KEGG   Addendum: ADI58628
Entry
ADI58628          CDS       T10000                                 
Symbol
asuE1
Name
(KEGG) protoasukamycin 4-monooxygenase (EC:1.14.13.215)
  KO
K27593  protoasukamycin 4-monooxygenase [EC:1.14.13.215]
Taxonomy
TAX:40318
  Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces nodosus
SSDB
Motif
Pfam: FAD_binding_3 FAD_oxidored FAD_binding_2 Pyr_redox_2 NAD_binding_8 GIDA Pyr_redox_3 HI0933_like DAO
Other DBs
NCBI-ProteinID: ADI58628
GB: GQ926890
UniProt: D7P5V0
LinkDB
AA seq 407 aa
MTTSDPDLSGLETDVCVVGGGATALYGALLCARAGQSVVLVFSQPEFEAAGAGISPLLAP
PTLGLLAASGIDEQLTAAGRKVLGVDDHGSTGMLSSWRYADHAGIARPYGLTVPTGTTVQ
ALLAELRAQPRATVLTGEGVVSVEQDDERVVLGFERAAGQDGGVPARRRVAARYAVAADG
RQSALRDLVGIRLEVSAFDRPAWLLVAPDVPGRESVLLVRHRAPRALFTIPTPGPSSAVV
WAPDRDQEKQLEQGGPAELAEQIKEVDPELSEWLGTVGGRTSPVMRLGFSLWRAPSWRVG
RVLLVGESVHGLHTLGGQGLNQSLQGAASAARAIGEALASGDPAAIEDYERVRRPHVERL
QDLQWNLQALGYGTAPAVKGAHEDFIDVMTALPPELVAQLDGSDTRA
Reference
PMID:20522559
  Authors
Rui Z, Petrickova K, Skanta F, Pospisil S, Yang Y, Chen CY, Tsai SF, Floss HG, Petricek M, Yu TW
  Title
Biochemical and genetic insights into asukamycin biosynthesis.
  Journal
J Biol Chem 285:24915-24 (2010)
DOI:10.1074/jbc.M110.128850
Reference
PMID:23890006
  Authors
Rui Z, Sandy M, Jung B, Zhang W
  Title
Tandem enzymatic oxygenations in biosynthesis of epoxyquinone pharmacophore of manumycin-type metabolites.
  Journal
Chem Biol 20:879-87 (2013)
DOI:10.1016/j.chembiol.2013.05.006

KEGG   Addendum: ADI58638
Entry
ADI58638          CDS       T10000                                 
Symbol
asuE2
Name
(KEGG) NADH-dependent FMN reductase
  KO
K27594  NADH-dependent FMN reductase [EC:1.5.1.-]
Taxonomy
TAX:40318
  Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces nodosus
SSDB
Motif
Pfam: Flavin_Reduct DUF389
Other DBs
NCBI-ProteinID: ADI58638
GB: GQ926890
UniProt: D7P5W0
LinkDB
AA seq 185 aa
MSTHTARRAGATAGHDRDRGTEPGRTEFRRAMGLLPTGVAVVTVGSGEQTEAVTVGSVVS
VSLDPALVLVSLGSTGRLVEAIDRAGGFAVNVLTTEQSDLSACFASHDRPHGRGAEERLG
GVAGASGHVLLRDAVLSMECRTEHRYPGGDHVLFLGRVDELHTAEAAGSPLVHHRGAYTT
LKDPC
Reference
PMID:20522559
  Authors
Rui Z, Petrickova K, Skanta F, Pospisil S, Yang Y, Chen CY, Tsai SF, Floss HG, Petricek M, Yu TW
  Title
Biochemical and genetic insights into asukamycin biosynthesis.
  Journal
J Biol Chem 285:24915-24 (2010)
DOI:10.1074/jbc.M110.128850
Reference
PMID:23890006
  Authors
Rui Z, Sandy M, Jung B, Zhang W
  Title
Tandem enzymatic oxygenations in biosynthesis of epoxyquinone pharmacophore of manumycin-type metabolites.
  Journal
Chem Biol 20:879-87 (2013)
DOI:10.1016/j.chembiol.2013.05.006

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