KEGG   Aythya fuligula (tufted duck): 116490387
Entry
116490387         CDS       T07966                                 
Symbol
PLCB2
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
  KO
K05858  phosphatidylinositol phospholipase C, beta [EC:3.1.4.11]
Organism
aful  Aythya fuligula (tufted duck)
Pathway
aful00562  Inositol phosphate metabolism
aful01100  Metabolic pathways
aful04020  Calcium signaling pathway
aful04070  Phosphatidylinositol signaling system
aful04081  Hormone signaling
aful04082  Neuroactive ligand signaling
aful04261  Adrenergic signaling in cardiomyocytes
aful04270  Vascular smooth muscle contraction
aful04310  Wnt signaling pathway
aful04371  Apelin signaling pathway
aful04540  Gap junction
aful04621  NOD-like receptor signaling pathway
aful04912  GnRH signaling pathway
aful04916  Melanogenesis
Module
aful_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:aful00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    116490387 (PLCB2)
 09130 Environmental Information Processing
  09132 Signal transduction
   04310 Wnt signaling pathway
    116490387 (PLCB2)
   04371 Apelin signaling pathway
    116490387 (PLCB2)
   04020 Calcium signaling pathway
    116490387 (PLCB2)
   04070 Phosphatidylinositol signaling system
    116490387 (PLCB2)
  09133 Signaling molecules and interaction
   04082 Neuroactive ligand signaling
    116490387 (PLCB2)
   04081 Hormone signaling
    116490387 (PLCB2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    116490387 (PLCB2)
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    116490387 (PLCB2)
  09152 Endocrine system
   04912 GnRH signaling pathway
    116490387 (PLCB2)
   04916 Melanogenesis
    116490387 (PLCB2)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    116490387 (PLCB2)
   04270 Vascular smooth muscle contraction
    116490387 (PLCB2)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:aful04131]
    116490387 (PLCB2)
Enzymes [BR:aful01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     116490387 (PLCB2)
Membrane trafficking [BR:aful04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    116490387 (PLCB2)
 Endocytosis
  Macropinocytosis
   Phospholipase C
    116490387 (PLCB2)
SSDB
Motif
Pfam: PLC-beta_C PI-PLC-X PH_14 PI-PLC-Y PLCB1-4-like_EFh EF-hand_like C2 NAD_binding_4 VpsT-like_REC
Other DBs
NCBI-GeneID: 116490387
NCBI-ProteinID: XP_032045406
UniProt: A0A6J3D267
LinkDB
Position
5:19039471..19086296
AA seq 1211 aa
MSMLTPVLQPPEVKEYLSKGERFIKWDDETANASPVILRVDPKGFYLYWTYQNKEMEILD
ITSIRDTRVGRFAKIPKCQKLREVFNLDYPHSTFLLKTLTIVSGPDMVDLTFHNFVSYKE
NVGKSWAEDIMAIVRNPLTYNASRYTFLEKILVKLKMQLNAEGKIPVRNIFQMFPADRKR
VEAALSACHLPKGKNDAINPEDFPETVYKTFLMNLCPRPEIDEIFTSHHLKAKPYMTKEH
LAKFINKKQRDSRLNDILFPPAKPEQVQSLIEKYEPSGINIQRGQLSPEGMVWFLCGPEN
NVIALDKLVLYQDMTQPLSHYFINSSHNTYLTAGQFSGISSPEMYRQTLLAGCRCVELDC
WKGRPPDEEPIITHGFTMTTEILFKDAIEAIAESAFKTSLYPVILSFENHVDSPKQQAKM
AEYCRTIFGDMLLTEPLEKYPLKPGVPLPSPKDLLGKILIKNKKKQSVSGKRQNSLKKGR
NVEPELIGQPAPMDAEDTVWAGDVAEEEPEEEDEQLGNLDEEEIKKMQSDEGTAGLEVTA
YEEMSSLVNYIQPIKFDSFEVSAQKNRSYVISSFTELKAYDLLTKFPMQFVEYNKRQMSR
IYPKGTRMDSSNYMPQMFWNVGCQMVALNFQTMDVPMQQNMALFEFNGQCGYLLKHEFMR
RPDKPFDPFSVDRIDVLVASTLSVTILSGQFLSDRSVKTYVEVELFGLPRDTKRKYRTKL
TSTANSINPVWKEEPFVFEKIMMPELASLKIVAYEEGGKFIGHRVIPIIAVHSGYHHVCL
RSESNMPLTMPSLFVYLEVKDYVPDAWADLTIALSNPIKFFSLQDKKSVKLKDGSVERLD
MQRNFPSAESNGIPDSTGKFTTPFANGPAGAMALAKDENVIEVTQITEPQTASLAELQQM
KLFLKLLKKQEKELKELERKGSKRREELLQKYSVLFSEPIYHGGKKRAIHSRKIQKKRSL
TIADVDTTCANPVVMAESIDSQVLELKERLKMDLIQLGEEHYDGIRRRKEQHATEQVTKI
TELAKEKQTAELKALKESSESNIKDIKKKLEAKRVDRIQAMMRNTSDKAAQERLKKEINN
SHIQEVVQTIKLVIEKTARYQRKLEEKQADNLRAIKEKESQLQQEAVAEYEEKLKSLNTE
VQEIMKNCAKVVFPEEPEMWNEAVLSIPKEEQHSTEQLEEKIPVAEVSRLTIAMAEPPET
ETDGNIEESRF
NT seq 3636 nt   +upstreamnt  +downstreamnt
atgtcaatgcttacccctgtcctgcagcccccggaggtgaaggagtatctgtccaagggc
gagcgcttcatcaaatgggatgatgaaacagcaaatgcttctcctgtgattcttcgggtg
gatccaaagggcttttacttatactggacctatcagaataaggaaatggaaattctggat
atcaccagcatccgagatactcgagtagggcgatttgccaaaatccccaagtgccagaag
ctccgagaagtttttaatttggattaccctcacagcacctttctgcttaagactctgact
attgtatctggccctgacatggtggacctcactttccataactttgtgtcctacaaggaa
aatgttggcaagagctgggcagaggatattatggccatcgttcggaatcccctcacatac
aatgcttctcggtacaccttcctggagaaaatcctggtgaaactgaagatgcagcttaat
gcagagggaaagattcctgtcaggaatatttttcagatgtttcctgcagacaggaaaagg
gtggaagcagcattaagtgcttgtcatcttccaaaaggcaagaatgatgccatcaatcca
gaggactttcctgagactgtgtataaaactttcctcatgaatctgtgtccacggcctgag
attgatgagatatttacctcacaccatttaaaagcaaaaccctacatgaccaaggaacac
ttggcaaagttcatcaacaagaagcagcgagactctcgcctcaatgacatccttttccca
ccagcaaaacctgagcaggtgcagagcctgatagagaaatatgagcccagtgggattaac
atccaaagagggcagttgtctccagaggggatggtctggtttctctgtggccctgagaac
aatgtgatagcgctggataaattggtgctgtaccaggacatgacgcagccactctcacac
tacttcatcaattcatcacacaacacatatttaacagctggtcagttttctggtatctcg
tctcctgaaatgtatcgccagacactgctggctggctgtcgttgcgtagagctggattgc
tggaagggccgtcccccagatgaggagccgatcatcactcatggattcaccatgacaact
gagatcctcttcaaggatgcaatcgaggccattgcagaaagtgcttttaaaacatctctc
taccctgtcatcctgtcctttgagaaccacgtggactcgcccaagcagcaggcaaagatg
gctgagtactgccgaaccatattcggagacatgctgctgacagagccactggaaaaatac
ccactgaagccaggagttcccctgccaagtcctaaggatctcttagggaaaatcttgatt
aagaacaaaaagaaacaatctgtatctgggaagaggcagaattctttgaagaaagggagg
aatgtggaaccagaactcattgggcagccagcccctatggatgctgaagatactgtttgg
gcaggcgatgtggctgaagaggaaccagaggaagaggatgagcagctgggaaacctggat
gaagaggaaattaaaaagatgcagtcagatgagggcaccgctggtttggaagtgacagcg
tatgaggaaatgtccagcctagttaattacatacagcctatcaaatttgactcctttgaa
gtctctgcccagaagaaccggagttatgtcatctcttccttcacggaactgaaggcttat
gatctgctaaccaagttccctatgcagtttgtagaatacaacaagcgacagatgagccgg
atttaccccaaaggcacccggatggactcctctaattacatgccccagatgttctggaat
gttggctgtcagatggtggcactgaacttccagactatggatgtccccatgcagcagaac
atggctctgtttgagttcaatggccagtgtggctatctgctcaagcatgaattcatgcgg
cgtccagacaagccatttgaccctttctctgtggaccgcattgacgtgctggtggcaagt
accctgtctgtcacgatactttctggtcagttcctctcagaccgtagtgtgaagacatat
gtggaagtagagctgtttgggttgccacgggacacaaaacgcaaatacagaaccaaactg
acctccactgccaattccattaaccctgtatggaaagaggagccttttgtttttgaaaag
atcatgatgcctgagctggcatctctaaaaattgtggcttatgaagaaggagggaagttc
attggtcatcgtgtcattcccattattgcagtgcactcaggctatcaccatgtttgtctc
cgcagtgaaagcaacatgccactcactatgccttctctatttgtgtacctggaagtaaag
gattatgttcctgatgcttgggcagatctgactattgctctatccaacccgattaagttc
ttcagtctgcaagataagaagtcagttaagctaaaagatggctcagtggagaggcttgac
atgcagaggaacttcccatctgctgaaagcaatgggataccagactccactgggaaattc
accaccccttttgcaaatggacctgcaggagcaatggctttggccaaggatgaaaatgtg
atagaagtgacacagattacagagcctcagacagccagcctcgcagaactgcagcagatg
aagctctttctgaagctgctgaagaaacaggagaaggagctaaaggagctggaacggaaa
ggaagtaaacggagggaagagctgctgcagaaatattctgtcctcttttcggaacctatc
taccatggaggcaagaaaagggcaatacactccagaaaaatccagaagaagaggagtctg
acaatagctgatgttgatactacatgtgcaaatcctgtagtaatggcagaaagcatagat
agccaagttttggaactgaaagagaggttgaagatggacctcatccagctgggggaagaa
cactatgatgggattcgaaggaggaaggaacagcatgccacagagcaagttaccaagata
acggagttagccaaagagaagcagacagctgagctgaaggcactgaaggagtcatcagaa
agtaatattaaagatattaagaagaagctggaggcaaagagagtggaccgaatccaagcc
atgatgcggaatactagtgacaaggctgctcaggagaggttgaagaaagaaataaataac
tctcatattcaggaagtggtgcaaacaatcaaactggtgatagaaaaaacagccaggtat
cagcggaaactggaagagaagcaggcagataatctgagagcaatcaaggagaaagaaagc
cagcttcagcaggaggcagtggcagagtatgaggagaaattgaaaagcctgaatacagag
gtgcaggagatcatgaagaactgtgcaaaagtagtctttcctgaagagccagagatgtgg
aatgaagcagttctgagcattcctaaggaagaacaacactctacagagcaactggaagag
aagatccctgtggcagaggtgtcaaggcttacaatagctatggctgaacccccagaaact
gaaacagatggtaatattgaggaaagtagattttga

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