KEGG   Addendum: AHH02781
Entry
AHH02781          CDS       T10000                                 
Symbol
NNMT
Name
(KEGG) norajmaline N-methyltransferase (EC:2.1.1.392)
  KO
K27779  norajmaline N-methyltransferase [EC:2.1.1.392]
Taxonomy
TAX:4060
  Lineage
Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; asterids; lamiids; Gentianales; Apocynaceae; Rauvolfioideae; Vinceae; Rauvolfiinae; Rauvolfia
Organism
Rauvolfia serpentina
SSDB
Motif
Pfam: Methyltransf_11 Methyltransf_31 Methyltransf_25 Methyltransf_23 CMAS Ubie_methyltran Methyltransf_12 MetW Methyltransf_15 MTS Methyltransf_29 Succ_CoA_lig CARME Methyltransf_32 UPF0020 DREV Methyltransf_20 Methyltransf_2
Other DBs
NCBI-ProteinID: AHH02781
GB: KC708449
UniProt: A0A075D6M1
LinkDB
AA seq 292 aa
MAEKQQAVTEFYNNTSPRGAWEFLLGDHLHEGFYDPGTTATISGSQAAAARMIDEALRFA
NIYDDPSKKPKNMLDIGCGVGGTCVHVAKQYGIQCKGITLSPEEVKCAQGIAKAQGLEEK
VSFDVGDALNLPYKDGTFDLVLTIECIEHVQDKEKFIREMIRVAAPGAPIVILSYAHRNL
SPSAESLKPDEKKVLKKICDNLALSCLCSSADFVRWLTQLPAEDIKTADWTQNTSPFFPL
LMKETFTWKGFTSLLMKGGWTAIKELLALRMMSKAADDGLLKFVAITCRKSK
Reference
  Authors
Levac D, Cazares P, Yu F, De Luca V
  Title
A Picrinine N-Methyltransferase Belongs to a New Family of gamma-Tocopherol-Like Methyltransferases Found in Medicinal Plants That Make Biologically Active  Monoterpenoid Indole Alkaloids.
  Journal
Plant Physiol 170:1935-44 (2016)
DOI:10.1104/pp.15.01813
Reference
  Authors
Cazares-Flores P, Levac D, De Luca V.
  Title
Rauvolfia serpentina N-methyltransferases involved in ajmaline and Nbeta -methylajmaline biosynthesis belong to a gene family derived from gamma-tocopherol C-methyltransferase.
  Journal
Plant J 87:335-42 (2016)
DOI:10.1111/tpj.13186
Reference
  Authors
Guo J, Gao D, Lian J, Qu Y
  Title
De novo biosynthesis of antiarrhythmic alkaloid ajmaline.
  Journal
Nat Commun 15:457 (2024)
DOI:10.1038/s41467-024-44797-z

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