KEGG   Addendum: BAC57030
Entry
BAC57030          CDS       T10000                                 
Symbol
mycAIII
Name
(KEGG) protomycinolide IV synthase 3
  KO
K24560  protomycinolide IV synthase 3
Taxonomy
TAX:28040
  Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Micromonosporales; Micromonosporaceae; Micromonospora
Organism
Micromonospora griseorubida
SSDB
Motif
Pfam: ketoacyl-synt Acyl_transf_1 Ketoacyl-synt_C KR PKS_DH_N PS-DH KAsynt_C_assoc PP-binding ADH_zinc_N_2 SpnB_Rossmann Thiolase_N ADH_zinc_N ADH_N Docking adh_short ACP_syn_III Epimerase GDP_Man_Dehyd
Other DBs
NCBI-ProteinID: BAC57030
GB: AB089954
UniProt: Q83WE8
LinkDB
AA seq 3649 aa
MTANNEEKLREYLRRALADLHEARAQVHRLTEEAHEPVAIVGMGCRFPGGVETPEQLWEL
VASGTDAISPFPTDRHWDVDGIFDPEPGRAGRTYCREGGFLVDAPGFDAGFFGVSPREAV
AMDPQQRLLLEVSWEALERAGFDPLALRGSRTGVYAGVMHHDYGLNHSFDEETGGFLGIG
TAGSVVSGRVSYVLGLEGPAVTVDTACSSSLVALHLAVQALRSGECDVALAGGVTVMATP
GIFVEFSRQGGLAVDGRCKAYSDSADGTGWSEGVGVLVVQRLSDAVAAGRRVLAVVRGSA
VNQDGASNGLTAPSGPSQQRVIRAALASARLSVGDVDVVEGHGTGTRLGDPIEAQALLAT
YGCRGGGRSLLLGSVKSNIGHAQAAAGVAGVVKMVLAMERGVVPASLHVGVPSSHVDWSS
GAVEVVGEACAWPETGRPRRAAVSSFGVSGTNAHVILEQAPVADAASFVVVPVSVASGAD
SSGGVAPVSDVSDAGSSSVAVPWVLSARSEWGLRAAAGRLEAALSGPLSGSGSGSGAVSG
VDVGWSLGGRSVFGWRGVSLSGVGGLGVLAGGGVGSGVVVGSGRVASGGVVFVFPGQGAQ
WVGMARGLLAESEVFSEAFDEVGGVVQGLVDWPVRATACGESGGGHLGRVDVVQPLSFVV
MVALAGLWRSWGVVPHGWVGHSQGEIAAAVVSGALSVEEGARVVVGRSRVIGARLAGGGA
MVSVGASVGVVEGLLGGLGGGLEVAVVNGPGQVVVAGDVGGVEGLLVRCGEVGVRARLLP
VGYGSHCGLVDVVRDELLSVLGEVRAGESVIPFYSSVDVGVVDGGVLDGGYWFRNLRLRV
RFGEVVRRLVGDGFSSFVEVSAHPVLVGAIEDVWGEVGGGVGSCVVGSLRRGDGGLGRMV
VSAAEGWVRGLPVQWRRVPVLGGGRQVGLPTYPFQHDRYWLAPTTPATDPRPQQDDLRYR
VRWQPVRMERTARLTGRWVLLLPDRLPATDRDIADRVARTMANAGADVDEIVVDATTVSG
ESLEASLVGAAGVLSALALVEEEHPEFPILPVGLAATLTLLRSLAVAGAPLWTLTRNAVA
ALPGEVPHLAGAQVWALGRVAALELPSPWGGLIDLPTEPNQQVLKRLVGVLAQNAEDQVA
VRNPAAYGRRLVPAPAVREESSWQPQGTVVVVGDTGAPEIERMIHRLRDEGVEVVDADRD
TLGTVLAEHASITVVVAPPAVPVAPLAETTLAGFAATVEAKTGDARWLERLPDTPALQAV
ILFSSVSGVWGGVGQAGYAAGCAYLDALAERLRAGGVSATSIAWTPWEGTSGADVVSRGG
VVPLDAERALDVLFRALRSGRSETVIADIDWDLFLPSFTMARPTVLFDEIPEVRQLREAG
AERPETPRVDSAFSRSLIGLAPADQRRMVDDLLATHIAAVLGESSFAVDAERAFRDIGFT
SVSAVDLRNRLGAATGLTLPASLVFDYPNPQALVDYLLAELTNQSAEQEDVRPTEKVDEP
IAIVGMGCRFPGGVSSPEDLWDVVASGVDAVSPFPVDRGWDLESLFDGDPDRAGTTYCRE
GGFLDDVAGFDAGFFGVSPREAVAMDPQQRLLLEVSWEALERAGHDPRELRGSRTGVYMG
TNGQHYLPLLRDSEEDFDGYFGTGNSASLMSGRISYVLGLEGPAVTVDTACSSSLVALHL
AVQALRSGECDLALVGGATVMATPDVLTEFSRQRALSADGRCKAFSDAADGFGASEGVGV
LVVQRLSDAVAAGRRVLAVVRGSAVNQDGASNGLTAPSGPSQQRVIRAALASARLSVGDV
DVVEGHGTGTRLGDPIEAQALLATYGRRGGGWPLLLGSVKSNIGHAQAAAGVAGVVKMVL
AMERGVVPASLHVGVPSSHVDWSSGAVEVVGEACAWPETGRPRRAAVSSFGMSGTNAHVI
LEHVATEQPAADPEPSVSVGDSDSVVPWVLSARSEWGLRAAAGRLEAALSGPLSGSGSGS
GAVSGVDVGWSLGGRSVFGWRGVSLSGVGGLGVLAGGGVGSGVVVGSGRVASGGVVFVFP
GQGAQWVGMARGLLAESEVFSEAFDEVGGVVQGLVDWPVRATACGESGGGDLGRVDVVQP
LSFVVMVALAGLWRSWGVVPQAVVGHSQGEIAAAVVSGAWSVEEGARVVVGRSRVSGARL
AGGGAMVSVGASVGVVEGLLGGLGGGLEVAVVNGPGQVVVAGDVGGVEGLLVRCGEVGVR
ARLLPVGYGSHCGLVDVVRDELLSVLGEVRAGESVIPFYSSVDVGVVDGGVLDGGYWFRN
LRLRVRFGEVVRRLVGDGFSSFVEVSAHPVLVGAIEDVLGEVGGGVGSCVVGSLRRGDGG
LGRMVVSAAEGWVRGLPVQWRRVPVLGGGRQVGLPTYPFQHDRYWYTGPSRRGDLTSAGL
AEANHPLLAAAVDLPDDHGLVFTGRLSRASVPWLADHALLGVSVLPGTAFVEMALWAGRR
AGFGQLEELTLTTPLPLPESGAQLLVRIDTVDGSGDRTITFHSRVPGDDGSERWTKHAQG
TLVTPTGSARDQAEWKYPDGPDLSVEEFYTRLAERGYHYGPVFRGLRGVRRAGEDVFAEV
ALPQEADGSRFGLHPALLDAAVQAMGLGGFFPDDGQIRVPFSVRGVRLHTTGVERLRVRV
SRSAEDAVRVDCVDEQGRPVCEIDSLVVRAIDTDQLVEDARTPVGELLYRVDWPLLTVGP
AQPPKHCAVVGDDPYGLAAVLGDQGVTCDVHPDVAAFTIRSVTMPDVVVATLPASTDPDV
PAVRDVANRALDLAQWWLSVATDAEAARLVVVTSGAVATQRGEPLRDPAAAAAWGLLRSA
QAEDPGRLVLLDVAGQRPDGAALLAALASGKPQLALRDGNLRVPRLTRTETGDALLPPAG
TSAWRLAVGENATLADLCLEPADTATVSLLPGQVRIAVRAAGLIFRDTLIALGVYPDQAA
MGAEGAGVIVEVGPEVAGLAVGDRVFGLWDRALATHVVVDHRTVVAMPSGWSFAEAATVP
AVFLSAYYALKHLARAVPGQSILVHAAAGGVGMAALQLARHLGLEVYGTASPGKWDVLRD
QGFDDRHIANSRTLDFADRFLDASGGRGVDIVLNSLAGGFVDASLRLLPRGGRFLELGKT
DVRDADRIAAEQPGVTYRAFELMEAGPDLLGEMLRELLVLFDTGVLRPLPLFAHDIRHAR
DAFRTLSQGRHVGKLVLTMPATIDPGGTVMITGGTGNVGGVLARHLVERVRRYGTCRSSS
RQGPAAPGVDDLVAELADLGATVTVHAGDVADRAEVERLVAAVPAEHPLTAVVHAAGTLD
DGMIPSLDQEQVGRVLRPKADGALYLHELTRGSALSAFVLFSSVAAVLGGPGQGSYAAAN
GFLDAFAQNRSAAGLPTVSLSWGLLAGAARMTAHVDQDALRRRMSRGGILPLSGRDLTAL
FDAALAGTEAHQVPVRIDPSAIPDDAGVSPLLRGLAAGRPARAVASEPVDVRSLVERLTG
MPEEAQQTLLENLVRTHAAAVLGYDGPDAIQGDTAFMEIGVDSLAAVDVRNRLAAATGLR
LAASTDFDHPTPVVLAGHLRAQLGLETRTVPLVGELERLTEALGSTSLVDIDPDDRREIA
ARFTALHARWLEMQQAEKPAKDTELTVDDIDAADDDAIFAYLDDRLSDS
Reference
PMID:12583909
  Authors
Anzai Y, Saito N, Tanaka M, Kinoshita K, Koyama Y, Kato F
  Title
Organization of the biosynthetic gene cluster for the polyketide macrolide mycinamicin in Micromonospora griseorubida.
  Journal
FEMS Microbiol Lett 218:135-41 (2003)
DOI:10.1111/j.1574-6968.2003.tb11509.x

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