| Entry |
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| Symbol |
nocA
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| Name |
(KEGG) nocardicin nonribosomal peptide synthetase NocA
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| KO |
| K19102 | nocardicin nonribosomal peptide synthetase NocA |
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| Taxonomy |
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| Lineage |
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Mycobacteriales; Nocardiaceae; Nocardia |
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| Organism |
Nocardia uniformis
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| AA seq |
3692 aa
MRDSEEWERGARVDHGPGGLWRSIAAVLAGGGARAAVVRGARSLSFAELDARTSALAGRL
RAAGVGAERPVAVLAEDGVDQVVACLAVFRAGGVYLPVDPAWPAGRRAAVLADAGPAAVV
VGGALDGGVAGAGALHAGAPGAGSTDAVLAAEAPVLPVHVGDDEGAEGVPWPEPERDQAA
YLVYTSGSTGRPKGVLVTHGALANRMLWWQGEHPLGPDDVLMATASPAFDIAVWELLAAF
VGGARLVIAEHRLRGVVPHLPELMTDHRVTVAHFVPSVLEELLGWMADGGRVGLRLVVCG
GEAVPPSQRDRLLALSGARMVHAYGPTETTITVVHDECRADDPAPGLPLGRPMHNAAVAV
VDADGRRAPVGVAGELVVGGVPLARGYLGRPGETAARFVPDWLGLGPAGGRVYRTGDRAR
RLPDGRIEFLGRVDDEFKVRGHRVDPAEIESLLHQHPLVGRAAVRLADGAHVVAYLQGSA
DPAELRAHLADRLPLAVIPTRWVRLDRFPLTPNGKVDYAALPAAPARANGQDGQGGQGNQ
HGPDGPDGPDGPDGRGDQVSRHDPDDPNHPNGQGSQNGSHGQSGLPGPHGRATTALEREL
AELWARDLGLDAVGVSDDFLALGGHSLLATRTAAAAWRRRRVRLSPADVLSARTVAALAR
RIEELAVSAPEPAAAPEPAAATADEAPAELPLTSAQERILFEEEFLGGPGLFTVPVPTRW
RGPVRVPELRTALDALVRRHPVLRAALADDGGPVRLVLHEAAPVPLVVEDLRALAPAARE
ARVVAAGEEAAAEPFDLHRPPLLRARLLRLADEEHVFLPVLHHLVCDRWSMRLLAEDLRE
LYASALDGRAPRLGPAASPVAVPRAGSGHDLDHWLRRLDGAALDGDLAVGPRHRADHGHR
AGRVLRLLPAERTAALNALCAARGVTPFVVLLAAFQVLLHRFSDSDDVVVAVPVDGRDAP
GAYDVVTMLVNTVPLRADLRGDPRFSDVLDRARDEAREAVAHQAAPMGRLAGALGLRRGA
GHHSLMRHMLVWEDSLGVPVELPGVVAEPMRPPSHTTAFDLTLIARAVPDGVDLELEFNH
DVLDAASAALVADGFTALVDHVLADPDVRIGRTRLTGAPVEPVLAGPVAPPAPPVLRLVR
DAAARRPDAPAVVDGEVVTGYAELVRRADAVAARIRAAGGGPGDVVGVCLPRSTDLVAAL
LGVLAAGRAFLPLSPEDPDDRITRQLDLGGARLVIAADADRFAADRFAGVTAVSPLVPAE
GAGEAPLAPLPEPLPGDAAYVIFTSGSTGEPKGVVVEHRALADHVRWAVGEYGLTAGDRA
LQFCAVAFDVLVEEVLPTLASGAAVVLRDEESATSAQALVELCAARGVTVANLPTGYWER
LVAAFDEDGTALPPSVRLVVIGGQQVDRSAVERWHRLPNPVRLVNAYGPTEMTIGATAAD
LVPGGGVPIGGPTENTRAYLLDRYLAPVPDGVVAELYLAGSGLARGYSRRPGLTGERFLP
DPFAGGGQRMYRTGDLAVRRDGALHFIGRVDRQVKVRGHRIELDEVESALTAAPGVAEAA
VLLRGGRLVAHVAAPPEVDGAGLRAHLAGRLPAFMVPSVVVVSRALPRTSTGKVDRNALT
AEPDEPADLALPGDDEPGDERERATSALWAQVLGVARVGVRDSFFDLGGHSLLAMDLVRR
MHGQGYRRLRVPDLFEHPTIEALAPWADDAPTATGTGATEPGATEPGATGPGVAGPGVAA
PGAAPGVVAPNATVPGVAAPGAVPDATAPDATAPGAVVPGAVPSSAVPSSPVPPPVPDSA
PLSWAQLGIWAHAAVSGSRTFHLPVVLRLSGPLSESDLAGATAALTARHDLLRSALADGP
EGPEWRPARNAPVPLGVLDAPAPDLAERIAELVAEPFDLRAAPPVRWTLLRLGPDDAALV
VVLHHIAGDGWSAGLLVRELAELYAARTGRRPAALPPAPSFLALAAADRSAPPDRDGLAF
WTEALRGAPDRMDLPADRLPAEPRDPGRHRARVPLPPATASALAELARRERATPFMVLLA
GVQAWLARCCRQSDVVVGAPVADRDDDVAAGVLGPLVNVLPVRVRVDPARSFAGQVARTR
AAALAVFEHRSTPTQQIVRHLGLSGRGLSHVVFDLDEAAGPETTAFGGVTARTVPQTPAL
GAFDLEVTARQGRDGLSVELRAAADLFGQAGVEHLAAALARLLTGVAERPDAPLRSIDLL
GDDERRRLLVGLNARHRPERPEGVLALVADWVARTPDATAVTAPTGRLTYRELDALSDGV
AGWLRDRGLPAEGLVATRLGRCLELPAVVLGIWKAGGAYVPLDPAQPAERHRRILADCRP
RAVVADRDDPVFGDTPLLTVADLRPGAPAPVRPPEPDRLAYVAYTSGSTGEPKGVQCAHH
GLANQLMWSRRAYPLNPGEALAQVAAVGFDISLWELLHPLTSGGRLVVLDQERHGDVVAI
AELVAAERVVVLHLVPTLLEHYLDEGPADSLRHVVCGGERLSPGLPARFAARTPAALNHT
YGPTEASIIVTHWRSPDPAPDAVSLGAPLPGARVYLLDPHGQPVPVGVVGELVLGGEVLA
RGYLGRPGATAERFLPDPFSDVPGARAYRTGDLARHRPDGGLEFVGRADRQVKILGVRVE
PHEVETALVANPAVAACAVLPREDARGAVGLVGYLVPADRDADPGQLRAEVGRALRERLP
RAMVPSRLVVLEALPVGPTGKLDVGALPEPDEAPAPLPAPSPTGPGTAAERDLAAIWAQV
LPVPGDRVIGPQDNFFELGGDSVSAIRVVARARAAGLRVELGRVLRAGSLAELAASASPV
EAPVAVRPAPPDARLWLTPAQRRFLATAVPGHFNQAVLTEPAERVDPEALRAALQAVAAH
HDAFRLRPVRADGRRQDHAVLAPRTDDLVVVLTAGAPFHDDSADELAAPAHRAVDVDRGP
LLAALLAERPDGGQVVLLTAHHLAIDTASWETVLSDLDIAYRQVARGEQVVLPTPITPFA
DLARALPAFTARLDTPAQRAHWHDQLADLPPLPGATGGGTGVGSVLLALGEPATRALTAA
ASRHRLRVDELLLAALVRVIARWTGSPRVGLLREAHGRSGPPDWPDLTGTVGWLTAVYPV
RVDLPADEPLAALHAVREALGAVPDGGVGYGLLHPDPEAEPDLVVNYLGATTGGPGSGLF
VRAARQAIGGYAAGQAAVRGVEVIAGIDERGLWVEWLHDRERFPESTVDSLAEGLRVALA
ELVPPLEGPFGVAAVPTDFPAARVPGDRLRAVLAARSDVRDVLPLSPAQQGMLAWHLARP
GSVAYHTQILFAADGDVDEARLRAAWQRVVDRTDVFRTAFVHTGLEEPVQVVGASPPVDW
RGHAGAGPDEVLAADRDEPFDLSAPGQQRWHWIDGGAAGRWLLWSHHHILLDGWSLPLVL
ADVAAAYTAGPAWAPPRRPGYGAYLSWLSTRDEEAGAAFWRGRLAGATPTRLGRAGTPGA
ASLVTADLPEAATRALTGLAERSRATLHSVVLAAWSLVLGLRCASDDVVFGVVMSLRPDE
IPDSEHLVGLCLNTVPLRVRVDADGELPELFRRIQQDLVEGYQHAAHPLGRVRGWAGAPD
ALFDSIVVFENYPGDRTGQALGADGALRVVRAVESTEFAVSLTVLPDERLTFELTHLSHA
LTSAEAGELVRRLARLLERIAESGGPEGRRNP |
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| Reference |
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| Authors |
Gunsior M, Breazeale SD, Lind AJ, Ravel J, Janc JW, Townsend CA |
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| Title |
The biosynthetic gene cluster for a monocyclic beta-lactam antibiotic, nocardicin A. |
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| Journal |
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