KEGG   Astur gentilis (Northern goshawk): 126038617
Entry
126038617         CDS       T08649                                 
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2 isoform X1
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
agen  Astur gentilis (Northern goshawk)
Pathway
agen04010  MAPK signaling pathway
agen04012  ErbB signaling pathway
agen04020  Calcium signaling pathway
agen04510  Focal adhesion
agen04520  Adherens junction
agen04530  Tight junction
Brite
KEGG Orthology (KO) [BR:agen00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    126038617
   04012 ErbB signaling pathway
    126038617
   04020 Calcium signaling pathway
    126038617
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    126038617
   04520 Adherens junction
    126038617
   04530 Tight junction
    126038617
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:agen01001]
    126038617
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:agen04147]
    126038617
   04090 CD molecules [BR:agen04090]
    126038617
Enzymes [BR:agen01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     126038617
Protein kinases [BR:agen01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   126038617
Exosome [BR:agen04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   126038617
CD molecules [BR:agen04090]
 Proteins
  126038617
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 Protocadherin ABC1 Haspin_kinase Tcell_CD4_C Adeno_E3_CR2 CD34_antigen EphA2_TM DUF5849
Other DBs
NCBI-GeneID: 126038617
NCBI-ProteinID: XP_049656536
LinkDB
Position
5:45725114..45735665
AA seq 1238 aa
MKLLRPSSPESHYETLRHLYQGCQVVQGNLELTYLPPDADTTFLKDIKEVQGYVLIAENQ
VSRLELQSLRIIRGTQLFQERYALTVVGNAGPAGTPGLRQLGMRHLTEILKGGVRIEKNP
QLCFQETILWSDIFHRHNELRGETRVESTRNRSCPDCRALCAEGRCWGEGPQDCQTLTNS
ICHGCPRCKGTKPTDCCHEQCAAGCTGPKHSDCLACLNFNRSGICELHCPPLVIYNSDTF
ESVPNRDGRYTFGASCVSQCPYNYLATEVGSCTLVCPQNSQEVTVNNVQKCEKCSKPCPE
VCYGLGVDFLKGVRAVNASNIQHFAGCTKIFGSLAFLPETFAGDPSTNTPPLDPKLLRIF
ESLEELTGFLYIAAWPPDLQDLGVFQNLRVIRGRVLHNGAYSLTLRDLAVRALGLRALQE
ISSGMVLVHHNPQLCFLQKVPWGSIFRNPRQRLFQTHNKPPEQCESEGLVCFHLCAHGHC
WGPGPTQCVACERFLRGQECVASCNLLDGAVREHANGTRCLPCHPECQPQNGTETCFGSV
RMGRDVGGWPWTPGSLTTPPPPSPQEADQCVACAHYKDAQQCVRRCPSGVKADASFVPVW
KYPDEDGVCQLCPTNCTHSCTIRDEDGCPVDQKPSQVTSIIAGVVGALLVVVLLLITVVC
VKRRRQQERKHTMRRLLQETELVEPLTPSGALPNQAQMRILKETELKKVKVLGSGAFGTV
YKGIWIPDGESVKIPVAIKVLRENTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTV
QLVTQLMPYGCLLDYVRENKDRIGSQDLLNWCVQIAKGMSYLEEVRLVHRDLAARNVLVK
SPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWE
LMTFGAKPYDGIPAREIPDLLEKGERLPQPPICTIDVYMIMVKCWMIDSECRPKFRELVT
EFSRMARDPQRFVVIQNDMVGLPGSIDSTFYRALLEEEDMDDLVDAEEYLVPHQGFFSAE
TSTTYRSRISSTRSTAETPADVEEGEGLAAFPFPPQGLAEGPESPVPEVPEGDGGVKASL
QSPSVREPSTLPRYSEDPTGLTAEESEGLDPEGFTAPAPRTAMPEYVNQAGERRSPPRHP
RAPPSPPDKPKGHQGKNGLIKEAKHPFPGPFGHAVENPEYLAPPGPPAPGPFSQAFDNPY
YWNQDPPKTGGPEGGPGMTSTAENPEYLGLAGPDNTAA
NT seq 3717 nt   +upstreamnt  +downstreamnt
atgaagctgctgcgtccctccagccccgaaagccactacgagaccctgcggcacctctac
cagggctgccaggtggtgcagggcaacctggagctcacctacctgccccccgacgccgac
accaccttcctcaaggatatcaaggaggtgcagggctacgtgctgatcgcggagaaccaa
gtgagccggctggagctgcagagcctgcgcatcatccgggggacgcagctcttccaggag
cgttacgccctgaccgtggtgggcaacgccggccccgccggcacgccggggctgcgccag
ctcggcatgcggcatctcacagagatcctgaaggggggggtgcgcatcgagaagaacccc
cagctctgcttccaggagaccatcctgtggtccgacatcttccaccggcacaacgagctc
cgcggagagacccgggtggagagcacccgcaaccgcagctgtcccgactgccgggcgttg
tgtgccgaggggcgctgctggggcgaggggccgcaggactgccagacgctaaccaacagc
atctgccacggctgcccacgctgcaagggcacgaagccgacggactgctgccacgagcag
tgtgctgccggctgcaccggccccaagcactccgactgcctggcgtgcttgaacttcaac
cggagcgggatctgcgagctgcactgtccccccctcgtcatctacaactcggacaccttc
gagtcggtacccaaccgcgacgggcgatacaccttcggtgccagctgcgtcagccagtgt
ccctataactacctcgcaacagaggtggggtcctgcaccctcgtgtgcccccagaacagc
caggaggtcacagtcaacaacgtccagaaatgcgagaagtgcagcaaaccctgcccggag
gtgtgctacgggctgggagtagatttcctcaagggcgtccgtgccgtgaatgcctccaac
atccagcactttgccggctgcaccaagatctttggcagcctggccttcctgcccgagacc
ttcgctggggaccccagcaccaacacgccgcccctggaccccaaactgctgcggatcttc
gagagcctggaagagctgacgggcttcctctacatcgctgcctggccgcccgatttgcag
gacctgggcgtcttccaaaacctgcgggtcatccggggtcgtgtgctgcacaacggcgcc
tactcgctgacgctgcgggacctggcggtgcgggcgctggggctccgtgccctgcaggag
atcagcagcgggatggtgctcgtccaccacaacccccagctctgcttcctccagaaggtc
ccatggggcagcatcttccgtaacccccgccagcgcctcttccagacccacaacaagccc
cccgaacagtgcgagagcgaggggctggtctgcttccacctctgcgcccacgggcactgc
tggggccccggtccgacccagtgcgtcgcctgcgagcggttcctgcgcggccaggagtgc
gtcgcctcctgcaacctcctggacggagccgttcgggaacatgccaacgggacgcggtgc
ctgccctgtcaccccgagtgccaaccccagaacggcaccgagacctgcttcggatcggtg
aggatggggagggatgtgggggggtggccctggacccctgggtcccttacaaccccccca
cccccctccccgcaggaggcagaccagtgtgtggcttgcgcccactacaaggacgcgcag
cagtgcgtgcggcgctgccccagcggggtgaaggcggacgcctccttcgtgcccgtctgg
aagtacccggatgaagacggcgtctgccagctctgccccaccaactgcacccactcgtgc
acgatccgggatgaggacggctgtcccgtggatcagaagccaagccaggtgacgtccatc
atcgccggcgtggtgggggctctgctggttgtcgtcctcctgctcatcaccgtcgtctgc
gtcaagcgccggcggcagcaggagcggaagcacaccatgcggcgcctgctgcaggagacc
gagctggtggagccgttgacgcccagcggggccctccccaaccaggctcagatgcggatc
ctgaaggagacggagctcaaaaaagtgaaagtcttaggctccggcgctttcggcaccgtc
tacaagggcatctggatccccgacggagagagcgtgaagatcccagtggccatcaaggtc
ttgcgagagaacacgtcgcccaaagccaacaaggaaatcctggacgaggcttacgtgatg
gcaggggtgggcagcccctacgtgtcccggctgctgggcatctgcctgacctccacggtg
cagctggtgacacagctgatgccctacggctgcctcctggactacgtgcgggagaacaag
gaccgcatcggctcccaggacctgctcaactggtgtgtgcagatcgccaaggggatgagt
tatttggaggaggtgcggctggtgcaccgggacctggccgctcgcaatgtcctcgtcaag
agccccaaccacgtcaagatcaccgacttcgggctggcccggctgctcgacatcgatgag
accgagtaccacgctgacggcggcaaggtccccatcaagtggatggcgctggagtccatc
ctccgccggcgcttcacgcaccagagcgatgtctggagctacggtgtcaccgtgtgggag
ctgatgaccttcggggcgaaaccctacgatgggatccctgcccgggagatccccgacctg
ctggagaagggcgagaggctgccacagccgcccatctgcaccattgacgtctacatgatc
atggtgaaatgctggatgatcgactccgagtgccggcccaagtttcgggagctggtcacc
gagttctcccgcatggcccgggacccccagcgctttgtggtcatccagaacgacatggtc
gggctgcccggctccatcgacagcaccttctaccgcgccctgctcgaggaggaggacatg
gatgacctggttgacgccgaggagtacctggtccctcaccagggcttcttcagcgccgag
acctccaccacctaccgcagccgcatctcctccacgcggagcacggcggagaccccagcc
gacgtggaggagggcgagggcttggccgccttccccttccccccccagggcctggcagag
ggtccggagagtcccgtgccagaggtgccggagggggacggtggggtcaaggcatccctg
cagagcccgtcggtgcgggagcccagcaccctgccgcggtacagcgaggatcccaccggg
ctgacggccgaggagagtgagggcctggaccccgagggcttcaccgcccccgccccccgc
accgccatgccagagtacgtgaatcaggctggggagcggcggtccccaccccggcacccc
cgtgcacccccatccccgccagacaagcccaaagggcaccagggtaagaacgggctcatc
aaggaagccaagcaccctttcccgggacccttcggccatgctgtggagaaccccgagtac
ctggcaccccccggcccgcctgcccccggccccttcagccaggccttcgacaacccctac
tactggaaccaggacccccccaagaccggtggtcctgagggcggccccggcatgacatcc
acggccgagaatcccgagtacctcggcctggccggacctgacaacacggccgcgtag

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