Entry
Symbol
CYP106A2
Name
(KEGG) steroid 15beta-monooxygenase (EC:1.14.15.8)
KO
Taxonomy
Lineage
Bacteria; Bacillati; Bacillota; Bacilli; Bacillales; Bacillaceae; Priestia
Organism
Priestia megaterium
Taxonomy
SSDB
Ortholog Paralog GFIT
Motif
Motif
Other DBs
Structure
PDB PDBj
LinkDB
All DBs
AA seq
410 aa AA seq DB search
MKEVIAVKEITRFKTRTEEFSPYAWCKRMLENDPVSYHEGTDTWNVFKYEDVKRVLSDYK
HFSSVRKRTTISVGTDSEEGSVPEKIQITESDPPDHRKRRSLLAAAFTPRSLQNWEPRIQ
EIADELIGQMDGGTEIDIVASLASPLPIIVMADLMGVPSKDRLLFKKWVDTLFLPFDREK
QEEVDKLKQVAAKEYYQYLYPIVVQKRLNPADDIISDLLKSEVDGEMFTDDEVVRTTMLI
LGAGVETTSHLLANSFYSLLYDDKEVYQELHENLDLVPQAVEEMLRFRFNLIKLDRTVKE
DNDLLGVELKEGDSVVVWMSAANMDEEMFEDPFTLNIHRPNNKKHLTFGNGPHFCLGAPL
ARLEAKIALTAFLKKFKHIEAVPSFQLEENLTDSATGQTLTSLPLKASRM
Reference
Authors
Rauschenbach R, Isernhagen M, Noeske-Jungblut C, Boidol W, Siewert G
Title
Cloning sequencing and expression of the gene for cytochrome P450meg, the steroid-15 beta-monooxygenase from Bacillus megaterium ATCC 13368.
Journal
Reference
Authors
Lisurek M, Kang MJ, Hartmann RW, Bernhardt R
Title
Identification of monohydroxy progesterones produced by CYP106A2 using comparative HPLC and electrospray ionisation collision-induced dissociation mass spectrometry.
Journal
Reference
Authors
Lisurek M, Simgen B, Antes I, Bernhardt R
Title
Theoretical and experimental evaluation of a CYP106A2 low homology model and production of mutants with changed activity and selectivity of hydroxylation.
Journal