Bacteria; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces

Weitnauer G, Muhlenweg A, Trefzer A, Hoffmeister D, Sussmuth RD, Jung G, Welzel K, Vente A, Girreser U, Bechthold A

Biosynthesis of the orthosomycin antibiotic avilamycin A: deductions from the molecular analysis of the avi biosynthetic gene cluster of Streptomyces viridochromogenes Tu57 and production of new antibiotics.

Chem Biol 8:569-81 (2001)
DOI:10.1016/S1074-5521(01)00040-0

Weitnauer G, Hauser G, Hofmann C, Linder U, Boll R, Pelz K, Glaser SJ, Bechthold A

Novel avilamycin derivatives with improved polarity generated by targeted gene disruption.

Chem Biol 11:1403-11 (2004)
DOI:10.1016/j.chembiol.2004.08.016

Weitnauer G, Gaisser S, Trefzer A, Stockert S, Westrich L, Quiros LM, Mendez C, Salas JA, Bechthold A

An ATP-binding cassette transporter and two rRNA methyltransferases are involved in resistance to avilamycin in the producer organism Streptomyces viridochromogenes Tu57.

Antimicrob Agents Chemother 45:690-5 (2001)
DOI:10.1128/AAC.45.3.690-695.2001