KEGG   Addendum: AAD32742
Entry
AAD32742          CDS       T10000                                 
Symbol
mmcR
Name
(KEGG) mitomycin 6-O-methyltransferase (EC:2.1.1.316)
  KO
K21427  mitomycin 6-O-methyltransferase [EC:2.1.1.316]
Taxonomy
TAX:1914
  Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces lavendulae
SSDB
Motif
Pfam: Methyltransf_2 Dimerisation Methyltransf_12 Methyltransf_11 Methyltransf_25 Methyltransf_23 HTH_20 Methyltransf_31 SelB_WH_2nd_bact
Other DBs
NCBI-ProteinID: AAD32742
GB: AF127374
UniProt: Q9X5T6
Structure
LinkDB
AA seq 349 aa
MTVEQTPENPGTAARAAAEETVNDILQGAWKARAIHVAVELGVPELLQEGPRTATALAEA
TGAHEQTLRRLLRLLATVGVFDDLGHDDLFAQNALSAVLLPDPASPVATDARFQAAPWHW
RAWEQLTHSVRTGEASFDVANGTSFWQLTHEDPKARELFNRAMGSVSLTEAGQVAAAYDF
SGAATAVDIGGGRGSLMAAVLDAFPGLRGTLLERPPVAEEARELLTGRGLADRCEILPGD
FFETIPDGADVYLIKHVLHDWDDDDVVRILRRIATAMKPDSRLLVIDNLIDERPAASTLF
VDLLLLVLVGGAERSESEFAALLEKSGLRVERSLPCGAGPVRIVEIRRA
Reference
PMID:10099135
  Authors
Mao Y, Varoglu M, Sherman DH
  Title
Molecular characterization and analysis of the biosynthetic gene cluster for the antitumor antibiotic mitomycin C from Streptomyces lavendulae NRRL 2564.
  Journal
Chem Biol 6:251-63 (1999)
DOI:10.1016/S1074-5521(99)80040-4
Reference
PMID:17461583
  Authors
Gruschow S, Chang LC, Mao Y, Sherman DH
  Title
Hydroxyquinone O-methylation in mitomycin biosynthesis.
  Journal
J Am Chem Soc 129:6470-6 (2007)
DOI:10.1021/ja0700193
Reference
PMID:21538548
  Authors
Singh S, Chang A, Goff RD, Bingman CA, Gruschow S, Sherman DH, Phillips GN Jr, Thorson JS
  Title
Structural characterization of the mitomycin 7-O-methyltransferase.
  Journal
Proteins 79:2181-8 (2011)
DOI:10.1002/prot.23040

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