Astur gentilis (Northern goshawk): 126046671
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Entry
126046671 CDS
T08649
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit isoform X1
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
agen
Astur gentilis (Northern goshawk)
Pathway
agen00270
Cysteine and methionine metabolism
agen00480
Glutathione metabolism
agen01100
Metabolic pathways
agen01240
Biosynthesis of cofactors
agen04216
Ferroptosis
Module
agen_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
agen00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
126046671
09106 Metabolism of other amino acids
00480 Glutathione metabolism
126046671
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
126046671
Enzymes [BR:
agen01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
126046671
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Motif
Pfam:
GCS
GCS2
SANT_DAMP1_like
Motif
Other DBs
NCBI-GeneID:
126046671
NCBI-ProteinID:
XP_049675331
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Position
16:4525560..4579723
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AA seq
649 aa
AA seq
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MGLLSQGSPLSWEETRRHAEHVRKHGILQFLHIYRALRDRHKDVLKWGDEVEYMLVKFDH
ENKKVRLVLCGEEVLQTLQDKGEKVNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
QDNMRKRRQEAASVLKENEAVCTVTSFPSLDLIVVLHRLGCPGFTLPEYKPTPVEGGASK
SLFFPDEAINKHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFIETFPNDDGEAAKA
AKPDYIYMDAMGFGMGNCCLQVTFQACSISEARYLYDQLATICPIVMALSAASPFYRGYV
SDIDCRWGVISASVDDRTREERGLEPLKNNHYRISKSRYDSIDSYLSECGEKYNDIDLTI
DKDIYEHLIKEGIDHLLAQHIAHLFIRDPLTLFEEKIHLDDANESDHFENIQSTNWQTMR
FKPPPPNSDIGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDENM
KMAQKRDAVRQGMFYFRKDICKGGNTVVDGCGSAQNGTGTDAEEYTLMSIDTIINGKEGV
FPGLIPILNSYLENMEVDVDTRCTILNYLKLIKKRASGHNNSSVCCVKQLGQSQILVIAA
ALLLLTPAGRYQDLPGFRCVGARSWCLRAAVPKIHGALLYCAPPQSLEV
NT seq
1950 nt
NT seq
+upstream
nt +downstream
nt
atggggctgctgtcgcagggctcgccgttgagctgggaggagacgcggcggcacgcggag
cacgtgcggaagcacggcatcctccagttcctccacatctaccgcgccctccgcgatcgc
cacaaggacgtcctcaagtggggcgacgaggtggaatatatgttagtaaaatttgaccat
gagaataagaaagtgcgcttggtgctctgcggtgaagaagttcttcaaacactgcaagac
aagggggagaaggtaaaccccaaccacccaacactctggcgaccagaatatggaagctac
atgatagaagggacgcctgggcagccgtatgggggaaccatgtctgaattcaacacagtg
caagacaacatgagaaaaagacggcaagaggcagcttctgtgctcaaagaaaatgaggct
gtttgtactgtgacgtcgtttccaagcttggatctcattgttgtgttacataggttaggg
tgtcctgggtttacgctgccggaatataagccaacgccagtagaaggaggagcttcaaaa
tcccttttttttccagatgaagccatcaataaacatcctagatttagtacactgaccaga
aacattcggcaccgaagaggagagaaggttgtgataaatgtaccaatatttaaagataaa
aacacgccatcaccgtttatcgaaacgtttcctaatgatgatggagaagcagcaaaggcg
gctaagccagactatatatacatggatgctatggggtttggaatgggaaactgctgtctt
caggtaacattccaggcttgcagcatttccgaagcgaggtatctctatgatcagctagcc
acgatctgtcccattgtgatggcattgagcgctgcatctccattctacagaggctacgtg
tctgatattgactgtcgctggggagtaatctctgcatctgtagatgatcgaacgcgagaa
gagagggggctagagccactgaagaacaaccattatagaatcagtaaatccagatatgat
tccatagacagttatctatctgaatgtggtgagaaatacaatgacattgatttgacaata
gacaaagatatctacgagcacctaataaaggaaggtattgaccaccttttggcacagcat
attgcacacttgttcattcgagacccattgactttgtttgaggagaaaatacatctagat
gatgcaaatgaatccgaccattttgagaatattcagtctacaaactggcagacaatgagg
tttaagccaccccctccaaattcagatattggatggagagtggaattcagacctatggag
gtccagttaacagactttgaaaactctgcatatgttgtgttcgtggtactgctaaccaga
gtgattctgtcatataaactggattttctcattcctttgtccaaggtggatgaaaacatg
aagatggcccagaaaagagatgctgtccggcagggaatgttttacttcagaaaagatatt
tgcaaaggtggaaacactgttgtggatggatgtggctctgcacagaatgggacaggcacc
gacgcagaagagtacaccttaatgagtattgatacaattatcaatgggaaggaaggagtc
tttcctggtttgatcccaattttgaattcctatcttgaaaacatggaagtggatgtggac
acaaggtgcaccatcctaaactacctgaagctaataaaaaagagagcatctggccacaac
aattcctctgtgtgctgtgtaaaacaactcggtcaatctcaaatccttgtgattgccgca
gcgctactcctactgacgcctgcaggtcggtatcaagatctccctgggtttcggtgtgtg
ggtgctcgctcctggtgcctccgagcggcagttcctaaaatccacggagctctgctctac
tgtgctcctccccagagtcttgaagtttaa
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