Acidihalobacter ferrooxydans: BW247_07465
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Entry
BW247_07465 CDS
T09791
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
afy
Acidihalobacter ferrooxydans
Pathway
afy00790
Folate biosynthesis
afy01100
Metabolic pathways
afy01240
Biosynthesis of cofactors
Module
afy_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
afy00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
BW247_07465
Enzymes [BR:
afy01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
BW247_07465
6.3.2.17 tetrahydrofolate synthase
BW247_07465
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GFIT
Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
MarR_2
Motif
Other DBs
NCBI-ProteinID:
APZ42949
UniProt:
A0A1P8UGK8
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Position
1577635..1578897
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AA seq
420 aa
AA seq
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MNRPRFDTLPAWLEWQQSLSLKEIVLGLERVRTVGARLELLHPSCPVITVGGTNGKGSVI
ALLEAMLRAEGYKVGAFTSPHLLRYNERVRIAGVDVDDALFCQAFDAIDQARDDLPLTYF
EFGTLAALSIFATQAVDIMLLEVGMGGRLDAVNAIDADVAVVTTVDIDHAEWLGSDRESI
GREKAGILRATRPAICGDRQPPASLCEYAQQIGARLSVLGRDFEACPSENGMVWQAGGMR
RELPLPALSGAFQLDNAATALAALDALAPRLPLTDAAYAHGLRTAHVAGRYQRLPGPPPM
VCDVAHNPQAARALASILRADPVPGRNLMVFSALADKDIPAIASALDTVAGHWFVAGLDA
PRGLTADDVAERLGTVRAGVSRYVDVATALAAARASAASGDRVVVCGSFLTVAVALSAGL
NT seq
1263 nt
NT seq
+upstream
nt +downstream
nt
ttgaacaggcctcggttcgacacgctgccggcgtggcttgaatggcagcaatccctgtcg
ctgaaggaaatcgtgctcggcctggagcgtgtgcgaactgtcggtgcgcggctggagctt
ctgcatccctcctgccccgtgatcacggtcggcgggacgaacggcaagggttccgttatc
gcgctgctggaggccatgctgcgtgccgagggctacaaggtcggcgcgttcacctcgccg
cacctgctgcgctacaacgagcgggtgcggattgccggggtggatgtggacgacgcgctt
ttctgtcaggccttcgacgccatcgatcaggcccgcgatgacctgccgttgacttatttc
gagttcggcacgctggcggcgctgtccatcttcgccacgcaggcggtcgacattatgctg
cttgaagtggggatgggtgggcggctggatgcggtcaatgccattgacgccgatgtggcg
gtggtcacgacggtggatattgaccatgccgaatggctgggcagtgaccgcgagagcatc
gggcgcgagaaggccggtattctgcgcgcaacgcggccggctatttgtggcgaccgtcag
ccgccggcttcgctgtgcgagtatgcgcagcagatcggagcgcgcctgagcgtgcttggc
cgggacttcgaggcgtgtccgtctgagaatggcatggtctggcaggcaggcggaatgcgc
cgcgaattgccgctgcccgccttgtcgggcgcctttcaattggacaatgcggcgaccgcg
ctggctgcactggatgcgcttgcgccgcgcctgccgctcactgacgcggcgtatgcacac
ggcttacgcacggctcatgtagccggacgttaccaacgattgcccggcccgccgccgatg
gtatgcgatgtcgcgcataatccgcaggcggcccgcgcgctggcctcgattctgcgtgcg
gaccctgtgcccggcaggaatctgatggtgttctcggccctggctgacaaggatattccg
gctatcgcgtccgcgctcgacaccgttgccggacactggttcgttgccgggcttgatgcg
ccgcgtggtctgacggcggatgacgtagccgaacgactcggcacggtgcgggcaggggtg
agccggtatgtcgatgtggcgaccgcgttggccgccgctcgcgcaagcgcagcgtccggc
gaccgcgtcgtggtttgcggatcgttcctgaccgtggcggttgccctgtcggccggccta
taa
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