Actinobacillus genomosp. 2: NYR60_08610
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Entry
NYR60_08610 CDS
T09470
Symbol
gshAB
Name
(GenBank) bifunctional glutamate--cysteine ligase GshA/glutathione synthetase GshB
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
agk
Actinobacillus genomosp. 2
Pathway
agk00270
Cysteine and methionine metabolism
agk00480
Glutathione metabolism
agk01100
Metabolic pathways
agk01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
agk00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
NYR60_08610 (gshAB)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
NYR60_08610 (gshAB)
Enzymes [BR:
agk01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
NYR60_08610 (gshAB)
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATP-grasp_3
ATPgrasp_ST
GARS_A
Dala_Dala_lig_C
Motif
Other DBs
NCBI-ProteinID:
WGE31891
LinkDB
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Position
complement(1717122..1719395)
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AA seq
757 aa
AA seq
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MKLQQLIKTHQLGLLFQQGKFGIEKESQRIDHKGNIVTTTHPAVFGNRSYHPYIQTDFAE
SQLELITPPNDKLEDTYRWLSAIHEVTLRSLPNDEYIFPFSMPAGLPPESEIKEAQLDNE
WDVKYREHLSAIYGKYKQMVSGIHYNFQISDEFVESAFALQTEYNDKIAFRNALYMKLAN
NFLRYQWILVYLLAATPTVESQYFGKNSPLAEGQLVRSLRSGPYGYVNAPHIVINHDSLQ
QYVESLEHFVATGDLLAEKEFYSNVRLRGAKKARELLEKGVKYAEFRLFDLNPFSPYGIE
LADAKFIHLFLLAMLWIDETSGQKEVEIGTQKLYQVALEDPRSHTAFQAEGEAILNLMLA
MLEDLSAPQREKDLLQQKLAQFADPSQTVNGRLLSAIEQAGNYKALGAKLAQQYKAQAFD
RFYAISAFDNMELSTQALLFDAIQQGLQIELLDENDQFLALKFGDHLEYVKNGNMTSHDQ
YISPLIMENKVVTKKVLAKAGFNVPKSVEFTSVEQAVAHYPLFEGKAVVIKPKSTNYGLG
ITIFQQGVTDKADFAKAIEIAFREDKEVMVEDYLVGTEYRFFVLGDETLAVLLRVPANVK
GDGTHTVRELVEAKNSDPLRGDGSRSPLKKIALSDIELLQLKEQGLTPDSIPAEGQIVQL
RANSNISTGGDSIDMTDQMHDSYKQLAVGIAKAMGAKVCGVDLIIPDLTKAAEPSLRSWG
VIEANFNPMMMMHIFPYQGKSRRLTKAVLKMLFPELP
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgaaattacaacaacttattaaaacacatcaacttggcttactatttcaacaaggcaaa
ttcggtattgagaaagaaagccaacgtattgatcataaaggaaatattgttaccactaca
catccagccgtttttggtaatcgcagttatcatccatatattcaaactgatttcgcagaa
agccaactggaattaatcacgccgccaaacgataaattggaagacacatatcgttggcta
tcggctattcacgaggtaacgttacgctcgttgcctaacgatgaatatattttcccattc
agtatgcctgccggtttaccaccggaatccgagatcaaagaagcacaattagataacgaa
tgggacgtgaaatatcgtgaacacctttctgcgatttatggcaaatacaaacagatggta
agcggtattcactacaatttccaaatttctgacgagtttgtcgagagtgcatttgcatta
caaacagaatacaacgataaaattgcgttccgtaatgcattatatatgaaattagccaat
aactttttacgttatcaatggattctggtctatttgcttgcggcaacgccaaccgtagaa
tcgcaatatttcggtaaaaattcacctcttgcagaggggcaattagtacgtagtttacgt
tctggcccttatggttatgtaaatgcaccacatattgtgatcaatcacgacagcttgcaa
caatatgtcgaatccttagaacattttgttgcaactggtgatttattggcagaaaaagaa
ttctattcaaacgttcgtttacgtggtgcgaaaaaagcacgcgaattgcttgagaaaggg
gttaaatatgcggaattccgtttatttgatctcaacccgttctcgccttacggtatcgag
ctcgccgatgccaaatttattcatctattcttactcgctatgctatggatagatgaaaca
agcggtcaaaaagaagttgaaattggcacacaaaaactataccaagttgcattagaagat
cctcgctcacatactgcgttccaagcagagggtgaagctattcttaacctaatgctggca
atgttagaagatctttcagcgccacaacgcgagaaagatttattacaacaaaaactggca
caatttgccgatccgagccaaacagtaaacggtcgtttattatctgcaattgaacaagcc
ggcaattataaagcactcggtgcaaaacttgcacaacaatataaagcacaagcattcgat
cgtttttatgcgatttccgctttcgataatatggagctttctacacaggctttattattt
gatgcgatccaacaaggattgcagatcgaattgctggatgaaaacgatcagttcctcgca
ctcaaattcggtgatcaccttgaatatgtgaaaaacggcaatatgaccagtcacgatcag
tatatttctccattaattatggaaaataaagttgtgaccaaaaaagtgttagcaaaagcc
ggttttaatgtgccgaaaagcgttgaatttacctcggtagaacaggcagtggcgcactat
ccgttatttgaaggtaaagcggtggtgattaagccgaaatcgaccaattacggtttgggc
attacgattttccaacaaggcgtgacggataaagccgattttgccaaagcgattgaaatt
gccttccgtgaagataaagaagtaatggtggaagactatttagtcggcactgaatatcgt
ttctttgtgttaggagatgaaacactagcggtattgttacgtgtaccggcaaatgtaaaa
ggtgatggtacgcatacagtgcgtgaattagtggaagcgaaaaacagcgatccgctacga
ggagacggctctcgttcgccattgaaaaaaatcgccctcagtgacattgaattgcttcaa
ctcaaagagcaaggtttaacgcctgattcaattccagctgaaggacaaatcgtacaatta
cgtgccaactctaatattagtaccggtggtgattcaatcgatatgaccgatcaaatgcac
gacagctataaacaattagctgtcggtattgctaaagcaatgggggcaaaagtctgcggt
gtggatttaatcattccagatttaactaaagctgctgaaccgtctctacgttcatggggg
gttattgaagcaaactttaatccgatgatgatgatgcatattttcccttaccaaggaaaa
tctcgtcgcttaaccaaagcggtgttaaaaatgctgttccctgaactgccttaa
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