Anopheles funestus (African malaria mosquito): 125766079
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Entry
125766079 CDS
T09273
Name
(RefSeq) DNA topoisomerase 3-alpha
KO
K03165
DNA topoisomerase III [EC:
5.6.2.1
]
Organism
afun
Anopheles funestus (African malaria mosquito)
Pathway
afun03440
Homologous recombination
afun03460
Fanconi anemia pathway
Brite
KEGG Orthology (KO) [BR:
afun00001
]
09120 Genetic Information Processing
09124 Replication and repair
03440 Homologous recombination
125766079
03460 Fanconi anemia pathway
125766079
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
afun03032
]
125766079
03400 DNA repair and recombination proteins [BR:
afun03400
]
125766079
Enzymes [BR:
afun01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.1 DNA topoisomerase
125766079
DNA replication proteins [BR:
afun03032
]
Eukaryotic type
DNA Topoisomerases
125766079
DNA repair and recombination proteins [BR:
afun03400
]
Eukaryotic type
DSBR (double strand breaks repair)
HR (homologous recombination)
Bloom's syndrome complex (BTR)
125766079
FA (Fanconi anemia) pathway
125766079
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
Topoisom_bac
Zn_ribbon_GRF
Toprim
Zn_ribbon_Top1
Zn_ribbon_GRF_2
Motif
Other DBs
NCBI-GeneID:
125766079
NCBI-ProteinID:
XP_049287627
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All DBs
Position
2:61752602..61756556
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AA seq
1004 aa
AA seq
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MLRLAKASISLIKLCSPSRALATECRTKMKYLNVAEKNDAAKTIAGLLSRGSSQRREGYS
PYNKIYEFSYNLHGQNIQMIMTSVSGHLLTHEFLPSFRGWQSCNPEDLFDAPVRKRCPEQ
FEKIKKTLEREVRGCSALIIWTDCDREGENIGFEIIEVCRAVKPQLRVLRAKFSEITAPS
IKRAVENLIQPDARQNDAVNVRSELDLRIGAAFTRYQTLRLQKAFPQDISNNLVSYGSCQ
IPTLGFVAQRYKEIENFIPQPFWKIKLTHTINELTVEFHWSRNRLFDKQCCEAYLMLCQN
NPVAKVVNVTQKPKNKWRPTPMDTVELEKLGSRKLKMNAKQVMTIAEKLYTQGIISYPRT
ETNMFTGDMKLAPLVQAQVSSDKWGAFAGKVLQWGVNPRNGKKSDQAHPPIHPTKLPTNL
SGDEWRVYELIARHFLACVSRDATGSETIVNVIVGEEEEFTASGLCIHERNYLEVYPYDH
WNAKEIHSYQVGHMFEATELGLHEGSTTAPNMLTEADLIALMEKHGIGTDATHAEHINTI
KERGYIGERDRGFLVPGTLGMGLVEGYEMMELRLAHPELRAGLEVDLKLVCEGRKNANDV
LTEQISKYKEVYRIMSQKARALDRALGQRLNQTPRDPPPDGGGVSVTAAAPMREVCKCPK
CGSKMCLRSKRDSSGYYLGCIAFPECRNNVWFDDTIREINVLDDTCPRCGSKKISVKFRS
ARFYALLQSADMEEYRFCIVCDDKFRNLFNINESSVRVVERANTTSNVAPVPVVAQSAPS
IPAGSWGSGNLSERRPSQTSNSSSSGMGRSNTSTAGSNSWGTGHSTSTSNNWGGSQSSNR
GGSTSTWGKPANNRNDGPVHRGSGFGDGGTRENAWKNTSNTSWNAADDNADVMCRCGTPA
SRFTVKKDGPNKGRPFFSCPNQASSCGFFKWGDENMPPASTNGSSAGGSISWGSGGVNTS
GSSWGRSSNDTTNKTSKTARKCGICRQEGHTKNKCPQRGDSTDF
NT seq
3015 nt
NT seq
+upstream
nt +downstream
nt
atgttacgattagcaaaagcctcaatttccttgataaaactttgttccccatctcgcgcc
ttagctactgaatgtagaaccaaaatgaaatatttgaacgtggcggaaaaaaacgatgca
gcgaaaacgattgccggtttgttatcgcgtggttcatcgcaaaggcgagaaggctattcg
ccgtacaacaaaatttacgaattcagctacaatctacacgggcaaaacattcaaatgata
atgacatccgtatcgggccatctgttgacacacgaattcctaccgagctttcgtggatgg
cagagctgcaatccggaggatctgttcgatgccccggtacggaaacgctgtccggaacag
tttgagaaaattaagaaaacactcgaacgggaggtacgcggatgctctgcactcatcatt
tggaccgattgcgatcgagaaggtgaaaacattggcttcgagataatagaggtgtgtcga
gcggtaaaaccacagttacgggttttacgggcgaagttttccgaaatcaccgccccatcg
attaagcgtgccgtcgaaaatctgatccagcccgatgctcgacaaaacgatgcggttaat
gtgcgcagtgagctcgatttgcgaatcggtgccgcttttacccgctatcagacgttgcga
ttgcagaaagcttttccacaagacatatcgaacaatcttgtgtcgtacggtagctgccag
ataccaacactaggttttgtagcgcaacgctataaggaaatagaaaatttcataccacaa
ccgttttggaaaataaaactgacgcacacgatcaatgaattaacagtcgagtttcattgg
tcacgaaatcgtcttttcgacaagcaatgctgcgaggcatatttgatgctgtgtcaaaac
aatccggttgcgaaggtcgtgaacgttacccagaagccgaagaacaagtggcgcccaaca
ccaatggacacagtggagctagagaagttaggttcgcgtaagctcaagatgaacgccaaa
caagtgatgactattgcagagaaattgtatacacaaggtataatcagttacccccgtacc
gaaacgaatatgtttaccggcgacatgaagttagccccgctagtacaggcccaggtcagc
agcgataagtggggcgcatttgctggaaaagtgctccaatggggcgtcaatccaaggaat
ggtaaaaagtccgatcaagcccatccccctatacatccgaccaaacttccgactaacctg
tccggtgatgaatggcgcgtgtatgagctgattgcacggcactttctcgcttgtgtcagt
cgcgatgcaaccggttcggaaacaatcgtcaatgtgatcgtcggtgaggaggaagaattt
accgcatcgggactgtgcatccacgagcgaaattatctcgaggtatatccgtacgatcac
tggaacgcgaaggaaatacattcgtaccaggttgggcacatgttcgaagcgaccgagctg
ggtcttcacgagggctcaacgacggcaccgaatatgctgaccgaggctgatctgattgca
ctgatggaaaaacatggcatcggtactgacgcaacgcacgccgaacacatcaacacgatc
aaggagcgcggctatatcggtgagcgtgatcgtggctttttggttcccggtacactcggt
atggggctggtggaaggttacgaaatgatggaattgcgtctggcccatcccgagctgcga
gccggtctcgaagtcgaccttaagctggtgtgcgaaggccgtaaaaatgctaacgatgta
ctaacggaacagatttccaagtacaaggaggtgtaccggattatgtcccagaaggcacga
gcactcgatcgtgcgttgggacagcggctaaatcaaacaccacgggatccaccaccagat
ggtggcggtgtatccgtaacagcagcggctccaatgagggaagtctgcaaatgcccaaaa
tgtggtagtaagatgtgccttcgaagcaagcgtgattcttccgggtactacctcggatgc
attgctttcccagagtgtaggaacaatgtatggttcgacgatacgatacgtgaaatcaac
gtactggatgatacgtgtcctcgctgtggaagcaagaagatatccgtgaagttccgcagt
gcacgcttttatgcgttattgcaaagtgcggacatggaagagtatcgtttctgcatcgtg
tgtgatgacaaattccgaaatttattcaacattaacgaatccagcgtgcgtgtggttgaa
cgtgcgaacacgacctcaaacgtcgcgcccgtacccgtggtcgcacaatctgcgcccagc
attccggcaggttcttggggctctggcaacttatcggaacgccgaccatcacaaacgtcc
aactcaagcagcagcggaatgggacgatcgaacacgagcacagcaggcagcaactcctgg
ggaacaggacattctactagcacctcgaacaactggggtggaagtcaatcatctaatcgt
ggtggatcaacatctacctgggggaaaccggcaaacaatcgaaacgatggtccagtgcat
cggggtagtggatttggagatggaggaactagagaaaacgcttggaaaaatacatccaac
acttcatggaatgctgccgatgataatgccgatgtaatgtgccgctgtggtacgccagca
tcacgctttaccgtgaagaaggatggccccaataagggaagaccgtttttttcatgtccc
aatcaggccagctcgtgtggcttctttaaatggggtgatgaaaatatgcctcccgcgtca
acgaatgggtcttccgctggtgggtcaattagttggggctctggaggagtaaacacgagt
ggttccagctggggacgcagtagcaacgacactacgaataaaacatcaaaaacggctcga
aaatgtggtatctgtagacaggaaggacataccaaaaacaaatgcccacaacgaggtgac
tcgacagatttttga
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