KEGG   Antechinus flavipes (yellow-footed antechinus): 127542137
Entry
127542137         CDS       T08818                                 
Name
(RefSeq) mitogen-activated protein kinase 10 isoform X1
  KO
K04440  mitogen-activated protein kinase 8/9/10 (c-Jun N-terminal kinase) [EC:2.7.11.24]
Organism
afz  Antechinus flavipes (yellow-footed antechinus)
Pathway
afz01522  Endocrine resistance
afz04010  MAPK signaling pathway
afz04012  ErbB signaling pathway
afz04014  Ras signaling pathway
afz04024  cAMP signaling pathway
afz04068  FoxO signaling pathway
afz04071  Sphingolipid signaling pathway
afz04137  Mitophagy - animal
afz04140  Autophagy - animal
afz04141  Protein processing in endoplasmic reticulum
afz04210  Apoptosis
afz04215  Apoptosis - multiple species
afz04217  Necroptosis
afz04310  Wnt signaling pathway
afz04380  Osteoclast differentiation
afz04510  Focal adhesion
afz04530  Tight junction
afz04620  Toll-like receptor signaling pathway
afz04621  NOD-like receptor signaling pathway
afz04622  RIG-I-like receptor signaling pathway
afz04625  C-type lectin receptor signaling pathway
afz04657  IL-17 signaling pathway
afz04658  Th1 and Th2 cell differentiation
afz04659  Th17 cell differentiation
afz04660  T cell receptor signaling pathway
afz04664  Fc epsilon RI signaling pathway
afz04668  TNF signaling pathway
afz04722  Neurotrophin signaling pathway
afz04723  Retrograde endocannabinoid signaling
afz04728  Dopaminergic synapse
afz04750  Inflammatory mediator regulation of TRP channels
afz04910  Insulin signaling pathway
afz04912  GnRH signaling pathway
afz04914  Progesterone-mediated oocyte maturation
afz04917  Prolactin signaling pathway
afz04920  Adipocytokine signaling pathway
afz04926  Relaxin signaling pathway
afz04930  Type II diabetes mellitus
afz04931  Insulin resistance
afz04932  Non-alcoholic fatty liver disease
afz04933  AGE-RAGE signaling pathway in diabetic complications
afz04935  Growth hormone synthesis, secretion and action
afz04936  Alcoholic liver disease
afz05010  Alzheimer disease
afz05012  Parkinson disease
afz05016  Huntington disease
afz05017  Spinocerebellar ataxia
afz05020  Prion disease
afz05022  Pathways of neurodegeneration - multiple diseases
afz05132  Salmonella infection
afz05133  Pertussis
afz05135  Yersinia infection
afz05142  Chagas disease
afz05145  Toxoplasmosis
afz05152  Tuberculosis
afz05161  Hepatitis B
afz05162  Measles
afz05166  Human T-cell leukemia virus 1 infection
afz05167  Kaposi sarcoma-associated herpesvirus infection
afz05169  Epstein-Barr virus infection
afz05170  Human immunodeficiency virus 1 infection
afz05171  Coronavirus disease - COVID-19
afz05200  Pathways in cancer
afz05208  Chemical carcinogenesis - reactive oxygen species
afz05210  Colorectal cancer
afz05212  Pancreatic cancer
afz05231  Choline metabolism in cancer
afz05415  Diabetic cardiomyopathy
afz05417  Lipid and atherosclerosis
afz05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:afz00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04141 Protein processing in endoplasmic reticulum
    127542137
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    127542137
   04012 ErbB signaling pathway
    127542137
   04014 Ras signaling pathway
    127542137
   04310 Wnt signaling pathway
    127542137
   04668 TNF signaling pathway
    127542137
   04068 FoxO signaling pathway
    127542137
   04071 Sphingolipid signaling pathway
    127542137
   04024 cAMP signaling pathway
    127542137
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    127542137
   04137 Mitophagy - animal
    127542137
  09143 Cell growth and death
   04210 Apoptosis
    127542137
   04215 Apoptosis - multiple species
    127542137
   04217 Necroptosis
    127542137
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    127542137
   04530 Tight junction
    127542137
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    127542137
   04621 NOD-like receptor signaling pathway
    127542137
   04622 RIG-I-like receptor signaling pathway
    127542137
   04625 C-type lectin receptor signaling pathway
    127542137
   04660 T cell receptor signaling pathway
    127542137
   04658 Th1 and Th2 cell differentiation
    127542137
   04659 Th17 cell differentiation
    127542137
   04657 IL-17 signaling pathway
    127542137
   04664 Fc epsilon RI signaling pathway
    127542137
  09152 Endocrine system
   04910 Insulin signaling pathway
    127542137
   04920 Adipocytokine signaling pathway
    127542137
   04912 GnRH signaling pathway
    127542137
   04914 Progesterone-mediated oocyte maturation
    127542137
   04917 Prolactin signaling pathway
    127542137
   04926 Relaxin signaling pathway
    127542137
   04935 Growth hormone synthesis, secretion and action
    127542137
  09156 Nervous system
   04728 Dopaminergic synapse
    127542137
   04723 Retrograde endocannabinoid signaling
    127542137
   04722 Neurotrophin signaling pathway
    127542137
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    127542137
  09158 Development and regeneration
   04380 Osteoclast differentiation
    127542137
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    127542137
   05208 Chemical carcinogenesis - reactive oxygen species
    127542137
   05231 Choline metabolism in cancer
    127542137
  09162 Cancer: specific types
   05210 Colorectal cancer
    127542137
   05212 Pancreatic cancer
    127542137
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    127542137
   05170 Human immunodeficiency virus 1 infection
    127542137
   05161 Hepatitis B
    127542137
   05171 Coronavirus disease - COVID-19
    127542137
   05162 Measles
    127542137
   05167 Kaposi sarcoma-associated herpesvirus infection
    127542137
   05169 Epstein-Barr virus infection
    127542137
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    127542137
   05135 Yersinia infection
    127542137
   05133 Pertussis
    127542137
   05152 Tuberculosis
    127542137
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    127542137
   05142 Chagas disease
    127542137
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    127542137
   05012 Parkinson disease
    127542137
   05016 Huntington disease
    127542137
   05017 Spinocerebellar ataxia
    127542137
   05020 Prion disease
    127542137
   05022 Pathways of neurodegeneration - multiple diseases
    127542137
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    127542137
   05418 Fluid shear stress and atherosclerosis
    127542137
   05415 Diabetic cardiomyopathy
    127542137
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    127542137
   04936 Alcoholic liver disease
    127542137
   04932 Non-alcoholic fatty liver disease
    127542137
   04931 Insulin resistance
    127542137
   04933 AGE-RAGE signaling pathway in diabetic complications
    127542137
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    127542137
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:afz01001]
    127542137
Enzymes [BR:afz01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     127542137
Protein kinases [BR:afz01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   127542137
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kdo ABC1 RIO1 Kinase-like APH FTA2
Other DBs
NCBI-GeneID: 127542137
NCBI-ProteinID: XP_051823657
LinkDB
Position
6:157214323..157388526
AA seq 464 aa
MSRYFLSYFGEPTFDVKIAFCQGFDKQVDVSYIAKYYNMSKSKVDNQFYSVEVGDSTFTV
LKRYQNLKPIGSGAQGIVCAAYDAVLDRNVAIKKLSRPFQNQTHAKRAYRELVLMKCVNH
KNIISLLNVFTPQKSLEEFQDVYLVMELMDANLCQVIQMELDHERMSYLLYQMLCGIKHL
HSAGIIHRDLKPSNIVVKSDCTLKILDFGLARTAGTSFMMTPYVVTRYYRAPEVILGMGY
KENVDIWSVGCIMGEMVRHKILFPGRDYIDQWNKVIEQLGTPCPEFMKKLQPTVRNYVEN
RPKYAGLTFPKLFPDSLFPADSEHNKLKASQARDLLSKMLVIDPAKRISVDDALQHPYIN
VWYDPAEVEAPPPQIYDKQLDEREHTIEEWKELIYKEVMNSEEKTKNGVVKGQPSPSGAA
VNSSESLPPSSSVNDISSMSTDQTLASDTDSSLETSAGPLGCCR
NT seq 1395 nt   +upstreamnt  +downstreamnt
atgagccgctacttcttgtcctacttcggtgaacctaccttcgatgtgaaaattgccttt
tgtcagggatttgataaacaagtggatgtgtcatatattgccaaatattacaacatgagc
aaaagcaaagtagacaaccagttctacagtgtagaagtgggagattcaacattcacagtt
ctcaaacgctaccagaatctaaagcctattggctctggggctcagggaatcgtttgtgct
gcgtatgatgctgtccttgacagaaatgtggccattaagaagctcagcagaccatttcag
aaccaaacacatgcaaaacgagcttacagggagctagtcctcatgaagtgtgtgaatcat
aaaaatattatcagtttattaaatgtcttcacaccacagaaatcactggaagaatttcaa
gatgtttaccttgtgatggaactgatggatgcaaacttgtgtcaggtaattcaaatggaa
ttggatcatgagcgcatgtcttatctcctataccaaatgttatgtggaatcaagcacctt
cactctgctgggatcatccacagggatttaaagcccagtaacatcgtggtgaagtctgat
tgcacattgaaaattttggactttggactggccaggactgcaggcacaagcttcatgatg
actccatatgtggtgacacgatattacagagcaccagaagtcatcttgggaatgggctac
aaagagaatgtggatatatggtctgtaggatgcattatgggagaaatggttcgtcacaaa
atcctctttccaggaagggattatattgatcaatggaacaaagtaattgagcaattagga
acaccatgtccagaattcatgaagaaattgcaacccacagtaagaaactacgtggagaat
cggcccaagtatgcaggtcttactttccctaagctctttccagattccctcttccctgct
gactccgagcacaataaacttaaagccagccaagccagggaccttttgtcaaagatgcta
gtcattgatccagccaaaaggatatcagtggatgatgccttacagcatccatacatcaac
gtctggtatgatcctgcagaagtggaggcgcctcctccacagatatatgataaacaactg
gatgaaagagaacataccattgaagaatggaaagaactgatctataaggaagtaatgaat
tctgaagaaaagactaaaaatggagtagtaaaaggacaaccttctccttcaggtgcagca
gtgaacagcagcgagagcctccctccatcctcttctgtcaacgacatctcctccatgtcc
actgaccagaccctggcatccgacactgacagtagcttggagacctcggcaggaccactt
ggttgttgcaggtga

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