KEGG   Addendum: AAF67508
Entry
AAF67508          CDS       T10000                                 
Symbol
novO
Name
(KEGG) 8-demethylnovobiocic acid C8-methyltransferase (EC:2.1.1.284)
  KO
K12705  8-demethylnovobiocic acid C8-methyltransferase [EC:2.1.1.284]
Taxonomy
TAX:193462
  Lineage
Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces niveus
SSDB
Motif
Pfam: Methyltransf_25 Methyltransf_31 Methyltransf_11 Methyltransf_23 Methyltransf_12 Ubie_methyltran CMAS MTS Methyltransf_4 Methyltransf_32 PrmA FtsJ Methyltransf_2 UPF0020 PCMT MetW AviRa
Other DBs
NCBI-ProteinID: AAF67508
GB: AF170880
UniProt: Q9L9F3
Structure
LinkDB
AA seq 230 aa
MKIEAITGSEAEAFHRMGSQASHRYDEFVDLLVGAGIADGQTVVDLCCGSGELEVILSSR
FPSLNLVGVDLSEDMVRIAREYAAEQGKALEFRHGDAQLLAGMEDLAGKADLVVSRNAFH
RLTRLPAAFDTMLRLAKPGGAVLNCSFIHPSDFDESGFRAWVTFLNQRPWDSEMQIVWAL
AHHYAPRLDDYREALAQAARETPVSEQRVWIDDQGYGVPTVKCFARRAAA
Reference
  Authors
Steffensky M, Muhlenweg A, Wang ZX, Li SM, Heide L
  Title
Identification of the novobiocin biosynthetic gene cluster of Streptomyces spheroides NCIB 11891.
  Journal
Antimicrob Agents Chemother 44:1214-22 (2000)
DOI:10.1128/AAC.44.5.1214-1222.2000
Reference
  Authors
Pacholec M, Tao J, Walsh CT
  Title
CouO and NovO: C-methyltransferases for tailoring the aminocoumarin scaffold in coumermycin and novobiocin antibiotic biosynthesis.
  Journal
Biochemistry 44:14969-76 (2005)
DOI:10.1021/bi051599o

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