KEGG   Addendum: ADO85591
Entry
ADO85591          CDS       T10000                                 
Symbol
penE
Name
(KEGG) pentalenolactone D synthase (EC:1.14.13.170)
  KO
K18091  pentalenolactone D synthase [EC:1.14.13.170 1.14.13.171]
Taxonomy
TAX:1905
  Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces exfoliatus
SSDB
Motif
Pfam: FMO-like NAD_binding_8 Pyr_redox_2 Pyr_redox_3 DAO NAD_binding_9 Shikimate_DH FAD_binding_2 2-Hacid_dh_C
Other DBs
NCBI-ProteinID: ADO85591
GB: HQ292066
UniProt: E3VWK3
LinkDB
AA seq 584 aa
MREKYRQERDKRSVGRTYQFARGDFSRYARDPYTERQEREPLTDEVDVAVVGAGIGGLLT
GAHLRKETGLERIRLIDGAGDVGGTWYWNRFPGVRCDVESYIYMPLLEETGTIPREKYST
GPEIFAHLQQIAHRYDLYRDALFQTTVTELRWDEAAGRWLVSTDRGDLIRARYVAMSIGL
MHRPKLPGLPGLETFAGHSFHTSRWDFDYTGGDSTGGLTKLKDKKVGVIGTGSTTIQLAP
HLAEWAEQLILFQRTPAAVDVRGNRPTPPEWAAGLAPGWQQRRMENFHALTSGVPQDEDL
VQDRWTQTTAKLAAAILPTGDTGGDPKERALAAERADFLKMEELRARIDSVVTDPATAAA
LKPYYRVYCKRPCFHDGYLQTFNRPNVTLVDTQGQGVERLTPAGVVANGREYPLDCLIFA
TGYEHEFAVPYTERAGYDIVGRDGLRLSEKWADGARTLHGLQVNGFPNCFILSKVQAGRH
VNIAYMLGEQTRHLAHIVKCVEERGHQVVEASEAGEKEWVEEILRLATNDIDFLENCTPG
LYNNEGDPSGLPLLNSSYGGGSVEFVNILRRWREAGDLAGLELR
Reference
PMID:21284395
  Authors
Zhu D, Seo MJ, Ikeda H, Cane DE
  Title
Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone.
  Journal
J Am Chem Soc 133:2128-31 (2011)
DOI:10.1021/ja111279h
Reference
PMID:21250661
  Authors
Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE
  Title
Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.
  Journal
Biochemistry 50:1739-54 (2011)
DOI:10.1021/bi1019786

KEGG   Addendum: ADO85575
Entry
ADO85575          CDS       T10000                                 
Symbol
pntE
Name
(KEGG) pentalenolactone D synthase (EC:1.14.13.170)
  KO
K18091  pentalenolactone D synthase [EC:1.14.13.170 1.14.13.171]
Taxonomy
TAX:29301
  Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces
Organism
Streptomyces arenae
SSDB
Motif
Pfam: FMO-like NAD_binding_8 Pyr_redox_2 Pyr_redox_3 DAO NAD_binding_9 FAD_binding_2 Shikimate_DH
Other DBs
NCBI-ProteinID: ADO85575
GB: HQ292065
UniProt: E3VWI7
LinkDB
AA seq 589 aa
MDLEAVREKYRQERDKRGVGRTYQFARGDFSRYARDPYTERREREPLTDEVDVAVVGAGI
GGLLTGARLREETGLERIRLIDEAGDVGGTWYWNRFPGVRCDVESYVYMPLLEEIGTIPT
EKYSTGPEIFAHLQRIAHRYGLYRDALFQTTVTELRWDEAAARWLVSTDRGDLFRARYVA
MSIGLMHRPKLPGLPGLETFAGHSFHTSRWDFGYTGGDSTGGLTGLKDKRVGVIGTGSTT
VQLAPHLAEWAERLYIFQRTPAAVDVRGNRPTPPGWADGLDAGWQQRRMENFHALTSGIP
QDEDLVQDRWTQTTAELATAILPTGDTGGDPKERALAAERADFRKMEELRARIDSVVTDP
ATAAALKPYYRVYCKRPCFHDGYLQTFNRPNVTLVDTQGQGVERLTASGVVANGREYPVD
CLIFATGYEHEFAVPYTERAGYDIVGRGGVRLSEKWAQGAHTLHGLQVHGFPNCFILSKV
QAGRHVNIAYMLGEQTRHLAHIVKCVEERGHRVVEASEAGEKEWVEEILRLASGDLDFLE
NCTPGLYNNEGDPGGLPLLNSSYGGGSVEFVNILRRWREAGDLAGLELR
Reference
PMID:21284395
  Authors
Zhu D, Seo MJ, Ikeda H, Cane DE
  Title
Genome mining in streptomyces. Discovery of an unprecedented P450-catalyzed oxidative rearrangement that is the final step in the biosynthesis of pentalenolactone.
  Journal
J Am Chem Soc 133:2128-31 (2011)
DOI:10.1021/ja111279h
Reference
PMID:21250661
  Authors
Seo MJ, Zhu D, Endo S, Ikeda H, Cane DE
  Title
Genome mining in Streptomyces. Elucidation of the role of Baeyer-Villiger monooxygenases and non-heme iron-dependent dehydrogenase/oxygenases in the final steps of the biosynthesis of pentalenolactone and neopentalenolactone.
  Journal
Biochemistry 50:1739-54 (2011)
DOI:10.1021/bi1019786

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