Anopheles gambiae (malaria mosquito): 1278437
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Entry
1278437 CDS
T01036
Name
(RefSeq) probable pyruvate dehydrogenase E1 component subunit alpha, mitochondrial isoform X2
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
aga
Anopheles gambiae (malaria mosquito)
Pathway
aga00010
Glycolysis / Gluconeogenesis
aga00020
Citrate cycle (TCA cycle)
aga00620
Pyruvate metabolism
aga00785
Lipoic acid metabolism
aga01100
Metabolic pathways
aga01200
Carbon metabolism
aga01210
2-Oxocarboxylic acid metabolism
Module
aga_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
aga00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
1278437
00020 Citrate cycle (TCA cycle)
1278437
00620 Pyruvate metabolism
1278437
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
1278437
Enzymes [BR:
aga01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
1278437
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Motif
Pfam:
E1_dh
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
1278437
NCBI-ProteinID:
XP_318026
UniProt:
Q7Q2S3
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Position
2:67186843..67189518
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AA seq
397 aa
AA seq
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MLSNVAKSIGQRNLFGKLKTLSSQQQNGFASEATFETRAFKLHNLEEGPSTKVTLTKEDA
LKYYGQMYTIRRMETAAGNLYKEKVIRGFCHLYSGQEACAVGMRAAMRPEDSCITAYRCH
GWTYLMGVSPVGVLAELTGRSSGCARGKGGSMHMYGKNFYGGNGIVGAQVPLGVGIGFAA
KYNGTQGACIALYGDGAANQGQLFEVYNMAKLWNAPCIFVCENNGYGMGTSAERASANTN
YYTRGDFVPGIWVDGMDVLAVREATRFALEHTSSGKGPILMETATYRYSGHSMSDPGTSY
RSRDEIAEVRQTRDPITSLREKILTTELATVEELKEIEGKIRAEVDSATKVAKTDKEISV
DELTADIYANPENLTSVRNTVPHAELQHKRLGQAVNM
NT seq
1194 nt
NT seq
+upstream
nt +downstream
nt
atgctttcgaacgtagcaaaatcgattggccagcgcaatctgtttggcaagttgaaaaca
ctttcaagccagcagcagaatggatttgcttcggaagctacgttcgagacgcgggccttt
aagctgcataaccttgaagaaggaccttcgaccaaggtgacactcaccaaggaggatgct
ctgaaatactacggccagatgtacacgataagacgcatggaaacggctgccggcaacctg
tacaaggaaaaggtgatccgaggcttttgtcatctgtactctggccaggaggcgtgtgcc
gttggaatgcgtgcggctatgcgtcccgaggattcctgtatcaccgcgtaccggtgccac
ggatggacgtatctgatgggtgtgtctcccgtgggcgtactggctgagctaacaggccgt
agcagcggctgcgctcgaggtaagggtggcagcatgcacatgtacggtaagaacttctac
ggcggaaatggtatcgtcggagctcaagtaccactaggtgtcggtatcggcttcgctgct
aaatacaacggaacccagggagcctgcattgcgctgtatggcgatggagctgccaaccag
ggtcagctgtttgaggtgtacaacatggcaaagctgtggaacgcaccttgcatattcgtc
tgcgagaacaatggttacggaatgggtaccagcgctgagcgtgcgtctgccaacaccaac
tactatactcgtggagactttgtgcccggtatctgggtcgacggtatggacgtgttggca
gttcgcgaagccacccgcttcgcgttggaacacacctcctccggcaagggaccaattctg
atggaaacggccacttaccgttactctggacattccatgtccgaccccggcactagctat
cgctcgcgcgacgaaatcgccgaagtaagacaaactcgagatccgataacatcgctacgc
gaaaagattttaacgaccgagctggccacggtggaagagctgaaggagattgaaggcaag
attcgtgctgaggtagactcggcgacaaaggtggccaagaccgacaaagaaatctccgtc
gatgagcttaccgcagatatttatgccaatccagaaaacctcacgtccgtacgcaacaca
gtgccccatgccgaactgcagcacaagcggcttggacaggcggtcaacatgtaa
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