KEGG   Addendum: APB62243
Entry
APB62243          CDS       T10000                                 
Symbol
famC1
Name
(KEGG) 12-epi-hapalindole U synthase / hapalindole U synthase subunit (EC:5.5.1.32 5.5.1.36)
  KO
K22971  hapalindole H/12-epi-hapalindole U/12-epi-fischerindole U/hapalindole U synthase [EC:5.5.1.31 5.5.1.32 5.5.1.33 5.5.1.36]
Taxonomy
TAX:56108
  Lineage
Bacteria; Bacillati; Cyanobacteriota; Cyanophyceae; Nostocales; Hapalosiphonaceae; Fischerella
Organism
Fischerella ambigua
SSDB
Motif
Pfam: HpiC1-like Ribophorin_II_3rd DUF4179
Other DBs
NCBI-ProteinID: APB62243
GB: KX451322
UniProt: A0A076N4W8
LinkDB
AA seq 227 aa
MKRKLIVAVVFLIFICLGINTPAHATSAVSIPINNAGFENPFMDVVDDYTIDTPPGWTTY
DPNNLVPEKRTTWTSNNGVGYVGPGTQFYNQLAPEGRNIGYIYLSQNPGSGVAGFEQILD
ATLEPDTKYTLTVDVGNLAGTFKGLSFAGFPGYRVELLAGDTVLAADHNNLFIKEGEFKT
STVTYTSTAKDLHLGQKLGIRLVNLLQDKFSGLDFDNVRLTTEPTET
Reference
PMID:26629885
  Authors
Li S, Lowell AN, Yu F, Raveh A, Newmister SA, Bair N, Schaub JM, Williams RM, Sherman DH
  Title
Hapalindole/Ambiguine Biogenesis Is Mediated by a Cope Rearrangement, C-C Bond-Forming Cascade.
  Journal
J Am Chem Soc 137:15366-9 (2015)
DOI:10.1021/jacs.5b10136
Reference
PMID:28626997
  Authors
Zhu Q, Liu X.
  Title
Discovery of a Calcium-Dependent Enzymatic Cascade for the Selective Assembly of Hapalindole-Type Alkaloids: On the Biosynthetic Origin of Hapalindole U.
  Journal
Angew Chem Int Ed Engl 56:9062-9066 (2017)
DOI:10.1002/anie.201703932

KEGG   Addendum: APB62246
Entry
APB62246          CDS       T10000                                 
Symbol
famC4
Name
(KEGG) hapalindole U synthase subunit (EC:5.5.1.36)
  KO
K22971  hapalindole H/12-epi-hapalindole U/12-epi-fischerindole U/hapalindole U synthase [EC:5.5.1.31 5.5.1.32 5.5.1.33 5.5.1.36]
Taxonomy
TAX:56108
  Lineage
Bacteria; Bacillati; Cyanobacteriota; Cyanophyceae; Nostocales; Hapalosiphonaceae; Fischerella
Organism
Fischerella ambigua
SSDB
Motif
Pfam: HpiC1-like DUF5915
Other DBs
NCBI-ProteinID: APB62246
GB: KX451322
UniProt: V5TDH6
LinkDB
AA seq 239 aa
MLSKLVEEQKLMKQNLIVVVTVFLIYICFTINTPANAANVIPIPINNPGFEDPFLKVKDE
FTLETPTNWTMYNPDGLIPEKPTNSTSYLGVTNAFPRSAFYDQHAPEGRNIGSVYLIQKS
GSGIAGLEQTLDATLEPNTKYTLMVDIGNAADSFKDISLAVFPGYRVELLAGDTVLAADE
NTISIEEGGFKTSTVTFTTKPNTPLLGQKLGIRLINLLQSSSANIDFDNVRLTAQPTNI
Reference
PMID:26629885
  Authors
Li S, Lowell AN, Yu F, Raveh A, Newmister SA, Bair N, Schaub JM, Williams RM, Sherman DH
  Title
Hapalindole/Ambiguine Biogenesis Is Mediated by a Cope Rearrangement, C-C Bond-Forming Cascade.
  Journal
J Am Chem Soc 137:15366-9 (2015)
DOI:10.1021/jacs.5b10136
Reference
PMID:28626997
  Authors
Zhu Q, Liu X.
  Title
Discovery of a Calcium-Dependent Enzymatic Cascade for the Selective Assembly of Hapalindole-Type Alkaloids: On the Biosynthetic Origin of Hapalindole U.
  Journal
Angew Chem Int Ed Engl 56:9062-9066 (2017)
DOI:10.1002/anie.201703932

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