Anopheles funestus (African malaria mosquito): 125761955
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Entry
125761955 CDS
T09273
Name
(RefSeq) trifunctional purine biosynthetic protein adenosine-3
KO
K11787
phosphoribosylamine--glycine ligase / phosphoribosylglycinamide formyltransferase / phosphoribosylformylglycinamidine cyclo-ligase [EC:
6.3.4.13
2.1.2.2
6.3.3.1
]
Organism
afun
Anopheles funestus (African malaria mosquito)
Pathway
afun00230
Purine metabolism
afun00670
One carbon pool by folate
afun01100
Metabolic pathways
Module
afun_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
afun00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
125761955
09108 Metabolism of cofactors and vitamins
00670 One carbon pool by folate
125761955
Enzymes [BR:
afun01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.2 Hydroxymethyl-, formyl- and related transferases
2.1.2.2 phosphoribosylglycinamide formyltransferase 1
125761955
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.3 Cyclo-ligases
6.3.3.1 phosphoribosylformylglycinamidine cyclo-ligase
125761955
6.3.4 Other carbon-nitrogen ligases
6.3.4.13 phosphoribosylamine---glycine ligase
125761955
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Ortholog
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Gene cluster
GFIT
Motif
Pfam:
GARS_A
Formyl_trans_N
AIRS_C
AIRS
GARS_N
GARS_C
ATP-grasp_3
ATP-grasp
ATP-grasp_2
ATP-grasp_4
Motif
Other DBs
NCBI-GeneID:
125761955
NCBI-ProteinID:
XP_049279533
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Position
2:complement(81066214..81072059)
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AA seq
1382 aa
AA seq
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MVQDSGTLKKVLVIGGGGREHAMCWKMARSERVETVYALPGSPGIAAVPKVQLVSDVSVK
NHGSIVAWCKQNQIDLIAVGPEDPLADGLADVLLAAGIKCFGPGRRGAQIEADKNWSKDF
MHRHGIPTARYASFTDATEAKAFIRSAPYAALVVKASGLAAGKGVIVAETIDEACAAVDD
ILGEKRFGAAGEVVVVEEKLSGEEVSVLAFVDARTVRVMLPAQDHKRLQDQDRGPNTGGM
GAYCPCPIIKPAQLEMVVREVLQRAVDGLRAEGIKYNGVLYAGMMLTPNGPKTLEFNCRF
GDPETQVILPLLESDLYEVMEATCDNKLHEINLKFRAGLSAVGVVMASKGYPETSTKGCV
IKGLDAVAARPEHLVFHSGVARNECGEFVTNGGRVLIGVVLHSDLRQAAALATSACTTAI
SFDGSQHRLDIAQKAFKHQSLSYKASGVDIDAGDALVQRIKPLARGTNRPGVVGGLGGFG
GLFRLNDVVYTNREGKSVRYSDPVLVQGTDGVGTKLKLAEALNCWDTIGIDLVAMCANDV
LCAGAEPLAFLDYIACGRLEVPTAALIVKGIAEGCRETNCALLGGETAEMPSMYEKGKYD
LAGYCVGVVEHDQILPRIDRIKEGDLVIGLPSSGVHSNGFSLVNRILERTGTKLTDRAPF
SEDGCTTFGEELLTPTSLYVTPLLPLLRQSDTVKALAHITGGGLVENVPRVLPEGLAVEV
DFSDVRIPPIFGWLAAAGNVTEREMLRTFNCGIGMVVIVSENDRTWKEKLSGHGAVLLGR
VSRRARGTDQVVVKNFTQAITKVAVNYKPEKKSPTAISYKDSGVDIGAGDELVQRIKPFA
RSTNRPGVMGGLGGFGGLFRLRDTGMNLEDPILVLGTDGVGTKLKIAQDCNLHGTVGIDL
VAMCVNDIICNGADPLAFLDYYACGQLDVPVAAQVIEGIAEGCRQGHSALLGGETAEMPG
MYAKGVYDLAGFSLGIAERSKMLPRIDCICPGDVILGLPSSGVHSNGFSLVHKILEFAGH
SYNDVAPFSAMGKSFAHELLVPTRIYVRELQSLLAEGLVKALAHITGGGFTENIPRVLPA
GVAAFLDLTELHIPPIFGWLSRAGNVTADEMLRTFNCGIGMVLVVATEHKHTVLQRLRSA
GGTALGTVVKKSDPLGQRVIVQGFEDTLRLSQLTCSLPKKRIAVLISGSGSNLQALIDAT
RSSVFGIRGEIVLVVSNKAGVFGLERAAKAGIPSKVILHKDYNTRELFDAAVSQLLEKER
IELVCLAGFMRILSEGFVKRWKGALINIHPALLPRHKGIHAQRQALEAGDVESGCTVHFV
DEGVDTGAIILQERVPILRGDTEEALTERIHQAEHIAYPKALRLVANDIATLGQDGTLQW
MS
NT seq
4149 nt
NT seq
+upstream
nt +downstream
nt
atggttcaggacagtggtacgctgaagaaggtgttggtgatcggaggcggtggccgtgaa
catgccatgtgctggaagatggcccgcagtgaacgggtagaaaccgtgtacgcacttcca
ggcagccctggcattgcggccgtcccgaaggttcagctagtgtcggatgtcagcgtgaag
aaccacggttccatcgttgcctggtgcaagcagaatcagatcgatctgatagcggttgga
ccggaagatccgctagccgatgggcttgccgatgtcctgctggcggccggtataaaatgc
ttcggtcccgggcgacgcggtgcccaaattgaagcggacaaaaattggtccaaggacttt
atgcatcggcacggcattccaacggcccgttacgcaagctttaccgatgcaaccgaggcg
aaagcgtttattcgcagcgcaccgtacgcggcactggtcgtgaaggcgagtggtttggcc
gccggcaagggtgtcattgtggcggaaacgatcgacgaagcatgtgcagcggtggatgac
atactcggcgagaaacggttcggtgccgccggtgaggtggttgtcgtggaggaaaaactg
tccggcgaagaagtttccgtactagcattcgtggacgctcgtaccgtgcgcgtgatgcta
ccggcccaggatcataaacggttgcaggatcaagatcgtggtccgaataccggcggaatg
ggtgcatattgtccctgtccgatcatcaaacccgcacaactggagatggtcgtacgggag
gtgttgcagcgggccgtcgatggattgcgagcggaaggcatcaagtacaacggagttctg
tatgccggcatgatgcttacgccaaatgggccgaaaacgctcgagttcaattgccgtttc
ggtgatccagagacgcaggtcattctgcccttgcttgagagcgatctgtacgaagtaatg
gaagcgacctgtgacaataaattgcacgagatcaatcttaagtttcgcgccggtctcagt
gcagttggtgtagtgatggccagcaagggctacccggaaacctccaccaagggttgcgtt
atcaaaggacttgacgcagttgctgcacgtccggaacatctcgtgtttcattccggcgtc
gcacggaacgagtgtggcgagttcgttaccaacggtggccgagtgctgatcggtgtagtg
ctgcacagcgatctgaggcaggcagctgcactagcaacatccgcctgcacgacggcgatt
agctttgacggatcgcagcaccggctggacattgctcagaaagcattcaaacaccaaagt
ctgtcgtacaaagcgagtggcgtcgatattgacgcaggagatgctttggtgcagcgcatt
aaaccattggcccgaggaacgaatcgtccgggtgtggttggcggactcggagggtttggt
ggattattccgactaaacgatgttgtgtacactaatcgggaaggaaaatcggtccgatac
agtgacccggtgctggtacaaggtaccgatggtgttggtaccaagctgaaactcgccgaa
gcactcaactgctgggacacgatcggcatcgatctggtggcaatgtgtgcgaacgatgtg
ctatgtgccggtgcggaaccacttgccttcctggattacattgcctgcggtcggttggaa
gtaccgaccgcagccttgatcgtgaaaggaattgcggaaggctgtcgcgaaacaaactgt
gcactgctcggtggtgaaacggccgaaatgccctcgatgtacgagaagggcaagtacgat
ctggccggatactgtgtcggcgtggtagaacacgatcagatccttccgcgcatcgatcga
atcaaggagggcgatctggtgatcggtctgccatcgagcggagtgcatagcaatggattt
agcttggtcaatcgaatcctagagcgtaccggtacgaagctaaccgatcgtgcaccgttc
agtgaggacggatgtaccactttcggggaggaattgctaaccccgactagcctgtacgtg
acaccgttgctgccgctccttcgccaaagcgacacggtgaaagctttggcacacattacc
ggtggtggactggtggagaatgtcccacgtgtgcttccggaagggttggcagtcgaagtg
gactttagcgatgtgcgaattcctcccattttcggttggctagcagcggcaggaaatgta
acggagcgtgaaatgctacgcacgttcaactgtggcatcggaatggtagtgatcgtatcg
gagaatgatcgtacgtggaaggaaaagttgtccggccatggtgcggtgctacttggacgc
gttagccgacgagcgcgcggtacggatcaagtggtggtgaagaatttcactcaagcaatc
acgaaagtggcggttaactataaaccggaaaagaaatccccaaccgccatatcgtacaag
gatagtggcgttgacattggtgctggcgatgagttggtgcaaagaatcaaaccattcgcc
aggtcgaccaaccgacccggcgtaatgggtgggcttggtggttttggaggactgtttcgg
cttcgggacacgggcatgaatctcgaagatcctattctcgtgctcggtacggatggtgtc
ggtacaaagctgaagatcgcccaggactgtaacctgcacggtacggtaggcatcgatctg
gtggccatgtgcgtaaacgatatcatctgcaatggtgcggatccgctcgcttttctcgat
tattacgcttgcggtcagttggatgtgccagtagcggcacaggtaattgaaggcattgct
gaaggatgtagacagggccacagtgccctgctcggtggtgaaacggccgaaatgccggga
atgtacgcaaagggcgtatacgacttggcgggcttttcgcttggaattgcagaacggagc
aaaatgttacctcgcatcgattgcatctgtccgggcgatgttattctcgggttgccatcg
agcggagtgcacagcaatgggttcagcttggtacacaaaattctggaattcgccggccat
tcgtacaatgatgttgcaccattcagcgccatgggcaagtcgtttgcgcatgagctgctt
gtaccgacccggatttacgtacgtgagctgcagtccttgctggcggagggattggtgaaa
gccctcgcacacattaccgggggaggtttcacggaaaacatcccacgcgttctaccggcc
ggtgtggcagcattcctcgatcttaccgagctgcatattccgcccattttcgggtggctg
tcacgtgctggtaatgtaacggccgatgaaatgttgcgcacattcaactgcggcatcggt
atggtgctggtggtggccacggaacacaagcacaccgtactgcagcgtctccgaagcgcc
ggaggaactgcgctcggcacggtggtgaaaaaatcggacccactcggacagcgtgtgatt
gtgcagggtttcgaggacacgttgcgtctatcccagcttacctgttcgctgccgaagaaa
cggattgcggtgctgatttccggctccggtagcaatttgcaagcgttgattgatgccacg
cgtagttcggtgtttggaattcggggcgaaattgtgctggtagtgtcgaacaaggcaggt
gtatttgggctggaaagggctgccaaggcgggcataccttcgaaggtaatcttgcacaaa
gactacaacactcgcgagcttttcgatgcggccgtttcgcaactactggaaaaggaacgt
attgagctggtgtgtttggctggatttatgcgcattctttcggaaggattcgtgaagcgt
tggaagggtgcattgattaacattcatccggcgttactgccacgccacaagggcatccat
gcacagcggcaagcactcgaagcgggagacgtagagtcgggctgtacggtgcactttgtc
gatgaaggcgtcgatacgggagcgatcatactgcaggaacgcgtgccaattctcagaggc
gacaccgaggaagcactcaccgaacggattcaccaggcggaacacattgcgtacccgaag
gcactgcggctggtagcgaacgatattgcaacccttggacaggacggcacactacaatgg
atgagctaa
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