KEGG   Anopheles funestus (African malaria mosquito): 125764900
Entry
125764900         CDS       T09273                                 
Name
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase epsilon-1-like isoform X1
  KO
K05860  phosphatidylinositol phospholipase C, epsilon [EC:3.1.4.11]
Organism
afun  Anopheles funestus (African malaria mosquito)
Pathway
afun00562  Inositol phosphate metabolism
afun01100  Metabolic pathways
afun04070  Phosphatidylinositol signaling system
Module
afun_M00130  Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
Brite
KEGG Orthology (KO) [BR:afun00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    125764900
 09130 Environmental Information Processing
  09132 Signal transduction
   04070 Phosphatidylinositol signaling system
    125764900
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:afun04131]
    125764900
Enzymes [BR:afun01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.11  phosphoinositide phospholipase C
     125764900
Membrane trafficking [BR:afun04131]
 Exocytosis
  Calcium ion-dependent exocytosis
   Phospholipases
    125764900
 Endocytosis
  Macropinocytosis
   Phospholipase C
    125764900
SSDB
Motif
Pfam: PI-PLC-X PI-PLC-Y RA C2 RasGEF EF-hand_like RA_2 RA_3 GDPD ANAPC_CDC26 TFIIA
Other DBs
NCBI-GeneID: 125764900
NCBI-ProteinID: XP_049285536
LinkDB
Position
2:14149233..14207188
AA seq 2146 aa
MREAFPSLPFDNITEEKLLLLLLLAARPSPTAQHEPHHDDVRRPDELTIIGEKIIINREG
ETIKQTLVDNEHDQPTLQKNAVLDTDDTAQSHAGHLPAAVLTAATAAATASTTATTSPSV
SSTTHQQHQHHQQQQQHQQQHSVAASATAAAATFSTTATTSISSSSGTAALAAAPVPFSG
ELEELQYILHFPEEVALRITDMEYQLFYQVSPVDFINEAILELKRERCGVVAGGGREGGS
IQSPFSSFISSLNPIRKRFDETSAWTNYIVLSQGTQDERKAAFACLLRVAISCWNIGNFN
GAKEIVDGLKSIKKEAFWTSATDRTGRNTVYEFLTTVFDSFEYDNAVTRALDIPTCRMIP
YFRNHVDEIKTLLLTVPQSIGPTGSDGGENPVEKYFLGEVKPLPLREDEEFIARLLPLAL
PIDCRVRTPVPTEPPDIPSDESTEPLLLSDDRDESSGVAEADREELLDQIQLRAEPAVNR
LTAFIDHHDQLCRELPHSLLEYLRAAANSPRQTKTPLYIYQPSNLQEQEEDYEVEIGNYN
PVQPLFYDHGISIIPLSSQKTNAIDHHILQILHHGTTCVLWEPETPSDRSSYVYLRLERS
CSFVSWQRTAWRRIKSQQADFSLNVNPEEIVAWKFANRYASNVGELEGQCQNLDEGMLDL
GTIKEINMGSRNHEYDAEILAAGKRFGLTHVECCVTLLYGNSASENRILCILCPPMLCRA
WYVGLNWMLRGIRRQQILIDRSMLWLKELYIQLYFEEGACSEPSVADAIKAFGGRCYGLS
SIKSWSGSQINDASETSTVAKKDSSTTKIRKKRSVVNLLNQANPTGSGGGSGGGGSGSGG
DTTPSDTMLLDTRDYRTRSIERRRERNGSNDQLWQNVKHLRIGSVTYDTQLDFLSFVSLY
RSFSLIARQDLRDIFDQLSVTTISRTTLNGEKSRSAPELSEAMVKRKIGLLTRNCSLDMD
LTEAKHTQKKYFDAIAASSIAHIAASNDFLSCSNKVITISTLKKFLETRQMEIKTDEDVK
AIIQRHEPEAAHRIENCLSFEGFARYMIDKDNYAFLSEIMPESTYMNLPMSHYYIASSHN
TYLTGHQLKGESSVELYSQVLLTGARCVELDCWDGDDGTPVIYHGHTFTTKIPFRAVVEA
INKSAFIQSSYPVILSIENHCSVQQQQRMANIFQAIFGEKLVTNFMFDQDYSDEPYLPSP
LSLKHKILIKNKKLIVEIPATLSTGLTRQNTFKQSNLSSRASSIISNTSGSSLNEEFSDD
EYEDDDDFDNIDEKTYHTTWGSIEDKYRHSVCHSNITPTKSKVQDQDERSRKRSNQIARE
LSDLVIYVQAIKFRGLNPYSPHNSIRANPKQQQQQQQQQQQSQQSQQNLPNAQQISQQQQ
NVLKTSGSVVTVGSILKNSSGDTLSLPSSSHLSDSLSLSYDASSISGSESHLPPLSNSTR
NRTLPNANHPCYQCSSINEASAKKLCRKDPLGLIAHTESQLMRTYPAGLRIDSSNFNPVF
FWSFGIQMVALNYQTEDIPMHINKAMFEENNSCGYVRKPDVLWNRSHLMYRRYSPLEKEF
DGLHVTQLVLNIVSGQYLNQSSLYSSTFVEIELLGIPVDCGKRKTKIIRKNSFNPLWNET
FYFKIMFHDLAFLKFSVYDAETGLVIAQRVISLKCIRPGYRHVRLRSPTNQPLNMASLFV
YTRVEEESLDRSYDEIDEQYLQQRGEKNRGGRGNNSGADTSDVPVLFEASRLDVVNSLES
KVPQLKRKMFFLTVYDVVPDKPYTILKITQESTTKDVLTQAMQKMNKSAQDMSNFILIEE
VYRGWEKKDRLLPPSQRVLDMTEKPLQAQGHWKGEGRFILKKIGNDPSSRAWVTSIRRTT
DRRASLAATMAGAAGGIGASGGAGSGKEPTADDLLALENVDNFLVCVYNVSQDIPYAILR
VPMKSTAQDVLAQALLKARRLDNPNNFVLVEELNYSNKSNDTMQRILLDDENVYVTQANW
KTIGRFVIHERSQLTPSTIRKTILPIEKISRGFSISRGSSSSSTSVHSLASKSPIQVALS
DPTASSSTSRFKSRSAGAHESASASGSGVGTKSRHHGHGRTKFSSEKDTSFSSTSAGNAG
SKSANRREVHSEGETLSDEETKESDIMSTMSRFKRMSIKKLKSWKS
NT seq 6441 nt   +upstreamnt  +downstreamnt
atgcgtgaagcttttccaagtcttccatttgataacattaccgaagagaagctactacta
ctactactgctagcggcccggccgagcccgacggcgcagcacgaaccgcaccacgacgac
gtacggcggccggacgagctgacgataatcggcgaaaagataataattaatcgtgagggt
gaaacaattaagcaaacattggtggataacgagcacgaccagccgacgctccagaagaat
gctgtacttgatactgacgacacagcgcaaagccacgctggccatctgccagcagcagtc
cttacggcagcaacagcagcagcaacggcgtcgacgaccgccacgacgtcaccctccgtc
agctcgacgacccatcaacagcatcagcatcatcagcagcagcagcagcatcaacagcag
cactcggtggcggcatcggccaccgcggctgccgccaccttctccaccaccgcgaccacc
tcgatctcgagcagcagcggtacagcggccctagcggcggctcccgtaccattctcgggc
gagctggaggagttgcagtacatactgcactttcccgaggaggttgcgcttcgcatcacc
gacatggagtatcagctgttctaccaggtatcgccggtagatttcataaacgaggccatc
ctcgagctgaagcgggaacggtgcggcgtggtcgctggtggtggccgagagggcggaagc
atccagtcgccttttagtagctttatatcgtcactgaatcccatacgcaaacgattcgat
gagaccagcgcgtggaccaactatattgtgctctcacaaggtacacaagacgaacgaaaa
gcggcctttgcatgtctgttgcgtgttgctatttcatgctggaatatcggaaacttcaat
ggtgctaaagagatagtggatggtctgaaatcaatcaaaaaggaagcattctggacgtcg
gccacggatcgtacgggacggaatacggtgtacgagtttcttacgaccgtgttcgatagc
ttcgagtatgataatgcggttacgcgggctctggacatacccacgtgccgtatgataccg
tacttccggaaccacgtcgatgagatcaaaaccctgctactgaccgtaccacagtccatc
ggcccaaccggttcggacggtggtgagaacccggtcgagaagtacttcctcggtgaggtg
aaaccgcttccactgcgggaagatgaagagttcattgcgagactgctgccactggcgtta
ccgatcgattgccgagtgcggacaccggttcccaccgaaccaccggacatcccgtcggat
gaatcgaccgaaccgttgctactgtccgacgaccgcgatgagtcgtccggtgtggcggaa
gcagatcgtgaggagctgctcgaccagatacagctacgggcggaaccggccgttaatcgg
ctaaccgcattcatcgaccaccatgatcagctgtgccgggagttaccgcacagcctactg
gagtacctacgggcggcggccaacagtccgcgccaaacgaaaaccccactctacatctac
cagccctcgaacctgcaggaacaggaggaggactacgaggtggagatcggtaactataat
ccggtgcagccactattttacgaccacgggatcagcatcataccgctctcgtcccagaaa
accaatgccatcgatcatcacatactgcagattctacaccatggtaccacgtgtgtactc
tgggaaccggagacaccgtcggatcggtcgtcctacgtatacctgcggctggagcgctcc
tgttcgttcgtttcgtggcaaaggacggcctggcggcgtattaaatcccaacaagcagac
tttagccttaacgtcaacccggaggagatagtggcgtggaagtttgccaatcgctatgca
tcgaatgtcggcgagctggaaggccagtgccagaatctggacgagggtatgctggatctc
ggcacgataaaggaaatcaatatgggctcgcggaaccacgagtacgatgcggagatactg
gcggccggcaagcgcttcggtctaacgcatgtcgagtgctgcgtgacgctgctgtacggt
aactcggccagcgaaaaccggatactgtgcatcctctgtccgccgatgctttgccgggcg
tggtacgttgggctgaattggatgctgcgcggtattcggcggcagcagatactgatcgac
cggtcaatgctgtggctgaaggaactctacatccagctgtacttcgaggaaggtgcctgc
agtgaaccgagcgtggccgatgccatcaaagcattcggtggccgctgttacgggctatcg
tccatcaagtcgtggtccggttcacagattaacgatgcgagcgaaaccagtaccgtcgca
aagaaggattcgtcgacgaccaaaatacgcaagaagcggtccgtcgtcaatttgctgaac
caagcaaaccccaccggtagtggcggcggaagcggaggcggtggtagtggcagtggaggc
gacacaacaccctccgatacgatgttgctggatacgcgcgactaccggacgcggtctatc
gagcgacgccgcgaacggaatggctcgaacgatcagctctggcagaatgtgaagcatctt
cgcatcgggtcagttacctacgatactcaattagattttttaagcttcgtttcactgtat
cgatcgtttagtttaattgcacggcaggacctgcgtgatattttcgaccagctctcggtg
accaccatatcgaggacgacgctgaacggggagaaaagccgtagtgcaccagagctatcg
gaagctatggtcaagcgaaagatcggacttttgacacgcaattgctcactggacatggat
ctgaccgaggcgaagcacacgcagaagaagtatttcgacgcaatagcagcctcaagcatc
gcccacattgctgctagcaacgatttcctttcgtgcagcaacaaagtcatcacgatatcg
acgctgaaaaagtttctcgaaacgcgccagatggaaatcaaaaccgatgaggatgtgaaa
gccattatacagcgacacgaaccggaagcggcacatcgcattgagaactgtctcagcttt
gagggattcgcccggtacatgatcgacaaggacaactacgcatttctcagcgaaatcatg
ccggaaagcacctacatgaacctgccgatgtctcactattacattgcgtcctcgcacaat
acgtacctcaccgggcatcagctaaagggtgaaagctcggtcgagctgtacagtcaggtg
ctgctaacaggtgcacgctgcgttgaacttgattgctgggatggtgacgatggtacaccg
gtcatctaccatgggcacacgttcaccacgaagattcccttccgagccgtcgtagaagca
ataaataaatctgccttcattcaatcttcctaccccgtgatactttccatcgagaaccac
tgctcggtgcagcaacagcaacggatggccaacatatttcaggcaatcttcggtgagaag
ctggtgactaactttatgttcgatcaggactatagcgatgaaccatacctgccgtcgccg
ctttcgctcaagcacaagatactgatcaaaaacaaaaagcttatagtcgaaataccggca
accttatcaaccggtttaacacgacagaacaccttcaaacaatcgaatttatccagcaga
gccagttcaattatatcaaacactagcggtagttcgctgaatgaagagtttagcgatgac
gagtatgaggatgatgacgattttgacaatattgatgaaaaaacatatcatacaacttgg
ggatcaatagaagataagtataggcatagtgtgtgccattccaacatcacgccgacaaag
tcgaaagtccaagaccaagacgaacgatcccgcaagcgcagcaaccagattgcccgagag
ctctccgacctggtgatttacgtgcaagcaataaaatttcgcggcctgaacccctacagt
ccgcacaactcaatacgtgccaatccgaagcagcagcagcagcagcagcaacagcagcaa
cagagtcaacaaagccagcagaatctgcccaatgctcagcaaatatcccaacagcagcag
aatgtgctgaaaacaagcggctcggtcgtgacggttggaagcatactgaagaacagttcc
ggcgacacgcttagtttgccctcgtccagtcatctgtcggacagtctgtcgctgagctac
gatgcgtccagcatcagtggaagcgaatcgcatctgccaccgctatcgaactcgactcgg
aatcgaaccctaccgaacgccaaccatccctgctaccagtgttcctcgatcaacgaggct
agtgcgaaaaagctctgccggaaagacccgctagggctgatcgcccacacagaatcgcag
ctgatgcgtacctatccggccggcctgcggatagactcgtccaactttaatccggtgttt
ttctggtcgttcggcatacagatggtggcgctcaactaccagacggaggacattcccatg
cacatcaacaaagcgatgtttgaggaaaacaatagctgcgggtacgtgcgcaaaccggac
gtactgtggaaccggtcgcatctcatgtaccggcggtacagtccgttggagaaggagttc
gatggtttgcacgtgacacagctcgtgctgaacattgtatcgggtcagtacctcaaccag
tccagcctatactcgagcacgttcgtcgaaatagagctgctcggaataccggtggactgt
ggcaagcgcaagacgaagatcatccgcaagaactcgttcaacccgctctggaacgaaacg
ttctacttcaagatcatgtttcacgatctagcgttcctgaagtttagcgtgtacgatgcc
gaaacggggctcgttatagcgcagcgagtaatatcgctaaaatgtatccggccaggatat
cggcatgtacggctccgttcgcccaccaaccaaccgctcaacatggcctcgctgttcgtt
tacacgcgcgtggaggaagaaagcctggaccgatcgtacgatgagatcgacgagcagtac
ctgcagcagcggggtgagaaaaaccgcggaggtcgtggaaataatagtggagccgacact
agcgatgtgcccgtactgtttgaggcgagccgactggacgtcgtcaacagtctggagagc
aaggtgccccagctgaagcggaaaatgttttttctcaccgtgtacgacgtggtgcccgac
aagccgtacacgatcctaaagatcacacaggaaagcacaacgaaggacgtgctgacgcag
gcgatgcaaaagatgaacaagtcggcccaggacatgtccaacttcatactgatcgaggag
gtgtaccgaggttgggagaagaaagatcgcctgctcccaccgagccagcgcgtactcgat
atgacggagaaaccgctgcaggcgcagggtcactggaagggtgagggacgcttcattctg
aagaagatcggcaacgatccgagcagccgggcgtgggttacttccattcggcggacgacc
gatcggcgtgcatcgctcgcggccaccatggcgggtgcggccggtggtatcggcgcgtct
ggcggtgccggcagcggaaaggaaccgaccgcggacgatctgcttgcgctcgagaacgtg
gacaactttctcgtgtgcgtgtacaacgtgtcgcaagacatcccgtacgcgatattgcgc
gtaccgatgaaatccaccgcacaggacgtgctggcacaggcactgctgaaggcgcgccga
ctcgacaaccccaacaacttcgtactggtggaggagctcaactacagcaacaagagtaac
gacacgatgcagcgcatcctgctggacgacgagaatgtgtacgtgacgcaagccaactgg
aaaacgatcggacgcttcgtcatccacgagcgcagccagctaacgccatcgacgatccgc
aaaacgatcctaccgatcgagaagatcagccgcggattcagcatcagtcgcggatcttcg
tcctcctctacctcggtgcactcgttggcttccaagtcaccgatacaggtggcgctgagt
gatcccaccgcatcttcgtctacgtcccggtttaaatcgcgttcggccggtgcgcacgag
tcagcgtccgcatccgggtcgggtgtggggaccaagtcgcgccaccacggacacggtcgg
acaaagttcagctcggaaaaggatacatccttctccagcaccagcgccggcaatgccggg
tccaagtcagccaacaggcgggaagttcactccgagggtgaaacgctcagtgacgaggaa
acgaaggaatccgacatcatgtccacgatgtcgcgcttcaaacgcatgtctatcaagaag
ctaaagtcctggaaatcctaa

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