Anopheles gambiae (malaria mosquito): 1275381
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Entry
1275381 CDS
T01036
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial isoform X1
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
aga
Anopheles gambiae (malaria mosquito)
Pathway
aga00790
Folate biosynthesis
aga01100
Metabolic pathways
aga01240
Biosynthesis of cofactors
aga04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
aga00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
1275381
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
1275381
Enzymes [BR:
aga01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
1275381
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
UPF0146
Mur_ligase_C
RILP
Motif
Other DBs
NCBI-GeneID:
1275381
NCBI-ProteinID:
XP_558004
UniProt:
Q5TSB4
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Position
2:63735793..63738470
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AA seq
530 aa
AA seq
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MFRIADFTVRWRKMMNKFTCETASISLLHVSSVKSHLLSTMKGSNVASTLDESYENAISS
LNSLQSNSSVLQDSILRKHSEDNKHINDTLKYLLRIGVSMDHLNQLPVIHVSGTKGKGST
CAMIESILRSNGYRTGFFSSPHLVSVKERVRLNGMPLSSDKFRLYFWKIYKQLLAYREHS
RDMPSYFCFLTILALDVFLRESVDVCVIEVGIGGRYDCTNVLPKTGTVGITSLGLEHTKL
LGNTLEEIAWQKAGIIKRGSDVFSVVQPSECMEIIREECRKLKANLFVVPSELKAYQWAK
KPELVNESCDILDILELNTSLAIQIATNWMNKNISEISQENITSIVTKQTVEGIDRCFWP
GRLQRILYDTKKTLYLDGAHTLESIHLCARWYNMKSHSQYKRLLIFNTTGDRDSAKLLST
LSSMIKFDAAFFTPSVPRDTVTCVDAMNHNFPFELQLQRCRQNYEYWSQTIQHKEGFLHE
SIESVFKQIDEDFVFKGETCDILITGSIHLIGAAFVALNLERFMCTSTTQ
NT seq
1593 nt
NT seq
+upstream
nt +downstream
nt
atgttccgtattgctgattttactgtgaggtggagaaaaatgatgaataaatttacatgt
gaaacggcttcgatttctttgttgcatgtttctagcgttaaatcgcacctattgtcaaca
atgaaaggttccaacgttgcatctactctagacgagagctacgagaatgcaatttcttca
ttaaactcattacaatccaactccagcgttcttcaagattcaattcttcgaaaacatagt
gaagacaataagcatataaacgacacgctcaagtatttgttgcgtattggtgtttccatg
gatcatttgaaccaacttcctgtgatacacgtgtctggaacaaagggaaagggatctact
tgtgctatgatagaatcaattttgaggtcaaatggttatcgtaccggattttttagttcg
ccgcatctagtttcggttaaagaacgtgttcgacttaacggaatgcctctatcgagtgat
aaatttcgtttatatttttggaaaatttataaacaattacttgcatatcgagagcatagc
agagatatgccgtcatatttttgtttcttgacaattttggccttggatgtgtttctacga
gaaagtgttgatgtatgcgtcattgaggtgggcatcggaggtagatatgactgtacgaat
gttttacctaaaactggtaccgtaggtataacttcgcttggtttggagcacacaaaactg
ctgggcaatacattagaagaaattgcatggcagaaagctggtataataaaacgtggctct
gatgtgttttcagttgttcaaccctctgagtgtatggaaattataagggaagaatgtcgt
aagttaaaggcaaatctgttcgtcgtaccatcagaattaaaagcataccagtgggctaag
aaaccagaattggttaacgaatcgtgtgatatccttgatattcttgaattgaacacctca
ttagctattcagatagctacaaattggatgaacaagaatatttccgaaatatcacaagaa
aacataacatcaattgttacaaaacaaacagtggaaggcattgaccgctgtttctggccg
ggaaggttgcagaggatactgtatgatacaaaaaagacactttatctcgatggagctcat
accttagaaagcatacatttatgtgcccgatggtataatatgaaatcccatagccaatac
aaacgacttctgatttttaataccacaggagacagagactcagcaaagctactttctact
ctttcgtctatgatcaaattcgacgctgcattttttactcctagtgttcctcgcgataca
gtgacgtgcgtagatgctatgaatcataattttccattcgagcttcaattacagcggtgc
aggcaaaattatgaatattggagtcagacaattcaacataaagagggtttcctacatgaa
tcaattgaatctgttttcaagcaaatcgatgaagactttgtatttaaaggtgaaacctgc
gatattttaattactggttcgattcatttgataggagccgcattcgtagctctaaattta
gagagatttatgtgtacatctactacgcaatga
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