Anopheles funestus (African malaria mosquito): 125770469
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Entry
125770469 CDS
T09273
Name
(RefSeq) probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
afun
Anopheles funestus (African malaria mosquito)
Pathway
afun00010
Glycolysis / Gluconeogenesis
afun00020
Citrate cycle (TCA cycle)
afun00620
Pyruvate metabolism
afun00785
Lipoic acid metabolism
afun01100
Metabolic pathways
afun01200
Carbon metabolism
afun01210
2-Oxocarboxylic acid metabolism
Module
afun_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
afun00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
125770469
00020 Citrate cycle (TCA cycle)
125770469
00620 Pyruvate metabolism
125770469
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
125770469
Enzymes [BR:
afun01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
125770469
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Motif
Pfam:
E1_dh
DXP_synthase_N
HEAT_MROH2B_1st
Motif
Other DBs
NCBI-GeneID:
125770469
NCBI-ProteinID:
XP_049296110
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All DBs
Position
3:26986400..26988962
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AA seq
418 aa
AA seq
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MGLSKWVNTIFRSSKAAAAATEAIKTNNTSSSSGVENKAKTLSSQQQNGFASEATFETRA
FKLHNLEEGPSTKVTLTKEDALKYYGQMYMIRRMETAAGNLYKEKVIRGFCHLYSGQEAC
AVGMRAAMRPEDSCITAYRCHGWTYLMGVAPQAVLSELTGRSSGCARGKGGSMHMYGRNF
YGGNGIVGAQVPLGVGIGFAAKYNGTKGACIALYGDGAANQGQLFEVYNMAKLWNTPCIF
VCENNGYGMGTSVERASANTNYYTRGDFVPGIWVDGMDVLAVREATRFALEHTSSGKGPI
LMETATYRYSGHSMSDPGTSYRSRDEIAEVRQTRDPITSLREKILTTELASVEELKEIEG
KIRAEVDSATKLAKSDKEISVEELTADIYANPQNLTTVRNTLPLAELAHKRLGPAVNM
NT seq
1257 nt
NT seq
+upstream
nt +downstream
nt
atgggattgtctaaatgggtgaacacaatcttccggtcgagcaaagcggctgcggccgct
accgaagcaatcaaaacgaataacacgagcagttccagcggtgttgagaataaagcgaaa
acactttcaagccagcagcagaatggattcgcctcggaagctacgtttgagacacgggct
ttcaagctgcataaccttgaagaaggtccatcgactaaggtgaccctcacgaaagaggat
gccctaaaatactacggccagatgtacatgatccggcgcatggaaacggccgctggcaat
ctgtacaaggaaaaggtgatcagagggttctgtcatctgtactctgggcaagaggcgtgc
gccgtcggaatgcgtgccgctatgcgtccggaggattcttgcatcaccgcttaccgctgc
cacggatggacgtatctgatgggtgttgcgccgcaggccgttctatcggaactgactggc
cgaagcagtggctgtgcacgaggcaagggtggcagtatgcacatgtacggtagaaacttt
tacggtggaaatggcatcgtcggagcgcaggttccgctgggcgtgggaattggattcgct
gccaagtacaacggcacgaagggagcatgtattgcgctgtacggcgacggtgctgccaac
cagggtcagctgtttgaggtgtacaatatggccaagctgtggaacacaccgtgcattttc
gtctgcgagaacaacggctacggcatgggtacgagcgttgagcgcgcgtcggccaacacc
aactactacacgcggggagactttgtgcccggaatttgggtcgacggtatggacgtgctg
gccgtccgtgaagctacccggtttgcgttggaacatacctcgtccggcaagggtccgatc
ctgatggaaacggccacctaccgatactctggccattcgatgtccgatccgggcactagc
tatcgttcgcgagacgaaattgcagaagtaagacaaacgagagatccgataacatcgcta
cgcgagaagattttgaccaccgagctggcctcggtggaggagctgaaggagattgaggga
aagatacgggcggaggtagactcggcaaccaagttggccaagtcggacaaagaaatctcc
gtcgaggagctcaccgcagatatttacgcgaacccacaaaacctgacgaccgtacgcaac
acgctgccgcttgcggaactcgcgcacaagagattgggaccggccgtcaacatgtaa
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