Anopheles funestus (African malaria mosquito): 125763290
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Entry
125763290 CDS
T09273
Name
(RefSeq) 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
afun
Anopheles funestus (African malaria mosquito)
Pathway
afun00280
Valine, leucine and isoleucine degradation
afun00640
Propanoate metabolism
afun00785
Lipoic acid metabolism
afun01100
Metabolic pathways
afun01210
2-Oxocarboxylic acid metabolism
Module
afun_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
afun00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
125763290
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
125763290
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
125763290
Enzymes [BR:
afun01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
125763290
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Motif
Pfam:
E1_dh
DXP_synthase_N
DUF6409
RNase_J_C
Motif
Other DBs
NCBI-GeneID:
125763290
NCBI-ProteinID:
XP_049282180
UniProt:
A0A182RYC7
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Position
2:complement(40032769..40034715)
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AA seq
443 aa
AA seq
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MSVVRNLGNALVKRMMIARPSRLACQVQHLSSDTATLQQGAGNSSLHAKFPGATEASFVT
IPKLALPESIDPIPIYRVMNSEGTIDDPSQEPNLEQATVQKMFRDMVLLNTMDKILYESQ
RQGRISFYMTNFGEEASHIGSAAALSPEDWVYGQYREAGVLVWRGFTISDFINQCYGNAE
DLGKGRQMPVHYGSRKLNFVTISSPLATQIPQAAGAAYAFKLQPNNQRCVITYFGEGAAS
EGDTHAAFNFAATLDSPVIFFCRNNGFAISTPSKEQYRGDGIAGRAAGYGMAALRFDGTD
VFATYNATKLAREYVLRENKPIVLEAMAYRISHHSTSDDSTAYRPADELEIWNTVEHPIT
KLKHYMIRRGWFNEEKENEFVKSVRKQVLSQISQSERIPKPDWREMFQDVYEEMPAHLKE
QLRTMEEHIEQHREHYPLKDFKQ
NT seq
1332 nt
NT seq
+upstream
nt +downstream
nt
atgtctgtggtacgtaatttgggaaatgccttggttaagagaatgatgatcgcacggcca
tctcggttggcgtgccaagtgcagcacctttcatcggacactgcgacgttgcaacaaggc
gctggaaatagttcgttgcacgcaaaattccctggcgctacggaagcatcgttcgtgacg
attcctaaattggcattgccggaaagcatcgaccccatccctatctatcgcgtgatgaac
agtgagggcacgatcgacgatccatcgcaagaacctaaccttgagcaggcaactgtgcaa
aagatgttccgcgacatggtgctactaaacaccatggacaagattttgtacgaatcccag
cgccaagggcggatatcattctacatgaccaactttggtgaagaggcaagtcacatagga
agcgcagctgctcttagtcccgaagattgggtgtacggacagtaccgagaggcaggagtg
ttggtttggcgcggatttaccatttcggatttcatcaaccaatgctatggaaacgccgag
gatcttggcaagggtcgtcaaatgccggtccactacggttcacggaaacttaactttgtc
accatttcctctccgttggccactcaaattccacaggcggctggagcggcctacgcgttc
aaactacagccaaacaaccagcggtgtgttataacgtatttcggtgaaggagctgcatct
gagggcgatactcatgcggctttcaacttcgcggctactctcgacagcccggtaatcttt
ttctgccgtaataatggatttgccatttctacgccgtctaaggagcagtatcgtggcgat
ggtattgctggacgtgccgccggttacggtatggccgcattgcgattcgatggaactgac
gtgtttgcaacgtataatgctaccaagctcgctcgagagtatgtcctgcgagagaacaaa
ccgatagtgctagaagcgatggcatatcgtatcagtcatcattctacttcggatgacagc
acggcctatcgaccagccgatgagttggaaatttggaacacagtcgagcatcccatcacc
aagcttaagcactatatgattcgacgtggctggtttaacgaggagaaagagaatgagttt
gtaaaatcagttcgcaagcaggtgctgtctcagataagccaatcggaacgcattcccaaa
ccagactggcgtgaaatgttccaggatgtgtacgaggagatgccggcacatctcaaggaa
caattgcgtacgatggaggaacacatagaacagcatcgtgagcactatccactcaaggat
ttcaaacagtag
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