Astur gentilis (Northern goshawk): 126051404 Help Entry 126051404         CDS       T08649                                  Name (RefSeq) ryanodine receptor 2 isoform X1   KO K04962   ryanodine receptor 2 Organism agen  Astur gentilis (Northern goshawk) Pathway agen04020   Calcium signaling pathway agen04260   Cardiac muscle contraction agen04261   Adrenergic signaling in cardiomyocytes agen04371   Apelin signaling pathway Brite KEGG Orthology (KO) [BR:agen00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     126051404    04020 Calcium signaling pathway     126051404  09150 Organismal Systems   09153 Circulatory system    04260 Cardiac muscle contraction     126051404    04261 Adrenergic signaling in cardiomyocytes     126051404  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04040 Ion channels [BR:agen04040]     126051404    04990 Domain-containing proteins not elsewhere classified [BR:agen04990]     126051404 Ion channels [BR:agen04040]  Voltage-gated cation channels   Ryanodine receptor    126051404 Domain-containing proteins not elsewhere classified [BR:agen04990]  EF-hand domain-containing proteins   Other EF-hand domain-containing proteins    126051404 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  RYDR_Jsol RYDR_ITPR RyR RR_TM4-6 SPRY Ins145_P3_rec MIR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 EF-hand_8 EF-hand_6 Motif Other DBs NCBI-GeneID:  126051404 NCBI-ProteinID:  XP_049686547 LinkDB All DBs Position 28:complement(9474208..9926312) Genome browser AA seq 4965 aa AA seqDB search MAEGGEGEDEIQFLRTDDEVVLQCTATVHKEQQKLCLAAEGFGNRLCFLESTSNSKNVPP DLSICTFVLEQSLSVRALQEMLANTEEKAEGLVDVEKWSAQGGGHRTLLYGHAILLRHSY SGMYLCCLSTSRSSMDKLAFDVGLQEDTTGEACWWTIHPASKQRSEGEKVRVGDDLILVS VSSERYLHLSYGNGSLHVDAAFQQTLWSVAPISSGSEVAQGYLIGGDVLRLLHGHMDECL TVPSGEHGEEQRRTVHYEGGAVSIHARSLWRLETLRVAWSGSHIRWGQPFRLRHITTGKY LSLLDDKSLLLTDKEKADVKSTAFCFRSSKEKLDTGTRKEVDGMGAPEIKYGDSICFIQH VDTGLWLTYQSADAKSVRMGSVQRKAIMHHEGHMDDGLTLSRSQNEESRTARVIRSTVFL FNRFIRGLDALSKKAKSSTVDLPIESVSLSLQDLIGYFHPPDEHLEHEDKQNRLRALKNR QNLFQEEGMINLVLECIDRLNVYSSAAHFADVAGKEAGEAWKSILNSLYELLAALIRGNR KNCAQFSGSLDWLISRLERLEASSGILEVLHCVLVESPEALNIIKEGHIKSIICLLDKHG RNHKVLDVLCSLCVCHGVAVRSNQHLICDNLLPGRDLLLQTRLVNHVSSMRPNIFLGISE GSAQYRKWYYELMVDHLEPFVTAESTHLRVGWASTEGYSPYPGGGAEWGGNGVGDDLYSY GFDGLHLWSGCVARTVNSPNQHLLRTDDVISCCLDLSAPSISFRINGQPVQGMFENFNID GLFFPVVSFSAGIKVRFLLGGRHGEFKFLPPPGYAPCFEAVLPKEKLKVEHSREYKQDRS YTRDLLGPTISLSQAAFTPVPVDTSQIVLPPHLERIREKLAENIHELWVMNKIELGWQYG PVRDDNKRQHPCLVEFSKLPEQERNYNLQMSLETLKTLLALGCHVGIADEHAEEKVKKMK LPKNYQLLSGYKPAPMDLSFIKLTPSQEAMVDKLAENAHNVWARDRIRQGWTYGIQQDVK NRRNPRLVPYALLDDRTKKSNKDSLREAVRTLLGYGYNLEAPDQDHAMRLDVCSGIMEKF RIFRTEKTYAVKAGKWYFEFEAVTAGDMRVGWTRPGCLPDQELGSDEEAFVFDGFKAQRW HQGNEHFGRSWLAGDVVGCMVDMNEHTMMFTLNGEILLDDSGSELAFKDFEVGDGFLPVC SLGPSQVGRMNFGKDVSTLKYFTICGLQEGYEPFAVNTNRDITIWLSKRLPQFLPVPQNH EHIEVMRIDGTIDSCPCLKVTQKSFGSQNSKTDVMFFRLSMPIECAEVFSRSAAGGLPGS GLFGPKNDLEDYDADSDFEVLMKTAHGHLVPDRTEREKDATKPELNNHKDYVQEKPSRLK QRFMLRRTKPDYSTSHSARLTEDVLADDRDDYDYLMQTSTYYYSVRIFPGQEPANVWVGW ITSDFHQYDTSFDLDRVRTVTVTLGDEKGKVHESIKRSNCYMVCAGESMSPGQGRNNNGL EIGCLVDAASGLLTFTANGKELGTYYQVEPSTKLFPAVFAQATSPNVFQFELGRIKNVMP LSAGLFKSEHKNPVSQCPPRLHVQFLTHVLWSRVPNHFLKVDVSRISERQGWMIQCLNPL QFMALHIPEENRTIDILELTEQEELLKFHYHTLRLYSAVCALGNNRVAHAMCSHVDESQL LYAIENKYMPGLLRAGYYDLLIDIHLNTYATARLMMNNEFIVPMTDETKSITLFPDENKK HGLPGIGLSTSLRPRMQFSSPSFVSISSECFQFSPEFPLEILKAKTIEMLTEAVQEGSLH VRDPVGGSTEFLFVPLIKLFYTLLIMGIFHNGDLKHILQLIEPRVFKEAMSQEDEVDFSE KELSSDELKSEEGEEETRGEQVPKEGLLQMKLPEPVKLQMCHLLQYLCDCQVRHRIEAIV AFSDDFVAKLQENQRFRYNEVMQALNMSAALTARKTKEFRSPPQEQINMLLNFKDDKNDC PCPEEIRDQLLDFHEDLMTHCGIELDEDGTLDGNSDLTIRGRLLYLMEKVTYLKKKQAEK PVDDDAKTSSTLQQLISDTMVRWAQESVIEDPELVRAMFVLLHRQYDGIGGLVRALPKTY TINSVSVEDTINLLASLGQIRSLLSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALG MHETVMEVMVNVLGGGESKEITFPKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSS VGLASPSMRGSTPLDVAAASVMDNNELALALREPDLEKVVRYLAGCGLQSCPLLISKGYP DIGWNPVEGERYLDFLRFAVFCNGESVEENANVVVRLLIRRPECFGPALRGEGGNGLLAA MEEAIQISEDPTRDGPSPSNGSSKTLEMEEQEDDTIHMGNAIMTFYAALIDLLGRCAPEM HLIHAGKGEAIRIRSILRSLIPLEDLVGVISIPFHMPTIAKDGTVVEPDMSAGFCPDHKA AMVLFLDRVYGIEDQDFLLHLLEVGFLPDLRAAASLDTAALSATDMALALNRYLCTAVLP LLTRCAPLFAGTEHHASLIDSLLHTVYRLSKGCSLTKAQRDSIEECLLSICGQLRPSMMQ HLLRRLVFDVPLLNEHAKMPLKLLTNHYERCWKYYCLPGGWGNFGAASEEELHLSRKLFW GIFDALSQKKYEQELFKLALPCLSAVAGALPPDYMESNYVNMMEKQSSMDSDGNFNPQPV DTSNITIPEKLEYFINKYAEHSHDKWSMEKFANGWTYGETYSESAKVQPLMKQYKLLSEK EKEIYRWPIKESLKTMLAWGWRIERTREGDSMALYNRTRRISQTSQISVDTAHGYTPRAI DMSNVTLSRDLHAMAEMMAENYHNIWAKKKKMELEAKVGGGNHPLLVPYDTLTAKEKAKD REKAQDILKFLQINGYVVSRGLKDLELDTPSIEKRFAYSFLQQLIRYVDEAHQYILEFDG GSRGKGEHFPYEQEIKFFAKVVLPLIDQYFKNHRLYFLSAASRPLSSGGHASNKEKEMVT SLFCKLGVLVRHRISLFGNDATSIVNCLHILGQTLDARTVMKTGLESVKMALRAFLDNAA EDLEKTMENLKQGQFTHSRNQPKGVTQIINYTTVALLPVLSSLFEHIGQHQFGEDLILED VQVSCYRILASLYALGTSKSIYVERQRSALGECLAAFSGAFPVAFLETHLNKHNIYSIYN TKNARDRAVLNLPTSVEEVCPNIPSLVKLMEEIVELAESGIRYTQMPHIMEVILPMLCSY MSHWWEHGPENNPDKAEMCCTALTSEHMNTLLGNILKIIYNNLGIDEGAWMKRLAVFSQP IISKAKPQLLKTHFLPLMDKLKKKAAVVVSDEEHLRAEGRGDMSEAELLILDEFTTLARD LYAFYPLLIRFVDYNRAKWLKEPNPEAEELFRMVAEVFIYWSKSHNFKREEQNFVVQNEI NNMSFLISDTKSKMSKAAVSDQERKKMKRKGDRYSMQTSLIVAALKRLLPIGLNICAPGD QELIALAKNRFSMKDTEDEVRDIIRSNLHLQGKLEDPAIRWQMALYKDLPNRTEDSSDPE KTVERVLDIANVLFHLEQVEHPQRSKKAVWHKLLSKQRKRAVVACFRMAPLYNLPRHRAV NLFLQGYDKSWIETEEHYFEDKLIEDLAKPGEEPPEEDESLKRVDPLHQLILLFSRTALT EKCKLEEDFLYMAYADIMAKSCHDEEDDDGEEEVKSFEVTGSQRSKEKEMEKQKLLYQQA RLHDRGAAEMVLQTISASKGEMGPMVAATLKLGIAILNGGNSTVQQKMLDYLKDKKDVGF FQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSVITHERGEKVMQDDEFTCDLFRFL QLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESISDFYWYYSGKDVIDEQGQ RNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVGFLHVFAHMQMKLSQDSS QIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVESSNNVEMILKFFDMFLKL KDLTSSDAFKEYDPDGKGIISKRDFHKAMESHKHYTQSETEFLLSCAETDENETLDYEEF VKRFHEPAKDIGFNVAVLLTNLSEHMPHDTRLQTFLELSESVLNYFQPFLGRIEIMGSAK RIERVYFEISESSRTQWEKPQVKESKRQFIFDVVNEGGEKEKMELFVNFCEDTIFEMQLA AQISESDLNERSANKEENEKDKPEEQDPRMGFFSLMTMKSALVALKYNLMTLMKMLSMKS LKKQMKKVKKMTMKDMVMALFSSYWSILMGLLHFACSVVRGFFRIICSLLLGGSLVEGAK KIKVAELLANMPDPTQDEVRGEGEEGERKPTEAALPAEDLTDLRTLSDESDLLSDIFGLD LKREGGQYKLIPHNPNAGLSDLLSTPSLAPMPEVQEKIQEQVKEDEKEEKEETKSEPEKA EGEDGEKEEKAKEDKGKQKLRQLHTHRYGEPEVQESAFWKKIIAYQQKLLNYFARNFYNM RMLALFVAFAINFILLFYKVSTSAVTEEKEVPVVSDAESTKLNSLESDNQRVIAVHYVLE ESSGYMEPTLRILAILHTVISFFCIIGYYCLKVPLVIFKREKEVARKLEFDGLYITEQPS EDDIKGQWDRLVINTQSFPNNYWDKFVKRKVMDKYGEFYGRDRISELLGMDKAALDFSDA REKKKPKKDSSLSAVLNSIDVKYQMWKLGVVFTDNSFLYLAWYMTMSVLGHYNNFFFAAH LLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFRKFYNKSEDGDMP DMKCDDMLTCYMFHMYVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFFFFVIVILLAII QGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQEHNLANYLFFL MYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN NT seq 14898 nt NT seq  +upstreamnt  +downstreamnt atggccgaggggggcgagggcgaggacgagatccagttcctgcgaactgatgatgaagtg gttctgcagtgcactgcaactgttcacaaggagcaacagaaactgtgtcttgctgctgaa ggatttggcaacaggctttgctttttggaatccacatcaaattctaagaatgttccacct gatttgtccatctgcacctttgtgctggagcagtccctgtcagtacgggccctccaggaa atgctggctaacacagaagaaaaggcagaagggctagttgatgtggaaaaatggtctgca caaggtggcgggcatcgaacgctactctatgggcatgcaatcttgctgcgccattcctac agcggcatgtatttatgctgcctctctacatctcgatcttcaatggataagctggcattt gatgtaggattgcaagaggacacaacaggtgaggcatgctggtggaccatccatcctgct tccaagcaacgatcagaaggagaaaaagtgcgtgttggagatgatcttattttagtcagt gtctcttcagaaagatatttgcatctctcttatggcaatggtagcttacatgttgatgca gccttccagcagacactctggagtgtagcaccaatcagttcaggaagtgaagttgcccaa ggatatctgatcggaggggatgttctgaggttattgcatggtcacatggatgaatgtttg acagtcccttcgggtgaacacggagaagaacaaagaagaactgttcattatgaaggcggt gctgtgtcaattcatgctcgttccctttggcgactagagactctaagagttgcgtggagt ggcagccacatcagatggggacagccattcagactaagacatataacaacaggaaaatat ttaagtctcctggatgacaagagtcttcttcttacagacaaagagaaagcagatgtaaaa tctacagcattctgttttcggtcctccaaggaaaagttggacacagggacaagaaaagaa gtggatggaatgggagcacctgaaataaaatacggggattcaatatgcttcatacaacat gtagatacaggcttatggctcacgtaccagtctgctgatgcaaagtctgtacgaatgggt tctgtgcagcggaaggcaataatgcaccatgaaggtcatatggatgatggtttaacattg tccagatctcagaatgaagaatcccgaacagcacgtgtcatccgcagtacggtcttcctt ttcaacaggtttataaggggccttgatgctctcagcaagaaagcgaagtcttccaccgtc gatttgcctattgagtcagtcagtctgagccttcaggacttgattgggtactttcacccc cctgatgaacatttggagcatgaagataaacaaaacaggctccgagcactgaagaatcgc cagaacctcttccaggaagagggtatgatcaaccttgttcttgaatgtattgatcgcttg aatgtatacagcagtgcagctcattttgcagacgtagctgggaaggaagctggagaagca tggaaatctattctgaattctttgtatgaattgctagcggctctgattcgagggaatcgt aaaaactgtgctcagttttctggatctcttgattggttgatcagcagattagaaagactg gaagcctcttctggaattctggaggttttacactgtgtgttggtggaaagcccagaagct ctaaacattattaaggaaggacatattaagtcaatcatctgtcttttggacaaacatgga agaaaccataaggttttggatgttttgtgttctctctgtgtttgtcatggagtagctgtt cggtctaatcaacatctaatctgtgataatctcctaccaggaagagatctgctcttacag acacgccttgtcaaccacgtgagcagcatgcgacccaacatcttcttggggattagtgaa ggctctgcccaatacagaaaatggtactatgaacttatggtggaccatctagagcccttt gtgactgcagaatcaactcatctacgagtaggctgggcttcaacagagggctactcacca tacccagggggaggagcagaatggggaggaaatggtgttggtgatgacttgtattcctat ggtttcgatggtctgcatctgtggtcaggttgtgttgcacgaacagtaaattctcccaac caacatctgttaagaactgatgatgttattagctgctgtttggacctgagtgcccccagc atctctttccggataaatggtcagccagttcaaggaatgtttgagaatttcaacatagat ggcctcttcttcccagttgtcagcttctctgcaggaataaaagtacgtttcttacttgga ggtcgccatggagagttcaagttccttcctccacctggatatgccccttgctttgaagct gtactaccgaaagagaagctcaaagtggagcatagccgagagtacaagcaggaccgtagc tatacaagagacctactgggtcccactatctctctgtcacaagcagctttcactccagtt cctgtagatactagccagattgttttgcctccccacctggaaaggattagagaaaaatta gcagagaacatccatgaactttgggttatgaataagattgaacttggctggcagtatgga ccagttagagatgacaacaaaagacaacacccatgtttagtggagttctcaaaattgccg gagcaggagagaaattataacttgcagatgtcacttgaaacactgaaaaccctgctggca ttaggctgccatgttggaattgctgatgaacatgctgaagaaaaagtgaaaaaaatgaaa cttccaaagaactaccagttgttgagtggatataagcctgctcccatggatctgagtttt atcaaactgaccccttctcaagaagctatggtggataaactagcagagaatgctcacaat gtgtgggcaagggaccgtataaggcaaggctggacatacggtatccagcaggatgtgaaa aatcgacgaaatcctcgccttgtgccttatgctcttctggatgatcgaacgaagaagtca aacaaagacagtcttcgggaagcagtccgcacccttctaggctatggttacaacctggaa gctcctgatcaagaccatgcaatgagactggacgtgtgcagtgggataatggaaaaattc aggatcttccgcacagaaaagacttatgcagtgaaggctgggaagtggtactttgaattt gaggcagttactgcaggagacatgagagttggctggaccaggccgggttgtctgccagat caggaacttggctcagatgaagaagcttttgtttttgatggctttaaggcacagcggtgg catcaaggtaatgagcattttggccgctcttggttagcaggagatgttgttggatgtatg gttgacatgaatgagcacactatgatgttcaccttaaatggtgaaatcttgcttgatgac tcaggttcagaacttgcattcaaggactttgaggttggtgacggttttctacctgtgtgc agcctgggcccatctcaagtgggaagaatgaactttggaaaagatgtcagcacgctaaaa tatttcactatctgtggcttacaggaagggtatgaaccctttgctgttaatacaaacaga gacatcaccatttggctgagtaaaaggctccctcagtttctaccagtgccacaaaatcat gaacatattgaggtgatgagaattgatggcaccatagacagctgcccctgcctgaaggtc acacagaagtcctttggttcacagaacagtaaaacagacgtcatgttttttcgattaagc atgcccatcgaatgtgctgaggtattctccagatcagctgcaggagggttaccaggctct ggtctttttggcccgaagaatgacttggaggattatgatgctgattctgattttgaggtt ctaatgaaaactgctcatggtcatctagttcctgaccggacagaacgagaaaaagatgcc acaaaaccagagttaaacaaccataaagattatgttcaagaaaagccttcacgtcttaaa caaagatttatgcttaggaggacaaagccagattatagcactagtcactctgcacggctt actgaggatgtgctagcagatgatagggatgactatgattatttgatgcaaacttccacg tactattattcagtgagaatatttcctggtcaagaacctgccaatgtctgggtgggctgg attacatctgactttcaccagtatgacacaagctttgatttggacagagtgcgtactgtc acagttacactgggagatgaaaaagggaaggttcatgagagtataaaacgcagcaactgc tatatggtgtgcgcaggagagagcatgagccctggacaaggacgtaataataatggtctg gagattggttgcttggttgatgctgccagtggcttgctgactttcacagctaatggcaag gaactgggcacatactatcaggttgaaccgagtacaaaattatttcctgctgtatttgct caagctacaagccccaatgttttccagtttgaattgggaagaataaagaatgtaatgccg ttatctgctggcttattcaaaagtgaacacaaaaacccagtctctcaatgtcctccacga ctccatgtccaatttctgactcatgtgctttggagcagagtgccaaaccacttcttgaag gttgatgtctctcggatcagtgaacgtcaagggtggatgatacagtgcctgaatcctttg cagttcatggcccttcatattcctgaagaaaacagaacaattgatattttagagctgaca gaacaagaagaattgctgaaatttcactaccataccctccgactatattcagcagtttgt gctttaggcaacaaccgagtggcccatgctatgtgtagccatgtggatgaatctcagctc ctgtatgctattgagaataaatatatgccaggattattacgtgcaggatattatgactta ctcattgacatccatctcaatacctatgcaactgccaggttaatgatgaataatgaattt atagttccaatgacagatgagaccaagagcattactttgtttcctgatgaaaacaaaaaa catggcctccctggtattggacttagcacttcattaaggccaagaatgcagttctcctct ccgagttttgtaagcattagcagtgaatgctttcagttcagtcctgaattccctctggaa atcttaaaggccaaaaccatagagatgctgactgaagctgttcaggagggcagcctccat gtcagagatccagttggaggttctacagaatttctgtttgtccctctcatcaagctcttc tataccctcctaataatgggaatcttccacaatggggatctgaaacacatcttgcagttg attgagcccagggttttcaaagaggcaatgagccaggaggatgaagttgatttctcagag aaggagctgagttcagatgagctcaagtcagaagaaggagaggaagaaaccagaggggag caagtgccaaaggaaggactccttcagatgaaacttccagaacctgttaaattacagatg tgccatctactccagtacctgtgtgattgccaagtacgacaccgaatagaagccattgta gcattttcagatgattttgtagccaagcttcaagagaatcaacgcttccggtacaatgaa gtgatgcaggccttgaacatgtctgctgccctgactgctagaaaaacaaaagaatttcga tccccacctcaggagcagattaacatgctgctgaactttaaagatgataaaaatgattgt ccttgccctgaagaaattcgggatcagctcttggatttccatgaagacctaatgacacac tgtggaattgaactagatgaagatggaaccttggatggaaacagtgatttaaccattagg ggtcgcctcctataccttatggaaaaagttacatatctgaagaagaagcaagctgagaag ccagttgatgatgatgctaagacatcctctactcttcagcagttgatttcagacacaatg gtacgctgggcccaggaatcagtgatagaagacccggagttagtaagggccatgtttgta ttgctacaccgacaatatgatggtattggtggcctggttcgagccctaccaaagacgtac accataaatagtgtgtctgtggaagacacaatcaatcttctggcatccctcggccaaatc cgttccttgcttagtgtcagaatggggaaggaggaagagaaacttatgattcgtggatta ggagacatcatgaataataaagtattttaccaacatccaaatctcatgagagctttaggc atgcatgaaactgtcatggaagtgatggtaaatgtgcttggtggaggagaatccaaggaa atcactttcccaaagatggtggcaaactgctgtcgttttctatgttatttttgccgcatc agcagacagaatcaaaaagctatgtttgatcatcttagctatttattggaaaacagcagt gttggccttgcctctccttctatgcgaggatcaactcctttagatgttgcagcagcctct gtgatggataacaatgaacttgcactagctttaagagaacctgatctggagaaggtggtt cgctacttggctggatgtggattgcagagttgtcctttgttgatttctaaaggctaccca gacatcggatggaatccagttgaaggagagcgatatttggattttcttcgttttgctgtt ttctgcaatggagagagtgtggaggagaatgctaatgttgtagtcagactgcttatccgt cgacctgaatgttttggaccagctctaagaggagaaggaggcaatgggttacttgctgcc atggaggaagcaatacaaatatcagaagatccaacaagagatggaccttccccgagtaat ggatctagtaaaacccttgaaatggaagaacaagaagatgacactattcacatgggaaat gcaatcatgaccttttatgctgctttgattgatctgttaggacgttgtgcccctgaaatg cacctaatccatgctggtaaaggggaagccattagaatcagatcaattctacggtctttg attccactggaagatttggtgggagtaattagtattcctttccacatgccaaccatagct aaagatggtactgtggtggaacctgacatgtctgcggggttttgcccagatcacaaggca gccatggttttgttccttgacagggtctatggaattgaggaccaggattttcttctacac cttcttgaagttggctttctgccagatcttcgtgctgctgcttctttagatacagctgct ttaagtgctacggatatggctttggctctgaatcggtacctttgcacagcagtcttgcct ctgttgaccagatgtgctcctctttttgctggcacagagcaccatgcttccctcatcgat tcgttattacatactgtgtacagactctcaaagggatgctctcttaccaaagctcagcga gattctattgaagagtgtttgctgtctatctgtgggcagttgcggccttccatgatgcag catttgctgagaagattagtatttgatgttcctctattaaatgaacatgcgaagatgcct ctcaagttgctgacaaatcattatgaaagatgctggaagtattattgtttgccaggtgga tggggtaactttggtgctgcctcagaagaagaacttcatttatccagaaagttgttctgg ggtatttttgatgctttgtctcaaaagaagtatgaacaagaactgttcaaattggctttg ccttgtttgagcgcagttgcaggggccttacctccagactatatggaatcaaattatgtc aatatgatggaaaaacagtcttcaatggattcagatgggaactttaatcctcaacctgtt gatacatcaaacattacaatacctgaaaagctagaatatttcattaacaaatatgcagaa cactctcatgacaaatggtcaatggaaaagtttgccaatggatggacatatggtgaaaca tattctgaatctgcaaaagtgcaaccattaatgaaacaatataagttactgtctgaaaag gagaaagaaatttatcgatggccaatcaaagaatcgctgaaaactatgctggcatgggga tggcgaattgaaagaacacgggagggagattccatggcactgtataatcggacacgtcgc atatctcaaaccagtcaaatctctgtagatacagcccatggttacactcctcgagcgatt gacatgagcaatgtcaccctctccagagacttacatgctatggccgagatgatggctgaa aactaccataacatatgggcaaagaaaaagaaaatggagcttgaagcaaaagtaggagga ggcaaccatcctcttcttgttccttatgatacactcacagccaaagaaaaagccaaggac agagaaaaagcacaggacattctgaaatttctacagattaatggatatgttgtctccaga ggacttaaggacctggaattggacacaccttccattgagaaacgctttgcctacagtttc cttcagcaacttataagatatgtcgatgaagcccatcagtacattctggagtttgatggt ggcagcagaggcaaaggagagcacttcccatatgagcaagaaatcaagttttttgccaaa gttgtgctccctttgattgatcagtattttaaaaatcatcgcctgtatttcttatctgca gcaagtaggcctctgagcagtggaggccatgcctctaataaagagaaagaaatggtgaca agcctgttctgcaaacttggagttcttgtcaggcataggatttcactgtttggaaatgat gcaacatcaatagtcaactgtcttcacatactgggccagaccttggatgcaaggactgtg atgaaaactggtctggaatctgttaagatggcattgagagcatttttggacaatgctgct gaggatctggagaaaacaatggaaaatcttaagcaaggccagtttacacacagcagaaac cagccaaagggagttacacaaatcattaattataccacagttgctctcctgccagtgcta tcttcattatttgagcatattggacagcaccagtttggggaagatttgatattggaagat gttcaggtctcctgctacagaatattggccagtttatatgctctgggaaccagcaagagt atctatgtagagcggcaacgatcagcactaggagaatgcttggctgctttctcaggggcc tttccagtggcttttttggaaactcatttgaacaaacataacatctactcaatttacaat accaagaatgcaagagacagagcagttctcaatttgcctactagtgtagaagaggtttgc ccaaatattccctccttggtgaagctaatggaagaaattgtggaactggcagagtctggt attcgttacacacaaatgccacatatcatggaagtaatactgcctatgctgtgtagttac atgtcacactggtgggagcatgggccagaaaacaaccctgacaaggctgaaatgtgttgc acagccttgacatcagagcacatgaacactctgttgggtaacatattgaaaatcatctat aacaaccttggtattgatgaaggagcctggatgaagagattagcagtgttttcccagccc atcataagcaaagcgaagccacagctcttaaagacacacttcctgccactgatggataag ctaaagaaaaaagcagcagtggttgtatcggatgaagaacatctaagagcagaaggcaga ggtgacatgtcggaggctgaactgctcatcctagatgagttcaccactttggcacgggac ctctatgccttctaccctttgttgattagatttgtggactataacagggcaaaatggctg aaagagcccaaccctgaagcagaagaattgttccgcatggtggctgaggtcttcatttac tggtcaaagtctcataatttcaaaagggaagagcagaactttgtggtacaaaatgaaatc aacaacatgtctttccttattagtgacaccaaatccaagatgtccaaggcagcagtttct gaccaggagaggaagaagatgaagcgaaaaggtgaccggtactctatgcagacctctctc attgtggcagcattgaagagattacttcctattggcctaaacatttgtgctcctggagac caagagctaattgcactggccaaaaatcgattcagtatgaaagatactgaagatgaagta cgagatatcatccgcagtaatcttcacctccagggcaagcttgaggatcctgccattagg tggcagatggcactttacaaagatttaccaaacaggactgaagattcctcagatccagag aagactgtggaaagggtccttgatatagctaatgtactgtttcacctggaacaggttgag catcctcagcggtccaaaaaagcagtgtggcataagctgctgtctaaacagaggaaaaga gcagtagttgcctgctttagaatggcaccattgtataatctgccaaggcaccgagccgtc aatctctttcttcaaggctatgataaatcttggattgagacagaagaacactattttgaa gacaaactgatagaagacttagcaaaacctggggaggaaccaccggaagaagatgaaagc cttaaaagagttgatcctttacatcaacttattctgctattcagtcgaacagccttgact gaaaaatgtaaattggaagaagatttcctgtatatggcttatgctgacattatggcaaag agctgccatgatgaagaagatgatgatggtgaagaagaagtgaagagttttgaagtgaca ggatcacagcgcagcaaggaaaaagaaatggaaaagcaaaaacttctgtatcaacaagcc agactgcatgaccggggtgctgctgagatggttctgcagacaatcagtgctagtaaaggt gagatggggccaatggttgcagctaccctaaagctagggattgccatcttaaatggagga aattctaccgttcaacagaaaatgcttgactacctcaaggataaaaaggatgtcgggttc tttcagagccttgctggtcttatgcagtcctgtagtgttcttgacctaaatgcgtttgaa cgtcagaacaaagcagaaggccttggcatggtgactgaagagggatcagtcatcactcat gagcgtggagaaaaggtgatgcaggatgatgagttcacctgtgatctcttccgcttcctt caattgctttgtgaaggacataattcagattttcagaattacctgagaactcagactggt aacaacacaactgttaatattatcatttccactgtggattacttattaagagttcaggaa tccattagtgatttctattggtattattctgggaaggatgttattgatgagcaaggacaa cgaaatttttccaaagccatccaggttgcaaaacaagttttcaatactcttacagagtat atccaggggccatgtactgggaatcagcaaagcctggcacacagcaggctatgggatgct gtggttggttttcttcatgtgtttgcccacatgcagatgaagctttctcaggattccagt caaattgaattactgaaggaattaatggatcttcagaaggatatggttgtcatgttgctg tctatgctggaaggtaatgttgtgaatggaactattggcaagcagatggtcgatatgctt gtggaatcgtccaacaacgtggagatgattctgaagttttttgatatgttcttaaaattg aaggatttgacttcctctgatgcattcaaagaatatgaccctgacggtaaagggataatt tcaaagagggattttcacaaggcaatggaaagccataagcattacacccagtctgaaact gagtttctactatcgtgtgctgaaacagatgagaatgagactctggactatgaggagttt gtgaaacgattccatgaacctgccaaagacattggtttcaatgtcgctgttctcctgacc aacctgtcagaacacatgccacatgacacccgcttgcaaacttttcttgaactgtcagag agtgtgctgaattactttcagcctttccttgggcgcatagaaatcatgggcagtgcaaag cgcattgaacgagtttattttgaaataagcgagtcaagtcggactcagtgggagaaacct caggtaaaagagtcaaagagacaatttatatttgatgttgtaaatgaaggcggggagaaa gaaaagatggagctttttgttaatttctgtgaggataccatctttgaaatgcagctggct gcccagatctctgagtcagatctgaatgaaaggtcagcaaataaagaggagaatgagaaa gataagcctgaagagcaggatcctagaatgggtttcttctccctcatgaccatgaagtca gctttagtagcgctcaagtataatttaatgactcttatgaaaatgctcagcatgaaaagc ctaaagaaacagatgaaaaaggtgaagaaaatgaccatgaaggacatggtcatggccttg ttttcttcctattggagcattttgatgggcttactacattttgcttgtagtgtcgtccgg ggcttctttcgcatcatatgcagtttgctgcttggaggaagcctagtagaaggagcaaag aaaatcaaggtggctgaactgttagctaatatgccagatcccactcaggatgaggtgcgt ggggaaggagaagagggggaaaggaagccaacagaagctgcattgcctgcagaagacttg acagatctgagaactttgtcagatgagagtgatctactctcagatatatttggtttggat ttgaaacgagaaggtgggcagtataaattgatccctcacaatccaaatgctggtttgagt gatttactgagcactccctccttagctccaatgcctgaggtgcaggaaaaaatccaggag caggtgaaagaagatgaaaaggaagagaaggaggaaacaaaatctgaacctgaaaaagca gaaggagaagatggagaaaaagaagagaaagccaaggaagacaaagggaaacagaaattg agacaactccatactcacagatatggagaaccagaagttcaggaatcagctttctggaag aagatcattgcataccaacagaagcttcttaattattttgcgcgaaacttttataacatg aggatgttggcgttgtttgttgcttttgccatcaacttcatcctgcttttctataaggtc tccacctctgctgtgacagaagaaaaggaagttcctgtggtatctgatgctgaaagtacc aaattaaacagcctggaaagcgacaaccagagggtcatagcagtgcattatgtcctggaa gaaagcagtggctacatggagcccacactgcggattttggccatcctgcacacagtcatc tcattcttctgcatcatagggtattactgtttgaaagttccactggttatttttaagaga gaaaaggaagtggcaaggaaattggaatttgatgggttgtatataactgaacagccatca gaagacgatattaagggacagtgggacagactcgtaatcaacacacagtcttttccaaat aattactgggacaaatttgtgaaaagaaaggtcatggataaatatggtgagttctatggc cgtgacaggatcagtgaattactaggaatggacaaagctgctctcgattttagtgatgct cgagaaaagaagaaaccaaagaaggatagctccttatctgctgtgctaaattccattgat gttaagtatcagatgtggaaattaggagttgttttcactgataattctttcctttaccta gcgtggtacatgaccatgtcagtccttggccattacaacaattttttctttgctgctcat ctccttgacattgcaatgggattcaagactttacgaactatcctgtcatcagtgactcac aatggcaaacagcttgtcctaacagtgggattactcgcagtagtagtatacttgtataca gtagtggcattcaattttttccgcaagttctacaacaagagtgaagatggtgatatgcca gacatgaaatgtgatgatatgctaacatgctacatgtttcacatgtacgttggagtacgt gcaggtggaggcattggtgacgagatcgaggatccagcaggagatgaatatgaaatctat cggattatctttgacatcactttcttcttctttgtgattgtcatcctgcttgcaattatt caaggtttaattattgatgcttttggtgagttaagagatcagcaagagcaagttaaggaa gacatggagacgaagtgctttatctgtggaataggaaatgactactttgatacagtgccc catggctttgaaacacacactctacaggagcacaacttggccaattatttgttttttctg atgtatcttattaacaaagatgaaacagagcatacaggacaggaatcctatgtatggaaa atgtatcaagaacggtgctgggagtttttccctgctggtgattgcttccgaaaacagtat gaagaccagctcaattaa

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