KEGG   Addendum: ABI22137
Entry
ABI22137          CDS       T10000                                 
Symbol
sfmM2
Name
(KEGG) L-tyrosine C3-methyltransferase (EC:2.1.1.304)
  KO
K21460  L-tyrosine C(3)-methyltransferase [EC:2.1.1.304]
Taxonomy
TAX:1914
  Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces lavendulae
SSDB
Motif
Pfam: Methyltransf_2 Dimerisation Methyltransf_25 Methyltransf_12 MTS Dimerisation2-like_dom Methyltransf_31 Methyltransf_11 DUF7639 Methyltransf_23
Other DBs
NCBI-ProteinID: ABI22137
GB: DQ838002
UniProt: B0CN31
LinkDB
AA seq 366 aa
MTISLENTTVGQNPAGGPPTGKAPLDMEGLAWILFGASAFQYLNAACELNLFELLENKPG
LTKPQIGAELGLADRANDILLLGATATGMLTVEDGRYQLATVLAELLKTDDWQRFKDTVG
FEQYVCYEGQIDFTESLRSNSNVGLRRVRGSGRDLYHRLHENPQMEQAFYKYMRSWSELA
NQHLVEVLDLSGTSKLLDCGGGDAVNSIALAQANPHIEAGILEIPPTAPLTEKKIAEAGL
SDRITVKPGDMHTDEFPTGYDTVMFAHQLVIWTPEENTALLRKAYNALPEGGRVIIFNSM
SNDEGDGPVVAALDSVYFAALPAEGGMIYSWATYEESLTKAGFNPETFQRIDFPGWTPHG
VIIATK
Reference
  Authors
Li L, Deng W, Song J, Ding W, Zhao QF, Peng C, Song WW, Tang GL, Liu W
  Title
Characterization of the saframycin A gene cluster from Streptomyces lavendulae NRRL 11002 revealing a nonribosomal peptide synthetase system for assembling the unusual tetrapeptidyl skeleton in an iterative manner.
  Journal
J Bacteriol 190:251-63 (2008)
DOI:10.1128/JB.00826-07
Reference
  Authors
Tang MC, Fu CY, Tang GL
  Title
Characterization of SfmD as a Heme peroxidase that catalyzes the regioselective hydroxylation of 3-methyltyrosine to 3-hydroxy-5-methyltyrosine in saframycin A biosynthesis.
  Journal
J Biol Chem 287:5112-21 (2012)
DOI:10.1074/jbc.M111.306316

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