KEGG   Addendum: AAF86392
Entry
AAF86392          CDS       T10000                                 
Symbol
fkbC
Name
(KEGG) polyketide synthase FkbC
  KO
K16376  polyketide synthase FkbC
Taxonomy
TAX:1912
  Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces violaceusniger group
Organism
Streptomyces hygroscopicus
SSDB
Motif
Pfam: ketoacyl-synt Acyl_transf_1 KR Ketoacyl-synt_C PKS_DH_N PS-DH PP-binding KAsynt_C_assoc ADH_zinc_N_2 Thiolase_N ADH_N adh_short ADH_zinc_N Epimerase DUF7080 CurL-like_PKS_C Docking ACP_syn_III Erythro-docking
Other DBs
NCBI-ProteinID: AAF86392
GB: AF235504
UniProt: Q9KIE1
LinkDB
AA seq 3591 aa
MAENDLIEALRTSVKDNAQLRRENTALRAAANEPLAVVGMACRLPGGVTSPEELWQLVAD
GRDAIGDFPTDRGWDVAALHAAAESATGRAGALAGAADFDAAFFGISPREATALDPQQRI
LLEIAWEALEHAGIVPDTLRGSDTGVFVGGFYYGYGTGADLGGFGAYSTQPAVLAGRLSY
FFGMEGPAVTVDTACSSSLVALHQAGQALRTGECSLALVGGVTVMASPQTFVEFSRQGGV
APDGRCKAFADAADGTGFAEGAGVLVVEKLSDAERNGHTVLAVVRSSAVNQDGASNGISA
PNGPSQQRVIRQALHKAGLAPADVDVVEAHGTGTTLGDPIEAHAILATYGQEREVPLLLG
SLKSNIGHAQAAAGVAGVIKMVMAMRYGIAPKTLHVDEPSSHVDWTEGAVELLTEARAWP
DAGRPRRAGVSAFGVSGTNAHVILEGVPGPSRGESAVDGLVPLPVSARSEVSLRGQVERL
EGYLRGGGVDVAAVAQGLVRERAVFGHRAVLLGDARVMGVAVDQPRTVFVFPGQGAQWVG
MGVELMACSAVFAARMEECARALLPHTGWDVREMLARPDVAERVEVVQPASWAVAVSLAA
LWQAHGVVPDAVVGHSQGEIAAACVAGALSLEDAARVVALRSQVIAGRLAGRGAMASVAL
PAGEVDLVEGVWIAARNGPSSTVVAGDPSAVEEVVTRYEAEGVRVRRIAVDYASHTPHVE
AIEDELAEVLEGISGGTGSVAWWSTVDSAWVTEPVDEGYWYRNLRRPVALDAAVAELDGS
VFVECSAHPVLLPAMEQAHTVASLRTGDGGWERWLTALAQAWTLGTAVDWDTVVEPVPGR
LLDLPTYAFEHRRYWLEAAGATDLSAAGLTGAAHPMLAAVTALPADDGGGVVLTGRISLR
THPWLADHAVRGTVLLPGTAFVELVIRAGDETGCGVVDELVIETPLVVPVTGAVDVSVTV
EGADEAGRRRVTVHARTEGTDSWTRHASGTLGRAGSVAAVPPPAWPPPGARRVDVSAFYE
RLAETGYSYGPAFQGLRTAWRDGETLYAEVEIAGEQADDTPHYGVHPALFDAALHVTCLP
LLAEQEAEVRLPFSWSGVRFHTTGATTLRVTITQGPDGAAVHATDPVGQPVVTVAALTAR
PVNVDGDAAVVRNSLYGLSWTELPTPGPGPADAVHIVSALPEPGADVLDETYRLTEFVLG
ELHRVIAEDGPAETTLVVRIDAGPVGGAVAGLVRSAQAEHPGRFVLVETGTDTPIEALAA
ATTLAEPYVRVTDGRYEAPRFTRTAAAETPEPLLDPDGTVVITGGSGVLAGLLARHLVAE
HGARHLLLLSRSEPPADTPGVHIRCDVADRDQLAAALAAAGRPLTAVFHTAAVLDDGVTT
ALTPERLATTLRPKADGAWHLHELTRDADLRSFVLYSSVAGIMGGRGQGNYSAANGFLDG
LATLRHAEGLPALSLAWGLWADDSGLTGSMSGTNRTRVRRGGFRPMSAGVGMRLLEAAAG
TGTAFAVAATMDLTAHTSPLFADLRRAVSRPAAATAVPLADRLGTMSGAERDTALLALVR
DNAAAVLGHADAADVSADAAFKELGIDSLTAVELRNRLAAATGVRLPATLVFDYPTPRAI
ASRLDEALVGGAAPVAVPTAAATRDEPLAIVGMACRLPGGVTSPDDLWRMVDSGGDAVTG
FPADRGWDPSGLTGGSDTDRGGFLSDAAGFDAAFFGISPREARAMDPQQRILLETTWEAF
ESAGIVPGTLRGSDTGVFMGAFSYGYGVGADLDGFGSIGMQPSVLTGRISYFYGLQGPAF
TVDTACSSSLVALHQAGHALRHGECSLALVGGVTVMATPTGFVEFQQQGGLSPDGRCRAF
ADAANGTGWAEGAGVLVLERLSDAERNGHTVLAVVRGSAVNQDGASNGLSAPNGPSQQRV
IQQALVNAGLRAADVDVVEAHGTGTTLGDPIEAQAILATYGQEREVPLLLGSLKSNIGHA
QAAAGVAGVIKMVMAMRYGIAPKTLHVDEPSSHVDWSAGAVELLTEARPWPESDRAPHAG
VSSFGVSGTNAHVILEGVPGPSRGESVVDGLVPLPVSARGEVSLRGQVERLEGYLRGGGV
DVAAVAQGLVRERAVFGHRAVLLGDARVTGVAVDQPRTVFVFPGQGAQWVGMGVELMAHS
AVFAARMEECAQALLPHTGWDVREMLARPDVAERVEVVQPASWAVAVSLAALWQAHGVVP
DAVIGHSQGEIAAACVAGALSLEDAARVVALRSQVIAARLAGRGAMASVALPAGEVGLVE
GVWIAARNGPASTVVAGDPSAVEEVVARYEAEGVRVRRIAVDYASHTPHVEAIEDELAKV
LEGVAGKAASVAWWSTVDSAWVTEPVDEGYWYRNLRRPVALDAAVAELDGSVFVECSAHP
VLLPAMEQAHTVASLRTGDGGWERWLTALAQAWTLGTAVDWDTVVEPVPGRLLDLPTYAF
EHRRYWLEAAGATDLSAAGLTGAAHPMLAAVTALPADDGGVVLTGRISLRTHPWLADHAV
RGTVLLPGTAFVELVIRAGDETGCGIVDELVIESPLVVPVTAAVDVSVTVEGADEAGRRP
VTVHARTEGTGSWTRHASGTLTPDTPDTPGVVGVEPFSQWPPVTAVAVDVSGFYDELRDA
GYEYGSAFQGLRAAWRDGDTVYAEVALPDEQAAEADGFGVHPALLDAALHAVALTTPDDS
AAGLPFAWKGARFVATGSAMLRAVITRDGDELSLRVADSAGQLVAEIRTVRTRPLSPPVG
TGLMRLTWIEVAAPTDVPATDVDVITLPAADGDDPVAETRALTTRLLTALTGSGGDLLVH
TTAGLATGAAAGLLRAAQAEQPGRFVHVETESGVTLAPEQQRIAVALGEPRLRLRGGRFE
AARLTRVPEPLTVPDSDTWLIRPARTGTLDGLTAADSAEPRRPLAPAEVRIGVRAAGLNF
RDVLIALGTYPGQGVLGGEAAGIVLETGADVSGLAPGDRVFGLVGTGFGPTVIADHRMLG
RMPDGWTFPQAASVMTAFATAWYGLVDLAGLRPGEKVLIHAATGGVGSAARQIARHLGAE
VYATTSAAKRHLVDLDGAHLADSRSTAFADAFPPVDVVLNSLTGELLDASVGLLAPGGRF
IEMGKTDIRHAVQRPFDLMDAGPDRLKEIIAELLGLFARGVLHPLPVTVHDMRQVREALA
TMSRGEHTGKIVLTVPRPLDPEGAVVITGGSGTLAGILARHLNHPHTYLLSRTPPPDTTP
GTHLPCDVGDPHQLATTLAHIPQPLTAVFHTAGTLDDALLDNLTPDRIDTVLKPKADAAW
HLHRLTRDTDLAAFVVYSSAAGVLGTPGQGNYAAANAFLDALAEHRRAQGLPGLSIAWGL
WDQASGLTADLTDADRRRMRKGGASALTAEQGMRMYDAAVHTGTGSVVAVAGDLPPDLPL
LRGRPKPSARRSARNEQERPTDLLALVRQKAAAVLGHADPEDIPEDAAFRELGVDSLIAV
QLRNGLNEATGLRLSATLVFDYPSPRALADRIGELLSPDDPVTVVLAQLDRLEALVAGVD
PGARQADAIGTRLDALLNRWRRETRPTTPAGVLSADATADEIFDLIDRELR
Reference
PMID:10863099
  Authors
Wu K, Chung L, Revill WP, Katz L, Reeves CD
  Title
The FK520 gene cluster of Streptomyces hygroscopicus var. ascomyceticus (ATCC 14891) contains genes for biosynthesis of unusual polyketide extender units.
  Journal
Gene 251:81-90 (2000)
DOI:10.1016/S0378-1119(00)00171-2

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