Actinomyces graevenitzii: M3I41_05430
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Entry
M3I41_05430 CDS
T08387
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
agh
Actinomyces graevenitzii
Pathway
agh00300
Lysine biosynthesis
agh00550
Peptidoglycan biosynthesis
agh01100
Metabolic pathways
agh01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
agh00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
M3I41_05430
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
M3I41_05430
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
M3I41_05430
Enzymes [BR:
agh01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
M3I41_05430
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
LUD_dom
Motif
Other DBs
NCBI-ProteinID:
UQF79055
UniProt:
A0A9E7AEB9
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Position
complement(1269780..1271189)
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AA seq
469 aa
AA seq
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MSGMCRDAAWLASACEGQLVGLEGTELVSAPVVIDSRKVSDHGCFVAIVGENADGHDYAP
AAYNSTEGLVVISSKDLDVPHIRVQDTVDALGKIAYSYLREIRQYREANGLPFDVAGVTG
SVGKTTTKDLTRQIFASQGPTVAPQASFNNEIGLPLTILEADNDTRYLLLEMGASGPGHI
AYLTDIAPLDVAAVLMVGHAHMGGFGSVEAVARAKSEIIQGLRSSGVAILNADDPRTMAM
AELAPGPVFSFSPSGEPANVRADDVVIGPDGRASFTARTAGASAPVQLQLVGAHHVANAL
AALTIALVVGIDLQAAAQVLSQAQALSPHRMDVHSLSGQLLLIDDSYNANIDSVTAALVA
LKQLAGKRRKVFVAGQMLELGDTSEQVHTRTAELAHEAGVSDIVAIGEAARPLARRAREL
GIATTYVDDADQALAMIDQIVADFDAVLVKGSHSSGAWRIADYLKEVRA
NT seq
1410 nt
NT seq
+upstream
nt +downstream
nt
atgagtggcatgtgtcgcgacgccgcttggctagctagcgcctgtgaaggccagctggtg
ggccttgagggcactgagctagttagcgccccggtagttattgactcacgcaaggttagt
gaccacggctgttttgtggccattgtgggtgaaaacgcagacgggcatgactacgcaccc
gccgcctataactccaccgaggggcttgtagttatcagctccaaggatctggacgtgccc
cacattcgcgtccaagacactgttgatgcgctaggcaaaattgcctacagctacctgcgt
gagatccgccagtaccgtgaagctaacggtttgccctttgatgtggccggcgtaactggc
tcggttggtaaaactaccaccaaggatctaacccgccagatttttgcctcccagggcccc
acggtagccccgcaagcctccttcaataacgagatcggcttgccgctaaccattttggaa
gccgataacgacacccgctacctgctgctagaaatgggtgcctcggggcctgggcacatc
gcctacctgaccgatattgcccccctggacgtggccgcagtgcttatggtgggtcacgcc
cacatgggtggttttggttcagttgaggctgtggctcgcgctaagagcgagattatccag
ggcttgcgtagcagcggggtggcgattttgaacgctgacgacccgcgcaccatggccatg
gctgagctagctcccggcccggtatttagcttctcaccttcaggcgagcccgctaacgta
cgtgccgacgacgtcgtcattggccccgacggacgcgccagcttcaccgcccgcaccgct
ggcgccagtgccccagtccagctacagctagtgggcgcgcaccatgtggctaacgccctg
gcggcgctaaccattgccctagtggtgggcattgatctgcaagccgccgcccaggtactc
agccaagcacaggcccttagcccgcaccgtatggatgtgcatagcctaagcggacagctg
ctgctaattgacgactcttacaacgccaatattgactccgtaactgccgccctagtggca
cttaaacagctagctgggaagcgccgcaaggtgtttgtagccgggcagatgctggagcta
ggcgacacctctgagcaagtgcatacgcgcactgccgagctggcccatgaggccggcgtg
agcgacattgtggccattggcgaagctgcccggcctcttgcccgccgcgcccgcgagtta
ggcattgccaccacttacgttgacgatgctgatcaggctttggccatgattgatcagatc
gtggcagacttcgatgcagtgttggttaaagggtcccactcctcaggggcctggcgaatt
gccgactatctcaaggaggttcgcgcctaa
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