Entry
Symbol
gra-orf6
Name
(KEGG) ketoreductase RED2
KO
K14633 ketoreductase RED2 [EC:1.1.1.-]
Taxonomy
Lineage
Bacteria; Bacillati; Actinomycetota; Actinomycetes; Kitasatosporales; Streptomycetaceae; Streptomyces; Streptomyces violaceoruber group
Organism
Streptomyces violaceoruber
Taxonomy
SSDB
Ortholog Paralog GFIT
Motif
Motif
Other DBs
LinkDB
All DBs
AA seq
249 aa AA seq DB search
MATDAPEAPVALVTGSSSGIGQTVAQRLAAEGYRVVVNSARSVEDGEKTAAALPDALYVR
ADVSEEADARRLVDTAVEHYGRLDVLVNNAGRTRAIPHADLAAATPEVWREILGLNVIGT
WQTTVAAMPHLARSGNGSVVNVSSIAGSRPAGSSIPYAVSKAAIEHMTRLLANTVGPAVR
VNAVAPGLIETPWTQNSDFFAPIAEHVRQTTPLRRTGRPEDVAEAVLGLVRATYTTGQVL
LVDGGAHLL
Reference
Authors
Ichinose K, Bedford DJ, Tornus D, Bechthold A, Bibb MJ, Revill WP, Floss HG, Hopwood DA
Title
The granaticin biosynthetic gene cluster of Streptomyces violaceoruber Tu22: sequence analysis and expression in a heterologous host.
Journal
Reference
Authors
Taguchi T, Kunieda K, Takeda-Shitaka M, Takaya D, Kawano N, Kimberley MR, Booker-Milburn KI, Stephenson GR, Umeyama H, Ebizuka Y, Ichinose K
Title
Remarkably different structures and reaction mechanisms of ketoreductases for the opposite stereochemical control in the biosynthesis of BIQ antibiotics.
Journal