSACETTNHQLQSWQDK LKSLHAAIGDTVMDCENRLVQSIDFQTEICRSLDWLRWIKTELNETLILDLKLQSIQEEI RKVQIHQEEVQSSLRVMNALSNKEKEKYMKAKELIPADLENTLAELTELDGEVQEAIHMR QATLDKLYSRCQRYYQVMQIASDWLEDAQEFLHLAGNGLDVENSEGNLRNHIEFFSTESQ FSNHLKELQGLVSEMEPFIQATVREQLVRNLGALEEKGKGTKQDSKTQQELLQRCASEWQ EYQTARQKVIEVMNEAEKKLSEFSLAKAASSHEAEEKLLTHKTLVSIVNSFHEKITALEE KASQLEKVSNDASKATISRSMTTVWQRWTRLKNVAQEQEKILEDAVQEWKGFNDKIEKAT VAIDQLQDRLPESSIEKASKTELLELLDYHSSFLLEVDYQLSSLGLVKQHTLSMLQDVEI KPPSQEELPVMQEIKAMQDRCHNMQQKVKKGVKLVKQELKEREEVEAEINIVKTWIQETK EYLLNPDVEVDTQLQELQSLLGEVTAHRQAVEKMAEQQQNKYLGLYTILPSELSLHLAEV GLALVTVQDQIQTKEKETQHIKTLNQEFGQKIQGIANELNAILSKLKKKTNDIAQAKLEQ KILGEELDSCNIKLVELDASVQDFAEQNIPLAKQLANRIGKLTALHQQTIRQAEYRAAKL SQAASHLEEYNEMLEFILKWSEKANILVHGSITWNSSSQLRDQFKAYQTMLEESGEIHGD LEAMSERIEYLSSVYSTEAMSQQVLELGRRTEELQQVIKGRLPNLQDAAKDMKKFEVELR ALQAALEQAQATLTSPELGRLSLKDQLSHRQHLLSEMESLKPKVHAVQVCQSALRIPEEV VTSLPICHSALRLQEEASRLQHTAIQQCNIMQEAVVQYEQYEQEMKHLQQMIESAHREIQ DKPVPTSNIHELQVQISRHEELAQKIKGYQEQIASLNSKCKMLTMKAKHATMLLTVTEVE GLSEGMEELDSDLLPAHPSHPSVVMMTAGRCHTLLSPVTEESGEEGTNSEISSPPACRSP SPVANTDASVNQDIAYYQALSAEQLQTEAAKIQPSTSATQEFYEQGLESAASAKLDDLQR SWETLKNVISEKQRTLYEALERQQKYQDTLQSISSKMETTEFKLNESLEPSKSPESQMAE HQALMDEILMLQEEITELQTSLAQELVSESRDAEAADQLALQSTLTVLAERMATIRMKAS GKRQLLEEKLSEQLEEQRQEQALQRYRCEADELDHWLLNTRATLDTALVTAEEPMDMEAQ LVDCQNMLVEIEQKVVALSELSVHNENLLMEGKAHTKDEAEQLAVKLRTLKGSLLELQKV LHDKQINIQGSLQEKEENNLDLVSSQSPSVQEWLAQARTTRSQQQQSTLQQQKELEQELE EQKNLLRSVACRGEEILTQQGAPENLSISEKPETLSEELGLEGEKPSSEEQLKLKWESLN HEFNNKQRLLQKALEQEQLQLYHRPNRLISGLPLYKAEGQDEDKSSVSPVLVELNQAFED VSSEAGQAEKERMHLEQKLYDGVTATSLWLDGVEERVFVTTSHLPEEETEIYLSKQESLA KEIKEITEEMDKNKNLFTQTFPENRDNKDVIEDTLDCLLGRLTLLESVVNQRCHQMKGRL QEIVTFKNDVKILFTSLADNKYLVLQKLTEAAEKPETEQMQVILQAEEGLKELDAGISEL KKRVEKLQIDQPAVQELSKLQDTYDEVMKIIGSRRSDLNQNLALKRQYERALQDLADLVE TGQEKMVGDQKMIVASKEEVQLLLDKHKEYFQGLESHMILTETLFRKMSSFALLKETQSH SELMTQASAVLKLAHKRGVELEYILETWMHLDEDYQELTRQLESVEGNIPTVGLVEETED KLRGRIALFQHLRSNLTEYQPKLDQVLDDGKRLLFSVSCSDLESQLNQLGDHWLSNTSKV NKELHRLETILKHWTRYQSESAELTHWLQSAKERLEFWSQQSLTVPQELETVRDHLNSFL EFSKEVDAKSSQKSSVLSTGNQLLRLKKVDTAALRAGLSQIDSQWTELLTQIPAVQEKLH QLQMDRIPSRHAITEVMSWISLMENVIQQDEENIKNVVGQKAVQDYVQKYKGFKIDLNCK QLTVDFVNQSVLQISSQDVESKRSDKTDFAEQLGAMNRRWQILQGLVMEKIQLLESLQES WTEYENNVQYLKSWFETQDKKLKKQQRIGDQASVQNALKDCQELEESIRTKEKEVENIEQ SGLSLIQNKKEEVSSTVMNTLKEINHAWANLDHMVSQLKILLQSVLDQWSIYKVAYEELN SYLMEARYSLSRFYLLTGSLEAVKVQVHNLQSLQDELEKQENSLQKFGSVTNQLLKQCHP PVTETLTTTLKEVNMRWNNLLQEIAERLRSSKGLLQLWQRYKDCYQQCSSTVRQREDQIN ELLKTATSKDIADDEVTSWIQDCNDLLVDLKTAQDSLIVLQELGEELKSQVEASAAAAIQ SDQLSLNQNLSTLEQILRKQQTVLQAGVLDYQTFAKNLQVLEVWITEAEEILKGQDPSHS SDLSAIQSRMEELKSQMLKFSSMAPDLDRLNELGYRLPLNDKEIKRMQNLNRHWSLISSQ TTERFSKLQSFLLQKQTFLEKCETWMDLLVQTEQKLAAEISGNYQSLLEQQRAHELFQAE MFSRQQILHSIISDGQHLIEQGQVDDRDEFNLKLTLLSNQWQGVIRRAQQRRGIIDSQIH QWQRYREMAEKLRKWLVEMSCQPVSDLGNAPIPLQQVRALLDEVQLKEKVVLRQQGSYIL AVEAGKQLLLSADSGAEAALQTELTEIQEGWKIASTQLEEQKKQLALILKDWEKSEKGIG DSLEKLRSFKKKLSQPLPEHHDELHAEQIRCKELENAVEGWTDDLAHLSLLKESLSAYIS ADDISVLSERIELLHRQWEELCHQVSLRRQQVSERLNEWAVFSEKNKELCEWLTQMESKV SQNGDILIEEMIEKLKKDYQEEIAVARENKIQLQQMGERLAKASHESKASEIEYKLGKIN DRWQHLLDLIAARVKKLKETLVAVQQLDKNMSSLRSWLAHIESELSKPIVYETCDSEEIQ RKLNEQQELQRDIEKHSTGVASVLNLCEVLLHDCDACATETECDSIQQATRNLDRRWRNI CAMSMERRLKIEETWRLWQKFLDDYSRFEDWLKTSERTAAFPSSSGVLYTVAKEELKKFE AFQRQVHESLTQLELINKQYRRLARENRTDSNCSLKQMVHEGNQRWDNLQKRVTSILRRL KHFIGQREEFETARDSILVWLTEMDLQLTNIEHFSECDVQAKIKQLKAFQQEISLNNNKI EQIIVQGEQLIEKCEPMDAAVIEEELDELRRYCQEVFGRVERYHKKLIRLPLTDDEHDLS DREVDLDESADLSDIHWHDKSADSILSPHPSSNLSLPLSQPVRSERSGRDTPASVDSIPL EWDHDYDLSRDLETAGSREMHSEEEDGEQEKDFYLRGAASIADIEIPETLDTYVTLTENA LKNFSGETSVLEAHILQLDKALDTSRFQIQQTENIIRSKTPTGPELDSSYKGYMKLLGEC SGTIDSVKRLGYKLKEEEEKLSGLINLNSTETQTAGVIDRWELIQAQALSKELRMKQNLQ QWQQFNSDLNSIWAWLGETEEELEKLRCLDLSTDIQAIEFRIRKLKVSCRRQLITAKQSF YPSICAAQSSLSLTVKRVRSSKSACHR NT seq 25644 nt NT seq  +upstreamnt  +downstreamnt atggctcattacaaaggtgctggcagcagaaatgttacatcgttaaacctgcttcctggg tcctttcagtaccgtcaggatgagcaagagtcagtgcagaaaaggacttttacaaaatgg atcaattctcatctggctaagcgcaatcctcccatgctggtcaatgatctgtttgaagat atcaaagatggggtaatgctgattgcccttttggaggttctttcaggacagaaactgccg tgtgagcagggacgtcagctgaagagaattcactgggttgcaaacattggcacagctctt aagtttctagaaggaagacggtctgtgtacagaggatctccgattaaacttgtcaatata aactcaactgatattgctgatggtagaccttctattgtgcttggcttggtgtggaccata attttatattttcagattgaagagctgaccagcaacctcccacagctgcaatcattgtct agcagtacttcttctgtggaaagtgttgtcagttcagaaactgcaagtcccccaagcaaa cggaaggtggtaaccaaggtccaaggaagtgccaggaaggctttactgaaatggatacag tacacagcagcaaagcaagttggaattgaaatcaaagactttggacaaagttggaggagt ggtgttgcatttcattccattattcatgctatccgtccagatttagtggacatggacaaa gtaaagggaagatcaaatagggaaaatctggaagaagccttcatgcttgcagaaacagaa ctaggaattccaaggctccttgatccagaagatgttaatgttgacaagccagatgaaaag tctatcatgacatacgtagcccagtttttgaagtactaccctgatcttcatcatacggtg actgatgtgcaggagaatgataaggaagacaggttgatgctgagagacctaaaagtgtgg gcagaacaatttgaaagagatttagcccgagcacaggtggcagaaacaagcttacaggaa aaataccagtcatttaagcatttcagagtgcagtatgagttaaaaaggaaaccgattgaa cttgcaacccagtccttacggaaagatggtaaattactgcttgatcaagctatagtgaag caagcatgggacagagtttcttccaggctatttgattggcacatacagcttgataaatct cttcctgaacctttgggtaccataggtgcttggctctatagagcagaggttgttttgagg gaagaagtaggtattcagcaagctcatgaagaaacagcaaatataattcaccggaagctt gaacaacttaaggatctactgaaaaatatagaaggtcacaaaaagacattccatgagatc cacagggccaggtctgttaatggagtacctgttccacctgaccaattagaagatatggca gacaggtttaattttgttgtctcctcatctgagctccatctgttgaaaatggagtttctg gaactgaagtaccgtctactgtcactcttagtccttgcagaatcaaagttaaaatcatgg attatcaaatatggaaggcgagaatcagtggaactactacttcaaaattatatttctgtt attgaaaatagtaagttcttcgagcaatatgaagttacataccagatcttgaaaagagca gctgaagtgtatgccaaagcaaatggctcagtggaagaagttgagaatgtgatgaaattc atgaatgaaacaacagcacagtggaggaacctctcagtagaagtgagaagtgtaagaagc atgttggaagaagtaattgctaattgggacagatacagcagcactgtggcaggtctgcaa gcctggttggaggatgctgaaaaaatgcttaatcagcctgaaccttctaaaaaggatttt ttccggcacttacctcattggatccaacagcatacagccatgaatgatgctggtaatttt ctgattgaaacatgtgatgaggccatttctagagaccttaaacagcaacttctgctacta aatggaagatggagagagttgtttatgcaagttaaacaatatgctcgagcagatgaacta gacaaaatgcagaaggaatacctggatggtgttgccagtttgacagcctttgttgatgaa agcaatagaaaattctcagcacctgtagaagtttccttcctagatgtcaagatgtttgta caagacttagaaaatattaaacagaaattacctgccatggaagctcagtacaaaatggtc acaagaacagtacaacttgttacaaaagaagtttcccaagaggaagtacatgaaatgctt gcaactttgacaaggatcaaagagcagataagcaaggttaaggaatattcctgtgccctg ctatatgaaagtcagcatctgctgtctccactggaagaactggagaaacaaataacaaat ttctatgaatctcttgaaaaagtcaatgaaataatttctattcaggatcctgaaaaacaa cctacaatacttcttaagcaaaaagctcaagatttggtagcttatcaagaaaactgcaag aaagctttgtccctcattgagagaaatagtcagagtatcctgcagtgcgtggcttctagt gaaacgttgcagcatttccatcagtcaacatttcagaagaaagtcacacaagttcagatt acttttcagaatatgatcaggaaagctggtgagtggagaaaaaatatagaagcaaatagc cgtttgatgaagaaatttgaggagtctagagcagaactggagaaagttatacagattgcc aattgttgcttaaaagaaaaaggaaatcctgaagaacttctcaggaagcatagtgaattc tttaaccagttggatcagagagtcctaaatgccttcctgaaagcttgtgatgaacttact gacatccttcctgaacaagagcaacacagcctgcaggaagctgtaaggaaactccatcgg cagtggaaggatcttcaaacagaagctccatatcatttgattcatttgaagattgaagtg cagaaaaacaagcttctggtcacagtggaggagtgcaaagctgaactagttcgtcagaac aaggtgctaaccagagaaggcaaagaaaggatgattgaggaacacatgctgttcttcggt gacaagggatcttaccatctgtgtgagaagagactacaacggattgaggaactctgccaa aaacttccagtttctgatccagtgagggctacgttggaaagtagccaacgaatcctgaag gagctgaaatcccagatagacagcacatacgcaaaactaacagagcactcagacacctgg aagggctataaaaacagattttctgaattggcaaattggatttcatcaacagaaagagaa ctaaagaagataaaggaaagtgtcagtgatactgccaaatatgagcagtttaaatcatct gtgggggaaatcaggcagcatattaacaagcaaggagaaaatcacagctggctgaaatct agacttgctgttctgacatcaatatgtactgatacggaggccaagaaaacagaggatgag ctgtgtaaactttccagtgacttcaagggactcctggatttgctggctgagattgaaaag acattaggcactcttggagactgtgttcagtacaaagaagaagttaaaagcgcaattgaa gagttaatcaacaactctaaagaagcccaagcagaggctgaaaagatcctggatactgaa agtttgttacaagctcaacaactactgtttcatcatcagcaaaggactaggagactccgt gcaaagagacaagatgtgcaacagcagattttccaagctaaacagttgcagattgaaggt ggactgccaagcacaatgcaggaggatttactaaagctggaaggaacactggagaacatg cagcagactatggagaaacgtgaagagcaattgcaggtcacaataaataaatgggagcag tttgaaagggacaaagaaacagttgtaaaataccttaatcaagcaagctctgcacttgaa cgtatcttaaattttagcagcttagagagcctctcttcagaactggatcagacaaaggaa ctttctaaacatgctgaagccatgactgtacaagctgagaatttggtgaagaattcttct gagatacatcttggttcaaagaacaagcagtcccttcaacagcaggcaaaatctatccaa gaacaagtgaaaaaagtagaagttactcttgaagaagatcttaaaagcatggaaatggtg aaaaacaagtgggatctttttggcaataattttgaagctctgtccatctggatagctgaa aaagaaaaagaactggaaattttggaaacaacatcgtctcctttggacaaacaaatcagc caaatcaaggttattaataacgaaatagatggtaaaatatctggaatctcaaaactagaa gaggaagctgagtcattttcccagtttgttacctgtggagaatgtgcccatattaaagcc aaactgactcatatcaaaaggtattgggaagagctaagagatcatgcacagagattggaa ggaacaatcacagggaatgtatcagcacagcagaaatatgaagaatgtctgaaacaggtg caacagtcagtgtctgaatttgaaactaagttagctgagcctctcacattatgcagttca tcactggaaacgtatggagccctgcaggattgcatggacctttgtcatactgtggaaaaa 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aagctcagaggtcggattgcactttttcagcatctgagatctaatctgactgaataccaa cctaaattagaccaggtgctagatgatgggaaaaggctccttttttctgttagttgctca gatctcgaaagccagctgaaccaactaggagaccactggctaagtaacaccagcaaggtt aacaaggagcttcacaggctggagacaatactgaagcactggaccaggtatcagagtgaa tctgctgaactgacacattggttacaatctgcaaaggagcgacttgagttctggagccaa cagtctctgacagttcctcaggaacttgaaactgtccgagaccacctgaattcctttcta gagttttcaaaagaagtggatgctaaatcatcacagaaatcttctgtcctcagtactggg aaccagctcctcagactgaaaaaggtggatacagcagcattgcgtgcaggattatcccag attgacagtcagtggacagagttgctcacacaaatcccagcggtacaagagaaattgcac caactacagatggacagaattccttctcgccatgccatcactgaagttatgagctggatt tccctgatggaaaatgttattcagcaagatgaagagaatataaagaatgtagtaggacag aaggccgttcaggattatgtccaaaagtacaagggtttcaagatagatttaaattgcaaa cagttgacggtagattttgtgaaccaatctgtgctacagattagcagccaggatgttgaa agtaaacgtagcgacaaaactgattttgcagaacaactcggagcaatgaatagacgttgg cagatcctgcaaggcctggtaatggaaaagatccagctgttggaaagtctgcaggaatct tggacggaatatgaaaataatgtgcagtacctaaaatcttggtttgaaacccaagacaag aagctgaaaaagcaacagagaattggagaccaggcttcagtacagaacgctttgaaagat tgtcaggaattagaagaatcaataagaacaaaagaaaaagaagtagaaaacatagaacaa agtggtctgtctttgatacagaacaagaaggaagaagtctcttctactgttatgaataca ctgaaagaaatcaaccatgcctgggccaacttggatcacatggttagccaactaaagata ttgttgcaatctgttcttgatcagtggagcatttacaaagtggcttatgaagaactgaac agttacctgatggaagccagatattctctgtcccgtttctatctccttactggttctttg gaagctgtgaaagtccaagttcataaccttcagagcctacaggatgaactagaaaagcaa gaaaatagtttacagaaatttggttcagtgaccaatcaattgttaaaacaatgtcaccca ccagtgactgaaacacttaccaccactttgaaggaagtgaatatgaggtggaacaacctt cttcaggagattgcagagcggctgcgttccagtaagggtctccttcagctgtggcagaga tacaaggactgttaccaacaatgctcttcaacagtccgtcaacgagaagatcaaatcaat gaactgttgaagactgcaaccagtaaagatattgctgatgatgaagtaacttcttggatt caggactgtaatgatctactcgttgatttaaagacagcacaggattcactgattgttctt caagaactgggagaggagctaaaaagccaggtggaggcttcagcagcagcagctatacag tctgatcaactgtctctgaaccagaatctgtcaaccctagaacaaattctccgcaagcag caaacagtacttcaggctggagtcctggactatcaaacctttgccaagaacctgcaagtc cttgaggtctggataacagaagcagaagaaatactgaaaggacaggatcctagtcactca tctgatctctcagcaatacagagtaggatggaggaactaaaaagtcagatgttgaagttc agcagcatggccccagatttggaccgtcttaatgagctgggttacaggcttcctctgaat gataaagaaatcaaaaggatgcagaacctgaacagacactggtctctcatctcatctcag actacagaaagattcagtaagctgcagtctttcctgctgcagaagcagacctttttggag aagtgtgaaacttggatggatttgttagttcagactgagcagaagctggcagcagagatt tcaggaaactaccagagccttttagagcaacagagggcacatgagctatttcaggcagag atgttcagtcgccagcagattttgcattcaatcatctctgatgggcagcacctcatagag caaggacaagtggatgacagggatgagtttaatctgaagttgacacttctaagtaatcaa tggcaaggagtaattcgtcgggcacagcagaggagggggatcattgacagccagatccac cagtggcagcgctacagggagatggcagagaaactgcgcaagtggctggtggaaatgtcc tgtcagccagtgagtgatctgggaaatgctcctatcccattgcagcaagtcagagcatta ctggatgaagtgcagcttaaagagaaagttgttctaaggcagcaagggagttatatcctt gctgtggaagctgggaagcaattgctgctctctgctgacagtggagctgaggcagccctg cagacagagcttacagaaattcaggagggctggaagatagctagcacccaactggaagaa cagaagaaacagcttgctttaatactgaaagactgggaaaaatctgaaaagggcatagga gactccctggagaagctaagatcattcaaaaaaaagctttctcagcctttgccagaacac catgatgagttgcacgcagagcagattcgttgcaaggagttagagaatgctgttgaagga tggacagatgaccttgcacacctctctctgctgaaggagtccctgtctgcatatatcagt gcagatgatatttcagtcctcagtgagcgaatagagcttctgcacagacagtgggaggag ctgtgccatcaggtctccttacgtcgacagcaagttagtgagagactgaatgagtgggct gtcttcagcgagaagaacaaggagctctgtgagtggctgacacaaatggaaagtaaagtt tctcaaaatggtgacatcctcatagaagaaatgattgagaaacttaaaaaggattatcaa gaggaaattgctgtagctcgggagaacaaaatccagctccagcaaatgggagagcgactt gctaaagccagccatgagagtaaagcatcagagattgagtacaaacttggcaagatcaat gacagatggcaacatcttctggaccttattgcagccagggtaaagaagttgaaagaaacc ctggttgcagtgcagcagctggataagaacatgagtagcctgagatcttggcttgcccat attgagtcagagctgtccaaaccaattgtctatgaaacttgcgactctgaggagatacaa aggaagctaaatgaacagcaggaacttcagagggacatagagaaacacagcactggagta gcatctgttctcaatttgtgtgaagtgcttcttcatgactgtgatgcctgtgccacagaa acagagtgtgactctatccagcaggctacacgtaacctggacagaaggtggaggaacatt tgtgcaatgtcaatggaaaggcgacttaaaattgaagagacatggcggttatggcaaaag tttttggatgactactcaagatttgaagattggctaaaaacctctgagaggacagctgct ttcccaagctcctctggtgtactttacacggttgctaaggaagaactgaagaaatttgag gccttccagagacaggtgcatgaaagtctgactcagctggaactgattaacaagcaatat cgtcgcctggctcgggaaaaccgtactgattctaactgcagcctcaagcagatggtccat gaggggaaccagagatgggacaacttacaaaagcgagttacttccatcctgcgcaggcta aaacattttattggccagcgtgaggagtttgagacagcacgtgatagcatcctggtttgg ctaacagagatggatctgcaactgaccaacatagagcatttctcagagtgtgatgtccaa gcaaagataaagcaacttaaggctttccagcaagaaatttccctgaacaacaacaaaatt gagcagataattgtgcagggagagcaactcattgagaaatgtgagccaatggatgcagct gtcattgaagaagaattagatgagctgcgtcgttactgtcaagaggtctttggacgtgtg gaacgttatcacaagaaactgatccgtcttcctctgacagatgatgaacatgacctctct gacagagaggtggatctggatgaatcagcagatctctctgatatacactggcacgacaaa tctgcagacagcattctctccccccatccttcttccaacctttcactgcccctttcacag ccagtgagaagtgagcgatcaggtcgggacacccctgcaagtgtagactccatcccactg gagtgggatcatgattatgaccttagcagagacctggagacggctggttcacgggaaatg cactctgaggaagaagatggagaacaagagaaagacttctacctgagaggagcagcaagt atagcagatatagagatccctgaaactcttgacacctatgtcacacttacagaaaacgca ctcaaaaatttctctggagaaactagtgtgctagaagcacatatcctacagctggacaag gccttagataccagtcgtttccaaatacagcaaacagaaaacatcatccgcagcaaaaca cctacaggaccagaactggattccagttacaagggatatatgaagctactaggtgagtgc agtggaaccatagactcggtaaaaagacttggatacaaactgaaggaggaagaggaaaaa ttatctggacttattaacctgaacagtactgaaacccaaacagctggtgtaattgaccga tgggaattaatccaggctcaagctctaagcaaggaactaaggatgaagcagaaccttcag cagtggcagcagttcaattctgaccttaatagcatttgggcttggttgggagaaactgag gaagagttggagaagctccgctgccttgatcttagtactgacatacaagccatagagttt aggattagaaagctgaaagtgagctgcagaaggcaattgataaccgcaaagcaatcattt tatccatcaatttgtgcagctcagagttcactcagtctgacagtgaagagagtaagaagc tccaagagcgcctgtcacagatga

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