Astur gentilis (Northern goshawk): 126043970
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Entry
126043970 CDS
T08649
Name
(RefSeq) microtubule-associated protein 1A isoform X1
KO
K10429
microtubule-associated protein 1
Organism
agen
Astur gentilis (Northern goshawk)
Pathway
agen03250
Viral life cycle - HIV-1
Brite
KEGG Orthology (KO) [BR:
agen00001
]
09120 Genetic Information Processing
09125 Information processing in viruses
03250 Viral life cycle - HIV-1
126043970
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
agen01009
]
126043970
09183 Protein families: signaling and cellular processes
04812 Cytoskeleton proteins [BR:
agen04812
]
126043970
Protein phosphatases and associated proteins [BR:
agen01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
126043970
Cytoskeleton proteins [BR:
agen04812
]
Eukaryotic cytoskeleton proteins
Microtubules
Tubulin-binding proteins
Microtubule-associated proteins (MAPs)
126043970
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
MAPB1_N
Anti-Pycsar_Apyc1
Lactamase_B_6
Motif
Other DBs
NCBI-GeneID:
126043970
NCBI-ProteinID:
XP_049668982
LinkDB
All DBs
Position
10:complement(26368943..26440421)
Genome browser
AA seq
3250 aa
AA seq
DB search
METTAGPVAMETAAPWLPGGRRRREPRRHALLVVIGEIGTEPERGALRGALERGIRSWNI
NILSCDLNQQLRLFVTRHLAQFSSEVKGQRTLHHRSDTLETVILVNPNVDSIVSEVRSLV
CDSSAHKLLIFCGQSSDQEGDLILQTGTFTYQKFAEILSDPEVTQILSNTDSDIKASLTV
SCLGEGDWSNLGHPRFQEIINLKLNPDPVLPEMDGVSEFAEYVSETVDVPSPFDLLEPPT
SGGFLKLSKPCCYIFPGGRGDSALFAVNGFNILVDGGSDRKSCFWKLVRHLDRIDSILLT
HIGADNLPGINGLLQRKVAEQEEEQSQGSTNYSDWMKNLISPELGVVFFNVPEKLKMPES
SMKVKRSIEEACLTLQYLNRLGIKSEPLYRVVSSTIEPITLFHKMGVGKLDMYILNPVKD
SKEMQFLMQKWAGNSKAKTGIILASGKEGEISVPYLTSITALVVWLPASPTEKIVRVLFP
GNAPQNKILEGLEKLKHLDFLRYPVATQKDITSGIPPPVLKQTKIKQRTDSKESLKSSPK
PSVTKQAKKEEAVEEGIKEVKPEVIKDTKIEKKVKEHSEKIPEKPVKHEKVKTETSDALK
AEKRKLSKDKVGKKHLKEKVSKLEEKKDKEKKEIKKEKKDLKKDDGKKEEKKDSKKEDKK
KETKPEPKKISKPDLKPFTPEVRKTLYKAKVPGRLKTEKIKVKPEKEVPADLKTSPMEKA
PVQVEPGETSIAEQRLVLSSPEDLTKDFEELKHEEKGALQVTQEMSDIEVSDKIMRVPET
EIKDSADMIAQSCLEVDLILKTNIPDQGITTTDMEKESPAEEKAVHQLELRAGHAEEIED
ERRTIDESHDTRYCEGKAEQDKEVQVVPDKEQVPSQTDALAKSVQSSAFREEEKEEEEKI
SLDRKQREAETKTCEKYTDRTETQEEGEKEKREDVIEKAELEEKEGQHMKAEEKVEKNRD
FYELNQDEREDKIFTTTEKEKDFSDMVEKNKLLGKDVTKEESYLSSLPVPAGATAEHVSY
IQDETIPGYSETEQTISDEEIHDEQEERIPHLKYDVNAYDISVPDHPGSFEAIHGIQAMP
TADLSAKGYAGQESEILAYPTNIVAAPLAEEEHISSATSITECDKLSSFATSVAEDQSVA
SITAPQTEETGKSSLLLDTVNSMPSSRTEATQGLDYVPSAGTISPTSSLEEDKCFKSPPP
EDFHALAEGERKLEAQKKDLNEEAEDEEEEEDGTPNIEMPEKLRGHYNAPMFAHQGGPDN
VLISVPTEVVQTSGLPLSTEETPLSQVDSAEAEERCMSPDDSTVKMASPTPSGPTSAGHT
PFHQSPVEEKLETVDSDLFEKQTDAAANKLESQTSVVVKGAKGEPLKEDELSAAKYRNEK
EVPGPVQHKLGFGSDVPVSPGEDVLEEPMGKEELPWLSYHKQDTVVIGEEEEERPMLPHP
STDVFLEPEKEQGTKTMTESLMGFSKHLSFEPFSTTETSLGNVDLPQFTSQSKSESDKSS
QFSPDDTKSLSFTEESIGKEKSSDISVKGATTEEEKLLYFTGDTSEEEKSSHVSIKDISP
EETKSISLTESPSKEISSDLFVKGISPEDIKSLSFTEEIPAKEKTTSDFTDKFPSEAVKS
MDFTEQSPATYEKSLKISAKEFTKEVSKPFPCPESSSVKDTSPRDTSTEEMSPDDSSLFS
ATEKDPLRGRTAGLDSQEVSPDMKGLHFTDSSPSEDKTSSHISTEGVKSCRFKEAQEEKS
PEMEDFYMKDLSYEKKVWFPEEVEETPVQGRRQRYDKERESTFLDEVPEYEKKSLPKMGE
GEILSPAVPGSHSWRKAESEAWGSVYGYLQEGRETGRGGQLPKDEEDEELCHAEDKPVLL
QAEAECLKMESCDYKEDTQKSAKPTSETKKAETVPADITVPERTQMEGSPLSSQYVSGED
NQAKALTANKERQELLLTSKHDYSYLDDEEKAVLDIYAKSLDQALMASPLSVTTTTLEKE
IDTIPETERPYKLDQCRPPLWEEVPSKDTKKSDISGLYQEIDCKYKSDRKQEDDYKSTEG
LYDSTGRKEQMAAASTLLQSTRPAEYEYIAASPEESAAVSGQCAHSPLGQGPCQKSSAAM
GHAEAVGSAGRVAYPPETYSRSSPEPYSYEEGVCRPRGDDSSTRQEQEEREPTPYPDERS
FKYADIYEKIIVSGVGPSPFTAKGADSPGHTDKVPATALISQKGQSFHVSAKEEESCLYT
SAEKELSSPASPKDKADSAFDYTDIHERYLPLSETDKLKISEGQEELKVSSALPEELDSE
LHPSSASTAFASPTDMTDTFYQEKSAAYIDAACPDENIILSSQEQPSLSLKSEIPSPKDT
YYEKAGRGEESMSDSELEKGAKEKSEKESKLHSPVEAAGTVYAHISAMDEFHVSEPLLES
KHQESTSRSSTASSPSDPGWKEEYGGMKTAPATVMGTYVAGYSDLPDIGRDEQASEMCHL
RQDSSQKREVAEKSTKESHSCVTDYPSAAVVSECQEQAIYLKSASGRQKEAYKKDPTVEG
RWMDSSSGFECSLLGKSETSSMFRHEQMSASHLGDISLPLKAPCALLSDQGKKDEYLEVS
EKISSLESSFTKFSPLSPYEEDKLFSKAVERKTVAQQQLKDDSSSLSEEPSSEATTPVIS
TTAESFYSHMLSTHTGAGAEPGTKSLWDVSPQISDNAMKTHTAETKDFVFAEEHGSPFTS
GMGGSISPCRKECQSLQPTPFSAEKQQQPCVSRPEQKAQFAEQLMTLTSLPDVLTSFPHH
QHEDETTANGPTEVSTSLQAFQSTYHAAEAKDEKTRPDSDSSFSPCTGKEDTERQSRPSS
LMSPEHSFQPFFPDVQRGGKPEDHGDASHEMEPRLGGSFDCGQKFSSCEYKHRKGELSPS
FINPSPHELSEDSDLSQEDGHPSVQGRPPHTGSSPMQSATVEETPPTSVSDSGTSQSDSD
VPPETEECPSITADANMDSDEDADFLPVDKAVGNAHHASSRSSHDPQPVPMVDPHPHPPH
PDVCMVDPDMLVNEQSMTRTDKISKKDIKEKNKGVRKPLSKPKSSSPARKLDVKGKRSPT
PVKQPSDKSPKSVTAKKERDGGEKSKPRNALVQPPHTEDELSRSSHSNPGKSLVNGIKTN
PASNSPKSSLPVPMGPPVYVDLAYIPNHCSGKNTDPEFFKRVRASYYVVSGNDAANGEPS
RAVLDALLEGKSQWGENLQVTLIPTHDTEVTREWYQQTHEKQQELNIMVLASSSTVVMQD
ESFPACKIEF
NT seq
9753 nt
NT seq
+upstream
nt +downstream
nt
atggagaccacggccgggccggtcgctatggagacggcagcgccctggctgccgggcggg
cggcgccgccgggagccgcggaggcacgcgctgctcgttgtgatcggggagatcgggacg
gagccggagcggggggcgctgcgcggcgccctggagcgcggaattcgttcctggaacatt
aacattctgtcctgtgacctgaatcagcaactgcgactcttcgtaacccgacacctggct
cagttttcttcagaagtcaaaggccaaagaaccctccatcaccggagtgataccctggag
acagtgatcctggtaaatcccaatgtggacagcatcgtgtctgaggtccgttcactcgtg
tgtgattcatcagcccacaagctactcatcttctgtggtcagagctcagaccaggaagga
gacttgatcctgcagacagggacattcacttaccagaagtttgctgagatactttcagac
ccagaggtcacccagattcttagcaacactgattcagatatcaaggcctcccttactgtg
tcgtgcttgggagaaggagactggagcaaccttgggcatcctcgatttcaggaaattatt
aatctgaaactgaatcctgatccagttctgccagaaatggatggggtgtctgagtttgca
gaatacgtctctgagacagttgacgtgccatctccatttgatctcctggagccacccact
tcagggggctttttgaagctttccaaaccctgctgctacatattccctggtggaagaggt
gattctgctctctttgctgtaaatgggtttaacatccttgtggatggtggttctgacagg
aaatcttgcttctggaagcttgtaaggcacctggataggattgactcaatcctgctcacc
cacattggtgcagacaacctacctggcatcaatgggctgctgcagaggaaagttgctgag
caagaagaggaacaatcccagggctctaccaactacagtgactggatgaagaacctaatt
tctcctgagctaggggtggttttttttaatgttcctgaaaaactgaagatgcctgaatcg
tccatgaaagtaaagaggagcattgaagaagcttgtctgacactgcagtatctcaacaga
ctaggcattaaatcagagcctctctacagggtggtgagcagtaccattgaacctatcaca
cttttccacaaaatgggagtgggtaagctggacatgtatatactgaatcctgtcaaggac
agtaaagaaatgcagtttttaatgcagaaatgggctggtaatagtaaagcaaaaactggc
ataattcttgcaagtgggaaagaaggtgaaatttctgttccctatctcacatccatcaca
gccctagtggtatggcttccagctagcccaacagagaaaattgtaagggttttgtttcct
ggaaatgctcctcaaaataagatactggaaggtcttgagaaactcaagcatctggatttt
ctgaggtacccagtggctactcagaaagatatcacttctggaatacctccacctgtgctg
aagcagaccaaaattaaacaaagaactgacagtaaagagagtcttaaatcttctcccaag
ccatctgtgacaaagcaagctaagaaagaagaggcagttgaggaggggattaaggaggta
aaaccagaagtcataaaggatactaaaattgagaaaaaggttaaagaacactcagagaaa
attcctgagaaacctgttaaacatgaaaaggtaaagacagaaacaagtgatgctctcaaa
gctgaaaaaagaaaattgtcaaaagacaaggttggaaaaaagcatctcaaagagaaagta
tccaaactggaggagaagaaagacaaagaaaagaaagagattaagaaagagaaaaaagac
ttaaaaaaagatgatggaaagaaagaggaaaaaaaagattcaaagaaagaggataaaaag
aaagaaaccaaaccagagcctaaaaaaatttctaaaccagacttaaaaccgtttacccca
gaagtaagaaaaacgttatacaaggcaaaagttccaggcagactcaaaactgagaagatc
aaagtcaaacctgaaaaggaagtacctgctgacttgaagacatcaccaatggagaaggca
cctgtacaggtggagccaggagagacttccatagctgaacagaggttagtcctgtcttca
ccagaagatcttacaaaggactttgaggaactgaagcacgaggagaaaggggccttgcag
gtgactcaggaaatgtctgatattgaggttagtgataagattatgagagtacctgaaaca
gagataaaagactctgctgacatgattgctcagagttgccttgaagtagatctgattttg
aaaacaaacattcctgatcagggaataactactactgatatggaaaaagaatcaccagca
gaggaaaaggcagtccatcagctagaactgagagcaggtcatgctgaagaaatagaggat
gaaagaagaacaatagatgaaagtcatgacacgagatactgtgagggaaaagctgagcag
gacaaggaagttcaggtggttccagacaaagaacaagtaccatcacagacagatgcctta
gcaaagagtgttcagtcatcagcgttcagagaggaagaaaaggaggaagaggagaaaatc
tctttggacagaaaacagagggaagcagaaacaaagacttgtgaaaagtataccgacagg
acagagacacaggaagagggtgagaaggaaaagagagaagatgtgatagaaaaggcagaa
ctggaagaaaaggaaggacagcacatgaaggcagaggagaaggtggaaaagaatagagac
ttctacgagctgaatcaggatgagagggaggacaaaatatttaccactacagaaaaggaa
aaagattttagtgacatggttgagaaaaacaagttacttggaaaggacgtaacaaaggaa
gagtcatatctgagcagtctgccagtcccagcaggagcaacagcagaacatgtttcatat
atccaagatgaaactatcccaggctactcagaaacagagcagaccatctctgatgaagaa
atacatgatgaacaggaagagaggatcccacacttgaagtatgatgtcaatgcctatgac
atttctgttcctgaccacccaggctcttttgaagcaatacatggaatacaggccatgcct
actgctgacctttcagccaagggctatgctggccaggagtctgaaatcctggcatatcct
acaaacattgtggcagcacctctagctgaggaggaacatatatcctctgctacctccatt
acagaatgtgataagctttcatcttttgcaacttcagtagcagaagatcaatcggttgca
tctataacagcaccacaaacagaagagacagggaaaagctctttacttctagacacagta
aacagcatgccctcctctcggactgaagcaacccaaggtctcgactatgttccctctgct
ggcacaatctcccccacatcatccttggaggaagacaaatgttttaaatctccaccccct
gaagatttccatgcattagcagaaggagagagaaaactggaagctcaaaaaaaggatctt
aatgaagaggcagaagatgaagaggaagaagaagatgggactccaaatattgaaatgcct
gagaaactcagagggcattacaatgcccccatgtttgctcatcaaggaggtcctgataat
gtgttaatcagtgttcccacagaagtggtgcaaacttctggtctgccattatccactgaa
gaaacaccgctttcccaggttgattctgcagaggctgaagaacgatgcatgagtcctgac
gatagtacagtcaaaatggcctctcccaccccatctggccccactagtgcaggacacaca
cctttccaccagtctccagtggaggaaaaactagaaacagtagactcagatctatttgaa
aaacaaacagatgctgctgccaacaaattggaaagccaaacttctgttgtggtgaaggga
gccaagggtgaacctctcaaagaagatgagctatctgcagctaaatacagaaatgaaaaa
gaagtgcctggacctgtacagcacaagctgggctttggcagcgacgttccagtgtctcct
ggggaggacgtgctggaagaaccaatgggcaaggaagagctgccctggctctcctaccac
aagcaggacacagtggtgataggggaggaggaggaggagcgtcccatgctgccccatccc
agcacagatgtgtttctggagccagaaaaagagcaaggaactaaaaccatgacagaaagt
ttaatgggattttcaaaacacttgtcctttgagccattctctaccacagaaacatcccta
ggaaatgtggatcttccacagttcacaagccaaagcaaatctgaaagtgacaaatcttca
caattttcaccagatgataccaaatcactttcttttacagaagaaagtattggtaaagaa
aaatcctcagatatttctgttaagggagcgactactgaagaagaaaaactgctgtatttc
acaggagacacctcagaagaagaaaaatcttctcatgtttccattaaagacatttctcca
gaagagaccaaatccatttctctcactgagagtcccagcaaggaaatctcttcagacctt
tttgttaaaggaatttctccagaagacataaaatctcttagtttcacagaagagatacct
gcaaaagaaaaaactacatctgacttcactgacaaattcccttcagaagctgtgaaatcc
atggattttacagagcagagcccagctacatatgaaaaatcactgaaaatttctgccaaa
gaattcacaaaagaagtgtcaaaaccttttccttgcccagaaagtagctcagttaaagac
acgtcacccagagatacttcaaccgaagaaatgtctccagatgacagcagtttattttct
gcaacagaaaaggacccacttaggggaagaactgcaggcttggactctcaggaagtatct
ccagatatgaagggcttacactttacagactctagcccaagtgaggataagacatcttca
cacatttctactgaaggtgtaaaatcttgcaggttcaaggaagctcaagaagaaaaatct
ccagaaatggaagacttttacatgaaagatttaagttatgagaagaaagtgtggtttcca
gaagaggtggaggagacccctgttcagggaaggcggcagagatatgataaagagagagag
agcacattcttggacgaggtaccagaatatgaaaaaaaatcccttcctaaaatgggagag
ggggagatcctatctcctgcagtgcctggcagtcacagctggagaaaagcagaaagtgaa
gcatggggttcagtgtatgggtatcttcaggaaggaagagagactgggagaggagggcag
ttacccaaggatgaggaggatgaggagctctgtcatgctgaagacaaacctgtgctactg
caagcagaagcagaatgtttaaagatggaatcgtgtgattacaaagaagacacacagaag
agtgccaaacctacatcagaaacaaagaaagcagaaacagttcctgctgacatcactgtc
ccagaaagaacacaaatggaaggttctcctctgtcttctcaatatgtctctggtgaggac
aatcaggccaaagcattaactgcaaacaaagaaaggcaagaattgttgttgacatctaaa
catgattactcctacttagatgatgaggagaaagctgtcctagatatctatgcaaagtca
ctagaccaagcactgatggcatctcccctgtctgtaacaactaccactctggaaaaggag
attgacacaataccagaaacagaaaggccttacaagttagatcagtgcaggccaccttta
tgggaagaagtcccatcaaaagacacaaagaaatcagacatcagtggtttgtatcaggaa
atagactgtaaatataagtcagatagaaagcaagaggatgactacaaatccactgagggt
ctttatgactctacaggaagaaaagagcagatggcagcagcatctactctgttgcaatct
acaagaccagcagaatatgaatatatagcagcgtccccagaagaaagtgctgcagtgtca
gggcagtgtgcgcactctcctctaggacaaggcccttgtcaaaaaagcagtgctgccatg
ggccatgctgaggctgtgggttctgctggccgtgtggcatatcctccagagacctattcc
aggagctcccctgagccttattcctatgaggaaggggtctgcagacccagaggtgatgac
agttctacaagacaagagcaagaagagagagaaccaactccctaccctgatgaaagaagt
ttcaagtatgctgacatctatgagaagataattgtgtctggagttggaccctcccccttc
acagccaagggtgcagacagcccaggtcacactgacaaggtaccagcaacagcactgatc
tctcaaaaaggtcaaagttttcacgtctctgcaaaggaagaagagtcctgcctttatacc
tccgctgagaaggagttgtcatcgccagcatcccctaaagataaagcagattcagccttt
gactatacagacatccatgaaagatacttgcccttgtctgaaactgataagcttaagata
tctgaaggacaggaagaactgaaggtgtcttctgctttgccagaagaactagactctgaa
ctgcacccatcatccgcaagcacagcatttgcctctcccacagacatgactgacacgttt
tatcaggaaaaatcagctgcctatattgatgctgcctgtccagatgagaacatcattttg
tctagccaggagcagccatctctgtccctgaaatctgaaatcccaagtcccaaagataca
tactatgagaaagcaggtcgaggggaagaaagcatgagtgactctgagttagaaaaaggc
gccaaggagaaatctgaaaaggagtctaaactgcacagccctgttgaagctgcaggcaca
gtctatgcacacatctcagcaatggacgagtttcatgtatcagaaccccttctggaaagc
aagcaccaggagtccacttcacgcagttccactgcctcttcaccttccgatccagggtgg
aaagaggaatatggaggtatgaaaactgcaccagctactgtcatggggacgtatgttgct
ggctacagtgacctgccagacataggcagagatgagcaggcttcagaaatgtgccattta
agacaagattcttcacaaaagagagaggttgctgaaaaatccacaaaggagtcacattcc
tgtgtaacagattatccaagtgcagctgtggtctcagaatgccaagagcaagccatatac
ttgaaatctgcttccggaagacagaaggaagcatacaaaaaagacccaacagtagaaggc
agatggatggatagctcttctggatttgaatgctccctgctaggaaagagtgaaacatcc
agtatgttcagacatgagcaaatgtcagcaagccatttaggggatatctctcttccttta
aaggctccttgtgctttgctttcagaccaggggaagaaagatgagtacttggaggtttct
gagaaaatcagcagccttgagtcatcttttactaaattctcaccgctaagtccatacgaa
gaagataagttattctccaaagctgtggaaagaaagactgtggcccaacagcagctgaaa
gatgattcttccagcctgtcagaggagccttcatctgaagctaccactcctgtcatatca
actacagcagaaagtttctactcccatatgctttctacacacacgggtgcaggagcggaa
ccaggtaccaagagtctttgggatgtgtctccacagatttccgataatgccatgaaaaca
catacagctgaaaccaaagactttgtgtttgctgaagaacacggttctccattcacaagt
ggcatgggtggcagcatttccccatgcagaaaggagtgccagagtttacagcccacacca
ttctctgcagagaaacaacagcaaccctgtgtaagcaggccagagcagaaggcacaattt
gcagaacagctgatgacgctgacatctctccctgatgtgttgacatcatttcctcatcat
cagcatgaagatgaaaccacagccaatggtccaacagaggtgagcaccagtctgcaagct
ttccaaagtacataccatgcagcagaggcaaaagatgaaaaaacgcgtcctgattctgac
agcagtttttctccatgcacaggcaaagaggacacagagaggcagagccgaccttcctct
ctgatgtcccctgaacacagtttccagccctttttcccagatgtgcagaggggtggaaaa
ccagaggaccatggagatgcttcccatgagatggagccacgtttaggaggcagttttgat
tgtggacagaaattttcctcatgtgaatacaagcacaggaagggagagctctctccctca
ttcatcaacccgagccctcatgagctctctgaagatagtgacctctcacaggaggatggt
catccttcagtgcaaggaagaccacctcacactggtagtagccccatgcaaagtgccaca
gtggaggaaacccctccaacatcagtgagtgattctggaacctcccagtcagactcggat
gtcccgcctgagacagaagaatgtccgtccatcacagcagatgccaacatggactcggat
gaagatgccgatttcctcccagttgacaaagctgttgggaatgctcatcatgccagttct
agatccagccatgatcctcagcctgttccaatggtagatccccatccccatcctcctcac
cctgatgtctgcatggtagaccctgatatgttggtaaatgaacaaagcatgaccagaact
gataaaatttccaagaaagacataaaagaaaagaacaaaggtgtgaggaagcctttgagc
aaacctaaatcttcctcgcctgcccggaaattagatgtgaaagggaaacgatcacccact
cctgtgaaacaaccatcagacaaatctccaaaatctgtcactgccaaaaaagaaagagat
ggaggagagaagtccaaaccacgtaatgcgctggtacagcctcctcacacagaggatgag
ttatcccggagtagtcacagcaaccctggcaagagccttgttaatggcatcaaaacaaac
cctgcttccaatagtcctaagagcagtttgcctgtgcccatgggtccacctgtctatgtg
gacttggcatacatccccaaccattgcagtggaaagaacacagatccggagttcttcaag
cgggttcgagcatcatattatgttgtgagtgggaatgatgcagccaatggagaaccaagc
cgtgcagtgttggatgcactcctggaagggaagtctcagtggggggagaacctgcaggtg
acattgatcccaacacatgatactgaggtgacacgggaatggtaccaacagacccatgag
aaacagcaggagctaaacatcatggtattggcaagcagcagcactgttgtgatgcaggat
gaatcttttccagcctgtaagatcgaattctaa
DBGET
integrated database retrieval system
