KEGG   Antechinus flavipes (yellow-footed antechinus): 127551988
Entry
127551988         CDS       T08818                                 
Name
(RefSeq) cholesterol side-chain cleavage enzyme, mitochondrial
  KO
K00498  cholesterol monooxygenase (side-chain-cleaving) [EC:1.14.15.6]
Organism
afz  Antechinus flavipes (yellow-footed antechinus)
Pathway
afz00140  Steroid hormone biosynthesis
afz01100  Metabolic pathways
afz04913  Ovarian steroidogenesis
afz04925  Aldosterone synthesis and secretion
afz04927  Cortisol synthesis and secretion
afz04934  Cushing syndrome
Module
afz_M00107  Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
Brite
KEGG Orthology (KO) [BR:afz00001]
 09100 Metabolism
  09103 Lipid metabolism
   00140 Steroid hormone biosynthesis
    127551988
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    127551988
   04925 Aldosterone synthesis and secretion
    127551988
   04927 Cortisol synthesis and secretion
    127551988
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04934 Cushing syndrome
    127551988
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450 [BR:afz00199]
    127551988
Enzymes [BR:afz01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.6  cholesterol monooxygenase (side-chain-cleaving)
     127551988
Cytochrome P450 [BR:afz00199]
 Cytochrome P450, animal type
  CYP11 family
   127551988
SSDB
Motif
Pfam: p450 Cytomega_US3
Other DBs
NCBI-GeneID: 127551988
NCBI-ProteinID: XP_051838220
LinkDB
Position
2:641717517..641740243
AA seq 524 aa
MFTRGISQHSALAKCRHYLLGSPRQDGWTSNVRRVQLPARGSDPATFPLRDRRPRPFNEM
PLNGANGWMNLLHFWMENGMRNLHIRTLQGFQQLGPIYREKLGNTESVFIINPDDAACLF
KAEGPYPERYCVPPWVAYHTYMKKPIGVLFKSSESWKKDRVFLNQFVLALDSMNNFEPLL
TPISEDFVKKIYKEIERSDQGKYTVDLSQDLFRFAFESICNILFGERLGLLEEFVDPEAQ
KFIDAVSTMFDTSVPMLNLPPELFRMVRAKTWRDHVASWDLIFDRAESYVKTFYQDQKMR
SEVTKCYPGILYCLLDKNTMNFEDVKANVTEMMAGGVDTTSMTLQWCLYEMARNLKVQDM
LRNEVLAARRDAQGDVKLMLKSVPLLKAAIKETLRLHPIAITIQRYIPSDLVLQDYAIPA
KTLVQVAIFAMGKDPNFFPNPEKFDPSRWFQENTYFRALSFGFGPRQCLGRRIAELEMTI
FLMHILENFRIEVHKLSEVGTTFNLILMPDKPIVFTFRPFKPQL
NT seq 1575 nt   +upstreamnt  +downstreamnt
atgtttaccaggggaatttcacaacactcagctctggctaagtgccgtcattacctcctt
ggttcaccaagacaagatggttggacgtctaatgttcggagagttcagctgccagctaga
ggtagtgacccggccactttccctctccgggatcggagaccccggcccttcaatgagatg
cccttaaatggagccaatggttggatgaatctgctccatttctggatggagaatgggatg
cggaacctgcatatccgaaccttgcagggcttccaacagttaggaccaatttaccgggag
aaacttggcaatacggaatctgtttttatcatcaacccagatgatgctgcctgcctcttt
aaagcagaaggaccctatccagaaagatattgtgtcccaccatgggtggcttatcacacc
tacatgaaaaaacctattggagtccttttcaagagctctgaaagttggaagaaagatcgg
gttttcctgaaccagttcgtgttggctttggactccatgaacaattttgagccccttctc
accccaatttcagaggactttgtaaagaagatatacaaggagattgagaggagtgaccaa
ggaaagtacactgtggacctcagtcaggacctgtttcgatttgcttttgagtctatctgc
aacattctctttggggagcgtctggggctcctggaagagtttgtggaccctgaggcccag
aagttcattgatgccgtgtctacaatgtttgataccagtgttcccatgctgaacctccct
ccagaattgttccgcatggtcagggccaagacttggagggaccacgtggcctcgtgggac
ctgatttttgatcgagctgaaagttatgtgaagaccttctaccaggaccagaagatgaga
tcagaagtcactaagtgttacccgggcattctctactgtctcttagacaagaacaccatg
aattttgaagatgtcaaagccaatgttaccgagatgatggcaggaggagtagatacgaca
tccatgaccttgcagtggtgcctgtatgaaatggctaggaacctaaaggtacaagatatg
cttcggaatgaagtcctggctgcccggcgagatgcccagggagatgtgaagttgatgctt
aaatctgttccgcttctcaaagctgccatcaaggaaaccctgaggttacaccccattgca
atcaccatacaaaggtacattccttcggatttagttctccaggattacgccatccctgct
aaaacactggtccaggtggccatctttgccatggggaaggatcctaacttcttccccaac
ccagaaaagtttgatccctccagatggtttcaagagaatacctacttccgggctctgagc
tttggttttggccctcggcagtgcctcggacggaggattgctgagttggagatgaccatc
tttctgatgcatattctggagaatttcaggatcgaagtccacaagctttcagaagtgggg
accacctttaatctcatcttgatgcctgacaagcccatcgtgttcacctttcggcccttc
aagccccagctgtaa

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